Receptor recognition by histidine 16 of human epidermal growth factor via hydrogen-bond donor/acceptor interactions

Journal of Cellular Biochemistry

Volumn 72, Issue 1, 1999, Pages 16-24

  Nandagopal, Krishnadas ^a   Terzaghi Howe, Margaret ^a   Niyogi, Salil K ^a,b  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Cell proliferation; Ligand receptor interaction; Protein engineering; Rational design; Tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HISTIDINE; IODINE 125; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; RECOMBINANT EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEIN;

ARTICLE; BINDING AFFINITY; CELL GROWTH; CELL PROLIFERATION; GENE EXPRESSION; HUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; RECEPTOR BINDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SITE DIRECTED MUTAGENESIS;

ANIMALS; BINDING, COMPETITIVE; CELL DIVISION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HISTIDINE; HUMANS; HYDROGEN BONDING; MUTAGENESIS, SITE-DIRECTED; MUTATION; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0032890433     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990101)72:1<16::AID-JCB3>3.0.CO;2-X     Document Type: Article

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