Troglitazone not only reduced insulin resistance but also improved myotonia in a patient with myotonic dystrophy

European Neurology

Volumn 41, Issue 3, 1999, Pages 171-172

  Kashiwagi, Ken Ichiro ^a   Nagafuchi, Seiho ^a,b   Sekiguchi, Naotaka ^a   Yamagata, Akihiro ^a   Iwata, Isao ^a   Furuya, Hirokazu ^a   Kato, Motohiro ^a   Niho, Yoshiyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ORAL ANTIDIABETIC AGENT; TROGLITAZONE;

ADULT; ARTICLE; CASE REPORT; DIABETES MELLITUS; FEMALE; HUMAN; INSULIN RESISTANCE; MYOTONIA; MYOTONIC DYSTROPHY; PRIORITY JOURNAL;

EID: 0032891139     PISSN: 00143022     EISSN: None     Source Type: Journal    
DOI: 10.1159/000008045     Document Type: Article

References (7)

1. Brook JD, McCurrach ME, Harley HG, Buckler AJ, Church D, Aburatani H, Hunter K, Stanton VP, Thirion JP, Hudson T, et al: Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell 1992; 68:799-808.
2. Moxley RT, Corbett AJ, Minaker KL, Rowe JW: Whole body insulin resistance in myotonic dystrophy. Ann Neurol 1984;15:157-162.
3. Saltiel AR, Olefsky JM: Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 1996;45:1661-1669.
4. Inzucchi SE, Maggs DG, Spollett GR, Page AL, Rife FS, Walton V, Shulman GI: Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J Med 1998;338:867-872.
5. Mimura K, Umeda F, Hiramatsu S, Taniguchi S, Ono Y, Nakashima N, Kobayashi K, Masakado M, Sako Y, Nawata H: Effects of a new oral hypoglycaemic agent (CS-045) on metabolic abnormalities and insulin resistance in type 2 diabetes. Diab Med 1994;11:685-691.
6. Imano E, Kanda T, Kawamori R, Kajimoto Y, Yamasaki Y: Pioglitazone-reduced insulin resistance in patient with Werner syndrome. Lancet 1997; 350:1365.
7. Morrone A, Pegoraro E, Angelini C, Zammarchi E, Marconi G, Hoffman EP: RNA metabolism in myotonic dystrophy. J Clin Invest 1997;99:1691-1698.