Double-blind comparison of citalopram and placebo in depressed outpatients with melancholia

Depression and Anxiety

Volumn 9, Issue 2, 1999, Pages 54-60

  Mendels, Joseph ^a,b   Kiev, Ari ^c   Fabre, Louis F ^d  

^a Therapeutic Services Inc   (United States)

^b S New Jersey Medical Institute   (United States)

^c Social Psychiatry Research Institute   (United States)

^d Fabre Research Clinic Inc   (United States)

Author keywords

Citalopram; Depression; Melancholia; Selective serotonin reuptake inhibitors; Serotonin

Indexed keywords

CHLORAL HYDRATE; CIPRAM; CITALOPRAM; CLOMIPRAMINE; FLUOXETINE; PLACEBO; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOSE CALCULATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG SCREENING; HUMAN; MAJOR CLINICAL STUDY; MELANCHOLIA; MULTICENTER STUDY; NAUSEA; OUTPATIENT CARE; PRIORITY JOURNAL; PSYCHOMOTOR RETARDATION; RANDOMIZED CONTROLLED TRIAL; SOMNOLENCE; TREATMENT OUTCOME; VERTIGO; XEROSTOMIA;

ADULT; CITALOPRAM; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE;

EID: 0032893212     PISSN: 10914269     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6394(1999)9:2<54::AID-DA2>3.0.CO;2-T     Document Type: Article

References (21)

1. American Psychiatric Association. 1980. Diagnostic and statistical manual of mental disorders, 3rd ed. Washington DC: American Psychiatric Association.
2. Baumann P, Larsen F. 1995. The pharmacokinetics of citalopram. Rev Contemp Pharmacother 6:287-295.
3. Bouchard JM, Delaunay J, Delisle J-P, Grasset N, Mermberg PF, Molczadzki M, Pagot R, Richou H, Robert G, Ropert R, Schuller E, Verdeau-Paillés J, Zarifian E, Høpfner Petersen HE. 1987. Citalopram versus maprotiline: a controlled, clinical multicenter trial in depressed patients. Acta Psychiatr Scand 76:583-592.
4. Danish University Antidepressant Group. 1986. Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicenter study. Psychopharmacology 90:131-138.
5. Danish University Antidepressant Group. 1990. Paroxetine: a selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study. J Affect Disord 18:289-299.
6. De Wilde J, Mertens C, Fredricson Overø K, Høpfner Petersen HE. 1985. Citalopram versus mianserin: a controlled, double-blind trial in depressed patients. Acta Psychiatr Scand 72:89-96.
7. Dencker SJ, Høpfner Petersen HE. 1989. Side-effect profile of citalopram and reference antidepressants in depression. In: Montgomery SA, editor. Citalopram, the new antidepressant from Lundbeck Research. Amsterdam, The Netherlands: Excerpta Medica. p 31-42.
8. Fredericson Overø K, Toft B, Chrostophersen L, Gylding-Sabroe JP. 1985. Kinetics of citalopram in elderly patients. Psychopharmacology 86:253-257.
9. Gravem A, Amthor KF, Astrup C, Elgen K, Gjessing LR, Gunby B, Pettersen RD, Kyrdalen L, Vaadel J, Øfsti E, Aarvold A. 1987. A double-blind comparison of citalopram (Lu 10-171) and amitriptyline in depressed patients. Acta Psychiatr Scand 75:478-486.
10. Hyttel J. 1982. Citalopram: pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry 6:277-295.
11. Hyttel J. 1994. Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs). Int Clin Psychopharmacol 9(1, suppl):19-26.
12. Lader M, Melhuish A, Frcka G, Fredricson Overø K, Christensen V. 1986. The effects of citalopram in single and repeated doses and with alcohol on physiological and psychological measures in healthy subjects. Eur J Clin Pharmacol 31:183-190.
13. Montgomery SA, Rasmussen JGC, Lyby K, Connor P, Tanghøj P. 1992. Dose response relationship of citalopram 20 mg, citalopram 40 mg and placebo in the treatment of moderate and severe depression. Int Clin Psychopharmacol 6:65-70.
14. Overø KF. 1982. Kinetics of citalopram in man: plasma levels in patients. Prog Neuropsychopharmacol Biol Psychiatry 6:311-318.
15. Oyehaug E, Ostensen ET, Salvesen B. 1984. High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients. J Chromatogr 308:199-208.
16. Patris M, Bouchard J-M, Bougerol T, Charbonnier J-F, Chevalier J-F, Clerc G, Cyran C, Van Amerongen P, Lemming O, Høpfner Petersen HE. 1996. Citralopram versus fluoxetine: a double-blind, controlled, multicentre, phase III trial in patients with unipolar major depression treated in general practice. Int Clin Psychopharmacol 11:129-136.
17. Perry PJ. 1996. Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. J Affect Disord 39:1-6.
18. Preskorn SH, von Moltke L, Alderman J, Harrison W, Chung M, Greenblatt D, Shader RI. 1993. In vitro and in vivo evaluations of the potential for desipramine interaction with fluoxetine or sertraline. In: New research program and abstracts of the 146th annual meeting of the American Psychiatric Association; May 23-26, San Francisco, CA. Abstract NR673:228.
19. Roose SP, Glassman AH, Attia E, Woodring S. 1994. Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia. Am J Psychiatry 151:1735-1739.
20. Rush AJ, Weissenburger JE. 1994. Melancholic symptom features and DSM-IV. Am J Psychiatry 151:489-498.
21. Stuppaeck CH, Geretsegger C, Whitworth AB, Schubert H, Platz, T, Konig P, Hinterhuber H, Felischhacer WW. 1994. A multicenter double-blind trial of paroxetine versus amitriptyline in depressed inpatients. J Clin Psychopharmacol 14:241-246.