Efficient presentation of house dust mite allergen Der p 2 by monocyte- derived dendritic cells and the role of β2 integrins

Scandinavian Journal of Immunology

Volumn 49, Issue 1, 1999, Pages 96-105

  Sung, S S J ^a   Taketomi, E A ^a,b   Smith, A M ^a   Platts Mills, T A E ^a   Fu, S M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HOUSE DUST ALLERGEN; INTEGRIN; INTERLEUKIN 5;

ALLERGY; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DIAGNOSTIC VALUE; HOUSE DUST; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PHAGOCYTOSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

ALLERGENS; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD18; ANTIGENS, DERMATOPHAGOIDES; CELL COUNT; CELL SEPARATION; CELLS, CULTURED; DENDRITIC CELLS; DIPHTHERIA TOXOID; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DUST; GLYCOPROTEINS; HUMANS; HYPERSENSITIVITY; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE ACTIVATION; MITES; MONOCYTES; PHAGOCYTOSIS; T-LYMPHOCYTE SUBSETS; TETANUS TOXOID; TH1 CELLS; TH2 CELLS;

EID: 0032894107     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. + T cell responses: the alternative response. Annu Rev Immunol 1997;15: 297-322.
2. 2 McWilliam AS, Nelson DJ, Holt PG. The biology of airway dendritic cells. Immunol Cell Biol 1995;73:405-13.
3. 3 Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigens by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J Exp Med 1994;179:1109-18.
4. 4 Romani N, Gruner S, Brang D et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994;180:83-93.
5. 5 Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-62.
6. 6 Thomas R, Davis LS, Lipsky PE. Isolation and characterization of human peripheral blood dendritic cells. J Immunol 1993;150: 821-34.
7. 7 Zhou L-J, Tedder TF. Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J Immunol 1995;154:3821-35.
8. 8 Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 1995;182:389-400.
9. 9 Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavecchia A, Alber G. Ligation of CD40 on dendritic cell triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 1996;184:747-52.
10. 1 peripheral blood monocytes. J Immunol 1996;157:3850-9.
11. 11 Okano M, Nagano T, Kino K et al. Population analysis of cellular responses to synthetic peptides of Der p II, a major allergen molecule of Dermatophagoides pteronyssinux, in allergic and nonallergic subjects. Allergy 1994;49:436-41.
12. 12 van Neerven RJJ, vant'Hof W, Ringrose JH et al. T cell epitopes of house dust mite major allergen der p II. J Immunol 1993;151: 2326-35.
13. 1 T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell types. J Exp Med 1995;181:1081-9.
14. 14 Koch F, Stanzl U, Jennewein P et al. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med 1996;184:741-7.
15. 15 Trinchieri G. Role of interleukin-12 in human Th1 response. Chem Immunol 1996;63:14-29.
16. 16 Okano M, Nagano T, Nakada M et al. Epitope analysis of HLA-DR-restricled helper T-cell responses to Der p II, a major allergen molecule of Dermatophagoides pteronyssinux. Allergy 1996;51: 29-35.
17. 17 Verhoef A, Higgins JA, Thorpe CJ et al. Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes. Int Immunol 1993;5:1589-97.
18. 18 Sporik R, Chapman D, Platts-Mills TAE. House dust mite exposure as a cause of asthma. Clin Exp Allergy 1992;22:897-906.
19. 19 Mueller GA, Smith AM, Williams AE Jr et al. Expression and secondary structure determination hy NMR methods of the major house dust mite allergen Der p 2. J Biol Chem 1997;272:26893-8.
20. 20 Sung SJ, Guo CY, Weed JM. Monoclonal antibodies against human dendritic cell-like peripheral blood monocytes activated by granulocyte/macrophage-colony-stimulating factor plus interleukin 4. Cell Immunol 1997;182:113-24.
21. 21 Sung SJ. Phagocytosis by mouse peritoneal macrophages plated on monoclonal antibody-coated immune complex-substrates: effects of complexes of different IgG subclasses on Fc receptor functions. J Immunol 1985;135:1981-6.
22. 22 O'Doherty U, Peng M, Gezelter S, Swiggard WJ, Betjes M, Bhardwaj N. Human blood contains two subsets of dendritic cells, one immunologically mature and the other mature. Immunology 1994;82:487-93.
23. 23 Flechner ER, Freudenthal PS, Kaplan G, Steinman RM. Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction. Cell Immunol 1988;111: 183-95.
24. 24 Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. J Exp Med 1974;139:380-97.
25. 25 Dustin ML, Springer TA. Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annu Rev Immunol 1991;9:27-66.
26. 26 Gieni RS, Umetsu DT, DeKruyff RH. Ly1-(CD5-) B cells produce interleukin (IL)-10. Cell Immunol 1997;175:164-70.
27. 27 Albert ML, Sauter B, Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 1998;392:86-9.
28. 28 Chapuis F, Rosenzwajg M, Yagello M, Ekman M, Biberfeld P, Gluckman JC. Differentiation of human dendritic cells from monocytes in vitro. Eur J Immunol 1997;27:431-41.
29. 29 Silverstein SC, Steinman RM, Cohn ZA. Endocytosis. Annu Rev Biochem 1977;46:669-722.
30. 30 Sung SJ, Nelson RS, Silverstein SC. Yeast mannans inhibit binding and phagocytosis of zymosan by mouse peritoneal macrophages. J Cell Biol 1983;96:160-6.
31. 31 O'Hehir RE, Hoyne GF, Thomas WR, Lamb JR. House dust mite allergy: from T-cell epitopes to immunotherapy. Eur J Clin Invest 1993;23:763-72.
32. 32 Engering AJ, Cella M, Fluitsma D et al. The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells. Eur J Immunol 1997;27:2417-25.
33. 33 Tan MC, Mommaas AM, Drijfhout JW et al. Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells. Eur J Immunol 1997;27:2426-35.