Conjugate additions of alkylchromium reagents mediated by chromium(III) chloride/manganese

Tetrahedron Letters

Volumn 40, Issue 1, 1999, Pages 67-70

  Augé, Jacques ^a   Gil, Richard ^a   Kalsey, Sophie ^a  

^a UNIVERSITÉ DE CERGY PONTOISE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM CHLORIDE; CHROMIUM DERIVATIVE; MANGANESE;

ARTICLE; CATALYSIS; CHEMICAL BINDING; CHEMICAL BOND; LIGAND BINDING; MOLECULAR INTERACTION; STRUCTURE ANALYSIS;

EID: 0032890213     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)80021-X     Document Type: Article

References (16)

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14. 3 (0.499g, 3.15 mmol) were put together and were stirring under nitrogen. THF (4 mL) was then added to the solid mixture. A solution of 4-tBuPy (0.925 mL, 6.3 mmol) in THF (5mL) was added dropwise to the suspension. To the resulting green solution were introduced acrylonitrile (0.398g, 7.5 mmol) and then benzyl bromide (0.257g, 1.5 mmol). After 13 h, the mixture was hydrolyzed with a solution of ammonium chloride, extracted with diethyl ether. The organic layers were washed with sodium hydrogen sulfate and sodium hydrogen carbonate solutions, then dried over magnesium sulfate. After evaporation, the residue was purified by chromotography on silica gel (cyclohexane/ ethyl acetate: 9/1) to afford 0.185g of the Michael adduct (85%).
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