Supernatants from co-cultured endothelial cells and syncytiotrophoblast microvillous membranes activate peripheral blood leukocytes in vitro

Human Reproduction

Volumn 14, Issue 4, 1999, Pages 919-924

  Von Dadelszen, Peter ^a,b   Hurst, Georgina ^a   Christopher, W G Redman ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Activation; Endothelium; Leukocyte; Pre eclampsia; Syncytiotrophoblast

Indexed keywords

CALCIUM ION; REACTIVE OXYGEN METABOLITE;

ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; HUMAN TISSUE; LEUKOCYTE ACTIVATION; LYMPHOCYTE; MICROVILLUS; MONOCYTE; PH; PLACENTA; PREECLAMPSIA; SUPERNATANT; SYNCYTIOTROPHOBLAST; TIME; UMBILICAL VEIN;

EID: 0032891211     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/14.4.919     Document Type: Article

References (27)

1. 2+ and intracellular acidification. Exp. Hematol, 24, 169-175.
2. Bain, B.J. and England, J.M. (1975) Variations in leucocyte count during menstrual cycle. Br. Med. J., 2, 473-475.
3. Barden, A., Graham, D., Beilin, L.J. et al. (1997) Neutrophil CD1 IB expression and neutrophil activation in pre-eclampsia. Clin. Sci. Colch., 92, 37-44.
4. Brumell, J.H., Burkhardt, A.L., Bolen, J.B. and Grinstein, S. (1996) Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils. J. Biol. Chem., 271, 1455-1461.
5. Busa, W.B. and Nuccitelli, R. (1984) Metabolic regulation via intracellular pH. Am. J. Physiol, 246, R409-R438.
6. Chua, S., Wilkins, T., Sargent, I.L. et al. (1991) Trophoblast deportation in pre-eclamptic pregnancy. Br. J. Obstet. Gynaecol., 98, 973-979.
7. Cockell, A.P., Learmont, J.G., Smârason, A.K. et al. (1997) Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function, ßr. J. Obstet. Gynaecol., 104, 235-240.
8. Goldstone, S.D., Fragonas, J-C., Jeitner, T.M. et al. (1995) Transcription factors as targets for oxidative signalling during lymphocyte activation. Biochim. Biophys. Acta, 1263, 114-122.
9. Himmelfarb, J., Hakim, R.M., Holbrook, D.G. et al. (1992) Détection of granulocyte reactive oxygen species formation in whole blood using flow cytometry. Cytometry, 13, 83-89.
10. Hubel, C.A., McLaughlin, M.K., Evans, R.W. et al. (1996) Fasting serum triglycérides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 h post partum. Am. J. Obstet. Gynecol, 174, 975-982.
11. Jaffe, E.A., Nachman, R.L., Becker, C.G. et al. (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologie criteria. J. Clin. Invest., 52, 2745-2756.
12. Knight, M., Redman, C.W.G., Linton.E.A. et al. (1998) Syncytiotrophoblast microvilli are shed into the maternal circulation in increased amounts in pre-eclamptic pregnancy. Br. J. Obstet. Gynaecol., 105, 632-640.
13. Mantovani, A. and Dejana, E. (1989) Cytokines as communication signals between leukocytes and endothelial cells. Immunol. Today, 10, 370-375.
14. Minta, A., Kao, J.P.Y. and Tsien, R.Y. (1989) Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J. Biol. Chem., 264, 8171-8178.
15. Rabesandratana, H., Fournier, A-M., Chateau, M-T. et al. (1992) Increased oxidative metabolism in PMA-activated lymphocytes: a flow cytometric study. Int. J. Immunophannac., 14, 895-902.
16. Rabinovitch, P.S. and June, C.H. (1994) Intracellular ionized calcium, magnesium, membrane potential, and pH. In Ormerod, M.G. (ed.), Flow Cytometry: A Practical Approach. Oxford University Press, Oxford, pp. 185-215.
17. Redman, C.W.G. (1991) The placenta and preeclampsia. Placenta, 12, 301-308.
18. Roberts, J.M., Taylor, R.N., Musci, T.J. et al. (1989) Preeclampsia: an endothelial cell disorder. Am. J. Obstet. Gynecol., 161, 1200-1204.
19. Sacks, G.P., Studena, K., Sargent, I.L. et al. (1998) Normal pregnancy and pre-eclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am. J. Obstet. Gynecol., 179, 80-86.
20. Schulung, G.A., Koiter, T.R. and Faas, M.M. (1997). Debate. Pre-eclampsia, why pre-eclampsia? Hum. Reprod., 12, 2087-2092.
21. Seeds, M.C., Parce, J.W., Szejda, P. et al. (1985) Independent stimulation of membrane potential changes and the oxidative metabolic burst in polymorphonuclear leukocytes. Blood, 65, 233-240.
22. Smârason, A.K., Sargent, I.L. and Redman, C.W.G. (1996) Endothelial cell proliferation is suppressed by plasma but not serum with preeclampsia. Am. J. Obstet. Gynecol., 174, 787-793.
23. Smârason, A.K., Sargent, I.L., Starkey, P.M. et al (1993) The effect of : placental Syncytiotrophoblast microvillous membranes from normal and pre-eclamptic women on the growth of endothelial cells in vitro. Br. J. Obstet. Gynaecol., 100, 943-949.
24. Smith, N.C., Brush, M.G. and Luckett, S. (1974) Preparation of human placental villous surface membrane. Nature, 252, 302-303.
25. Vmce, G.S., Starkey, P.M., Austgulen, R. et al. (1995) Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia. ßr. J. Obstet. Gynaecol., 102, 20-25.
26. von Dadelszen, P., Sargent, I.L., Jackson, M.C. and Redman, C.W.G. (1997) Increased intracellular calcium in maternal leukocytes in pre-eclampsia measured using Fluo-3 by flow cytometry [abstract], Hypertens. Pregn., 16, 300.
27. Zimmerman, O.A., Prescott, S.M. and Mclntyre, T.M. (1992) Endothelial cell interactions with granulocytes: tethering and signalling molecules. Immunol. Today, 13, 93-100.