Biphasic translocation of a 70 kDa heat shock protein in human cytomegalavirus-infected cells

Journal of General Virology

Volumn 80, Issue 1, 1999, Pages 63-68

  Ohgitani, Eriko ^a,b   Kobayashi, Kappei ^a   Takeshita, Kazushige ^a   Imanishi, Jiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Louis Pasteur Center for Medical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN; HEAT SHOCK PROTEIN 70; PHOSPHONOACETIC ACID; TUNICAMYCIN;

ARTICLE; CELL NUCLEUS; CYTOMEGALOVIRUS INFECTION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMEDIATE EARLY GENE; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALIA; CYTOMEGALOVIRUS; DNA VIRUSES; HUMAN HERPESVIRUS 5;

EID: 0032892182     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-80-1-63     Document Type: Article

References (26)

1. Brown, C. R., Martin, R. L., Hansen, W. J., Beckmann, R. P. & Welch, W. J. (1993). The constitutive and stress inducible forms of hsp 70 exhibit functional similarities and interact with one another in an ATP-dependent fashion. Journal of Cell Biology 120, 1101-1112.
2. Caswell, R., Hagemeier, C., Chiou, C.-J., Hayward, G., Kouzarides, T. & Sinclair, J. (1993). The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation. Journal of General Virology 74, 2691-2698.
3. Caswell, R., Bryant, L. & Sinclair, J. (1996). Human cytomegalovirus immediate-early 2 (IE2) protein can transactivate the human hsp70 promoter by alleviation of Dr1-mediated repression. Journal of Virology 70, 4028-4037.
4. Colberg, P. A., Santomenna, L. D., Harlow, P. P., Benfield, P. A. & Tenney, D. J. (1992). Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression. Journal of Virology 66, 95-105.
5. Collins, P. L. & Hightower, L. E. (1982). Newcastle disease virus stimulates the cellular accumulation of stress (heat shock) mRNAs and proteins. Journal of Virology 44, 703-707.
6. Cripe, T. P., Delos, S. E., Estes, P. A. & Garcea, R. L. (1995). In vivo and in vitro association of hsc70 with polyomavirus capsid proteins. Journal of Virology 69, 7807-7813.
7. Glick, B. S. (1995). Can hsp70 proteins act as force-generating motors? Cell 80, 11-14.
8. Hagemeier, C., Walker, S., Caswell, R., Kouzarides, T. & Sinclair, J. (1992a). The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID. Journal of Virology 66, 4452-4456.
9. Hagemeier, C., Walker, S. M., Sissons, P. J. G. & Sinclair, J. H. (1992b). The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements. Journal of General Virology 73, 2385-2393.
10. Jaattela, M. & Wissing, D. (1993). Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection. Journal of Experimental Medicine 177, 231-236.
11. Jaattela, M., Wissing, D., Bauer, P. A. & Li, G. C. (1992). Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. EMBO Journal 11, 3507-3512.
12. Jindal, S. & Young, R. A. (1992). Vaccinia virus infection induces a stress response that leads to association of Hsp70 with viral proteins. Journal of Virology 66, 5357-5362.
13. Kitay, K. K. & Rowe, D. T. (1996). Protein-protein interactions between Epstein-Barr virus nuclear antigen-LP and cellular gene products: binding of 70-kilodalton heat shock proteins. Virology 220, 91-99.
14. Kobayashi, K., Ohgitani, E., Tanaka, Y., Kita, M. & Imanishi, J. (1994). Herpes simplex virus-induced expression of 70 kDa heat shock protein (HSP70) requires early protein synthesis but not viral DNA replication. Microbiology and Immunology 38, 321-325.
15. Matsuo, M., Kaji, K., Utakoji, T. & Hosoda, K. (1982). Ploidy of human embryonic fibroblasts during in vitro aging. Journal of Gerontology 37, 33-37.
16. Morimoto, R. I. & Milarski, K. L. (1991). Expression and function of vertebrate hsp70 genes. In Stress Proteins in Biology and Medicine, pp. 323-360. Edited by R. I. Morimoto, A. Tissieres and C. Georgopoulos. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
17. Mosser, D. D., Caron, A. W., Bourget, L., Denis, L. C. & Massie, B. (1997). Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Molecular and Cellular Biology 17, 5317-5327.
18. Nevins, J. R. (1982). Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell 29, 913-919.
19. Notarianni, E. L. & Preston, C. M. (1982). Activation of cellular stress protein genes by herpes simplex virus temperature-sensitive mutants which overproduce immediate early polypeptides. Virology 123, 113-122.
20. Phillips, B., Abravaya, K. & Morimoto, R. I. (1991). Analysis of the specificity and mechanism of transcriptional activation of the human hsp70 gene during infection by DNA viruses. Journal of Virology 65, 5680-5692.
21. Radsak, K. D. & Weder, D. (1981). Effect of 2-deoxy-D-glucose on cytomegalovirus-induced DNA synthesis in human fibroblasts. Journal of General Virology 57, 33-42.
22. Santomenna, L. D. & Colberg, P. A. (1990). Induction of cellular hsp70 expression by human cytomegalovirus. Journal of Virology 64, 2033-2040.
23. Tenney, D. J., Santomenna, L. D., Goudie, K. B. & Colberg, P. A. (1993). The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression. Nucleic Acids Research 21, 2931-2937.
24. Welch, W. J. (1993). Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells. Philosophical Transactions of the Royal Society of London B Biological Sciences 339, 327-333.
25. Wiertz, E. J. H. J., Tortorella, D., Bogyo, M., Yu, J., Mothes, W., Jones, T. R., Rapoport, T. A. & Ploegh, H. L. (1996). Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 384, 432-438.
26. Zhu, H., Shen, Y. & Shenk, T. (1995). Human cytomegalovirus IE1 and IE2 proteins block apoptosis. Journal of Virology 69, 7960-7970.