A phage-displayed mimotope inhibits tumour necrosis factor-α-induced cytotoxicity more effectively than the free mimotope

Immunology

Volumn 96, Issue 1, 1999, Pages 109-113

  Chirinos Rojas, C L ^a   Steward, M W ^a   Partidos, Charalambos D ^b  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIOPHAGE; CELL STRAIN L 929; CYTOTOXICITY; DNA SEQUENCE; HUMAN; HUMAN CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

ANIMALS; ANTIGEN PRESENTATION; BACTERIOPHAGES; BINDING SITES; CYTOTOXICITY TESTS, IMMUNOLOGIC; EPITOPES; HUMANS; MICE; MOLECULAR MIMICRY; PEPTIDE LIBRARY; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA; SURFACE PLASMON RESONANCE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032891363     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1999.00660.x     Document Type: Article

References (20)

1. 1. BEUTLER B. & CERAMI A. (1989) The biology of cachectin/TNF-A primary mediator of the host response. Annu Rev Immunol 7, 625.
2. 2. TRACEY K.J. & CERAMI A. (1993) Tumor necrosis factor, other cytokines and disease. Annu Rev Biol 9, 317.
3. 3. MAINI R.N., ELLIOTT M.J., BRENNAN F.M. & FELDANN M. (1995) Beneficial effects of tumor necrosis alpha. Blockade in rheumatoid arthritis. Clin Exp Immunol 101, 207.
4. 4. ROSS S.E., WILLIAMS R.O., MASON L.J. et al. (1997) Suppression of TNFa expression, inhibition of Th1 activity and amelioration of collagen-induced arthritis by rolipran. J Immunol 159, 6253.
5. 5. WILLIAMS R.O., FELDMANN M. & MAINI R.N. (1992) Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 89, 9784.
6. 6. ELLIOTT M.J., MAINI R.N., FELDMANN M. et al. (1993) Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 36, 1681.
7. 7. BROCKHAUS M., SCHOENFELD H.J., SCHLAEGER E.J., HUNZIKER W., LESSLAUER W. & LOETSCHER H. (1990) Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc Natl Acad Sci USA 87, 3127.
8. 8. FOXWELL B., BARRET K. & FELDMANN M. (1990) Cytokine receptors: structure and signal transduction. Clin Exp Immunol 90, 161.
9. 9. WALDMANN T.A. (1991) Monoclonal antibodies in diagnosis and therapy. Science 252, 1657.
10. 10. MOHLER K.M., TORRANCE D.S., SMITH C.A. et al. (1993) Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 151, 1548.
11. 11. BANNER D.W., D'ARCY A., JAMES W. et al. (1993) Crystal structure of the soluble human 55 kDa TNF receptor human TNFbeta complex: implications for TNF receptor activation. Cell 73, 431.
12. 12. LAM K., SALMON K., HERSH E., HRUBY V., KAZMIERSKI W. & KNAPP R. (1991) A new type of synthetic peptide library for identifying ligand-binding activities. Nature 354, 82.
13. 13. SCOTT J.K. & SMITH G.P. (1990) Searching for peptide ligands with an epitope library. Science 249, 386.
14. 14. D'MELLO F., PARTIDOS C.D., STEWARD M.W. & HOWARD C.R. (1997) Definition of the primary structure of hepatitis B virus (HBV) PreS hepatocyte binding domain using random peptide libraries. Virology 237, 319.
15. 15. YANOFSKY S.D., BALDWIN D.N., BUTLER J.H. et al. (1996) High affinity type I interleukin 1 receptor antagonists discovered by screening recombinant peptide libraries. Proc Natl Acad Sci USA 93, 7381.
16. 16. PARTIDOS C.D., CHIRINOS-ROJAS C.L. & STEWARD M.W. (1997) The potential of combinatorial peptide libraries for the identification of inhibitors of TNFa-mediated cytotoxicity in vitro. Immunol Lett 57, 113.
17. 17. CHIRINOS-ROJAS C.L., STEWARD M.W. & PARTIDOS C.D. (1997) Use of a solid-phase random peptide library to identify inhibitors of TNFa-mediated cytotoxicity in vitro. Cytokine 9, 226.
18. 18. LEWIS M., TARTAGLIA L.A., LEE A. et al. (1991) Cloning and expression and cross-linking analysis of the murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci USA 88, 2830.
19. 19. DEMBIC Z., LOETSCHER H., GUBLER U. et al. (1990) Two human TNF receptors have similar extracellular but distinct intracellular domain sequences. Cytokine 2, 231.
20. 20. BUTLER D., SCALLON B., MEAGER A. et al. (1994) TNF receptor fusion proteins are effective inhibitors of TNF-mediated cytotoxicity on human KYM-1D4 rhabdomyosarcoma cells. Cytokine 6, 616.