Lymph node extraction of radiopaque nanoparticulates in the rabbit as measured in vivo with CT

Academic Radiology

Volumn 6, Issue 1, 1999, Pages 55-60

  Wolf, G L ^a   Shore, M T ^a   Bessin, G ^a   McIntire, G L ^a   Bacon, E R ^a   Illig, K J ^a  

^a NONE   (United States)

Author keywords

Computed tomography; In vivo physiology, rabbit; Percutaneous lymphography; Radiopaque nanoparticulates

Indexed keywords

(1 ETHOXYCARBONYL)PENTYL BIS(3,5 ACETYLAMINO) 2,4,6 TRIIODOBENZOIC ACID; CONTRAST MEDIUM; NANOPARTICLE; NC 67722; NC 68056; PLURONIC F 98; POLOXAMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DRUG ISOLATION; DRUG STRUCTURE; IN VIVO STUDY; LEG; LYMPH NODE; LYMPH VESSEL; LYMPHOGRAPHY; MASSAGE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0032890771     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1076-6332(99)80062-2     Document Type: Article

References (25)

1. Wolf GL Rogowska J Hanna GK Halpern EF Percutaneous CT lymphography with perflubron: imaging efficacy in rabbits and monkeys Radiology 191 1994 501 505
2. Wolf GL Gazelle GS McIntire GL Percutaneous computed tomography lymphography in the rabbit by subcutaneously injected nanoparticulates Acad Radiol 1 1994 352 357
3. Wolf GL Gazelle GS McIntire G Percutaneous computed tomographic lymphography of normal, inflamed, and cancerous nodes in the rabbit Invest Radiol 29 suppl 2 1994 S30 S32
4. Wolf GL Na GC Gazelle GS Time-lapse quantitative computed tomography lymphography: assessing lymphatic function in vivo Acad Radiol 1 1994 358 363
5. Wisner ER Katzberg RW Koblik PD Iodinated nanoparticles for indirect computed tomography lymphography of the craniocervical and thoracic lymph nodes in normal dogs Acad Radiol 1 1994 377 384
6. Wisner ER Katzberg RW Griffey SM Haley PJ Johnson DK Vessey AR Characterization of normal and cancerous lymph nodes on indirect computed tomography lymphographic studies after interstitial injection of iodinated nanoparticles Acad Radiol 3 suppl 2 1996 S257 S260
7. Wisner ER Katzberg RW Link DP Indirect computed tomography lymphography using iodinated nanoparticles to detect cancerous lymph nodes in a cutaneous melanoma model Acad Radiol 3 1996 40 48
8. Weissleder R Heautot JF Schaffer BK MR lymphography: study of a high-efficiency lymphotrophic agent Radiology 191 1994 225 230
9. Weissleder R Elizondo G Wittenberg J Lee AS Josephson L Brady TJ Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging Radiology 175 1990 494 498
10. Weissleder R Elizondo G Josephson L Experimental lymph node metastases: enhanced detection with MR lymphography Radiology 171 1989 835 839
11. (suppl) Misselwitz B Sachse A Interstitial MR lymphography using Gd-carrying liposomes Acta Radiol 412 1997 51 55
12. Elste V Wagner S Taupitz M Magnetic resonance lymphography in rats: effects of muscular activity and hyperthermia on the lymph node uptake of intravenously injected superparamagnetic iron oxide particles Acad Radiol 3 1996 660 666
13. Taupitz M Wagner S Hamm B Binder A Pfefferer D Interstitial MR lymphography with iron oxide particles: results in tumor-free and VX2 tumor-bearing rabbits AJR 161 1993 193 200
14. Taupitz M Wagner S Hamm B Dienemann D Lawaczeck R Wolf KJ MR lymphography using iron oxide particles: detection of lymph node metastases in the VX2 rabbit tumor model Acta Radiol 34 1993 10 15
15. Hamm B Taupitz M Hussmann P Wagner S Wolf KJ MR lymphography with iron oxide particles: dose-response studies and pulse sequence optimization in rabbits AJR 158 1992 183 190
16. US patent 5,322,679 Bacon ER Daum SJ Spara PP Iodinated aroyloxy esters June 21, 1994
17. US patent 5,145,684 Liversidge GG Cundy KC Bishop JF Czekai DA Surface modified drug nanoparticles September 8, 1992
18. US patent 5,318,767 Liversidge GG Cooper ER McIntire GL Shaw MJ X-ray contrast compositions useful in medical imaging June 7, 1994
19. (suppl) Wolf GL Rogowska J Gazelle GS Halpern EF Methods for quantitative CT lymphography Lymph 27 1994 261 264
20. Rogowska J Batchelder K Gazelle GS Halpern EF Connor W Wolf GL Evaluation of selected two-dimensional segmentation techniques for computed tomography quantitation of lymph nodes Invest Radiol 31 1996 138 145
21. Schmid-Schonbein GW Microlymphatics and lymph flow Physiol Rev 70 1990 987 1028
22. Ikomi F Hanna GK Schmid-Schonbein GW Mechanism of colloidal particulate uptake into the lymphatic system: basic study with percutaneous lymphography Radiology 196 1995 107 113
23. Trubetskoy VS Frank-Kamenetsky MD Whiteman KR Wolf GL Torchilin VP Stable polymeric micelles: a new lymphangiographic contrast media for gamma scintigraphy and MRI—preliminary report Acad Radiol 3 1996 232 238
24. Trubetskoy VS Whiteman KR Torchilin VP Wolf GL Massage-induced release of subcutaneously injected liposome-encapsulated drugs to the blood J Controll Release 50 1998 13 19
25. Hanna G Hopkins R Flaim K Leese P Schmid-Schonbein G Wolf GL Indirect lymphography with perflubron emulsion. Preclinical and clinical results Invest Radiol 29 suppl 2 1994 S33 S35