Identification of a cis-acting element in the rat α-fetoprotein gene and its specific binding proteins in F9 cells during retinoic acid-induced differentiation

Journal of Cellular Biochemistry

Volumn 72, Issue 1, 1999, Pages 25-34

  Chen, Hongmin ^a,b   Dong, Jing Ming ^a,c   Liu, Yi ^a,d   Chiu, Jen Fu ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d Simons Center for Quantitative Biology   (United States)

Author keywords

AFP gene; Differentiation; F9 cells; Retinoic acid

Indexed keywords

ALPHA FETOPROTEIN; DNA FRAGMENT; MESSENGER RNA; PHOSPHORUS 32; RETINOIC ACID; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; GENE ACTIVATION; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; TERATOCARCINOMA;

ALPHA-FETOPROTEINS; ANIMALS; BINDING SITES; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; MICE; NUCLEAR PROTEINS; RATS; RECOMBINANT PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS; TRANSFECTION; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0032890173     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990101)72:1<25::AID-JCB4>3.0.CO;2-W     Document Type: Article

References (39)

1. Abelev GI. 1968. Production of embryonal serum alpha-globulin by hepatomas: review of experimental and clinical data. Cancer Res 28:1344-1350.
2. Adinolfi M. 1979. Human alphafetoprotein 1956-1978 [review]. Adv Hum Genet 9:165-228.
3. Artzt K, Dubois P, Bennett D, Condamine H, Babinet C, Jacob F. 1973. Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture. Proc Natl Acad Sci USA 70:2988-2992.
4. Bernier D, Thomassin H, Allard D, Guertin M, Hamel D, Blaquiere M, Beauchemin M, LaRue H, Estable-Puig M, Belanger L. 1993. Functional analysis of developmentally regulated chromatin-hypersensitive domains carrying the al-fetoprotein gene promoter and the albumin/alfetoprotein intergenic enhancer. Mol Cell Biol 13:1619-1633.
5. Chambon P. 1995. The molecular and genetic dissection of the retinoid signaling pathway. Recent Prog Hormone Res 50:317-332.
6. Chen H, Egan JO, Chiu JF. 1996. Regulation and activities of α-fetoprotein. Crit Rev Eukaryot Gene Exp 7:11-41.
7. Cook JR, Chiu JF. 1986. Mechanism of the dexamethasone effect on α-fetoprotein gene expression in McA-RH8994 rat hepatoma cells. J Biol Chem 262:4663-4668.
8. De Luca LM. 1991. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia [review]. FASEB J 5:2924-2933.
9. Dong JM, Nordloh PW, Chiu JF. 1989. The mechanism of the bidirectional regulation of the rat alpha-fetoprotein gene by glucocorticoid hormone. Mol Cell Endocrinol 66:109-114.
10. Feinberg AP, Vogelstein B. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13.
11. Glass CK, DiRenzo J, Kurokawa R, Han ZH. 1991. Regulation of gene expression by retinoic acid receptors [review]. DNA Cell Biol 10:623-638.
12. Godbout R, Ingram RS, Tilghman SM. 1988. Fine-structure mapping of the three mouse alpha-fetoprotein gene enhancers. Mol Cell Biol 8:1169-1178.
13. Godbout R, Tilghman SM. 1988. Configuration of the alpha-fetoprotein regulatory domain during development. Genes Dev 2:949-956.
14. Gorman CM, Moffat LF, Howard BM. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044-1051.
15. Hammer RE, Krumlanf R, Camper SA, Brinster RL, Tilghman SM. 1987. Diversity of alpha-fetoprotein gene expression in mice generated by a combination of separate enhancer elements. Science 235:53-58.
16. LaRosa GJ, Gudas, LJ. 1988. Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox. Mol Cell Biol 8:3906-3917.
17. Liu Y, Chiu JF. 1994. Transactivation and repression of the alpha-fetoprotein gene promoter by retinoid X receptor and chicken ovalbumin upstream promoter transcription factor. Nucleic Acids Res 22:1079-1086.
18. Liu Y, Chen H, Chiu JF. 1994a. Identification of a retinoic acid response element upstream of the rat alpha-fetoprotein gene. Mol Cell Endocrinol 103:149-156.
19. Liu Y, Chen H, Dong JM, Chiu JF. 1994b. cis-acting elements in 5′-flanking region of rat alpha-fetoprotein mediating retinoic acid responsiveness. Biochem Biophys Res Commun 205:700-705.
20. Mangelsdorf DJ, Evans RM. 1995. The RXR heterodimers and orphan receptors. Cell 83:841-850.
21. Means AL, Gudas LJ. 1995. The roles of retinoids in vertebrate development. Annu Rev Biochem 64:201-233.
22. Martin CA, Ziegler LM, Napoli JL. 1990. Retinoic acid, dibutyryl-cAMP, and differentiation affect the expression of retinoic acid receptors in F9 cells. Proc Natl Acad Sci USA 87:4804-4808.
23. Muglia L, Rothman-Denes LB. 1986. Cell type-specific negative regulatory element in the control region of the rat alpha-fetoprotein gene. Proc Natl Acad Sci USA 83:7653-7657.
24. Murphy SP, Garbern Odenwald WF, Lazzarini RA, Linney E. 1988. Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells. Proc Natl Acad Sci USA 85:5587-5591.
25. Millonig JH, Emerson JA, Levorse JM, Tilghman SM. 1995. Molecular analysis of the distal enhancer of the mouse alpha-fetoprotein genes. Mol Cell Biol 15:3848-3856.
26. Ruoslahti E. 1979. alpha-Fetoprotein in cancer and fetal development [review]. Adv Cancer Res 29:275-346.
27. nd eds. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
28. Scott RW, F. Vogt TF, Croke ME, Tilghman SM. 1984. Tissue-specific activation of a cloned alpha-fetoprotein gene during differentiation of a transfected embryonal carcinoma cell line. Nature 310:562-567.
29. Silver LM, Martin GR, Strickland S. 1983. Teratocarcinoma stem cells. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
30. Soprano DR, Soprano KJ, Wyatt ML, Goodman DS. 1988. Induction of the expression of retinol-binding protein and transthyretin in F9 embryonal carcinoma cells differentiated to embryoid bodies. J Biol Chem 263:17897-17900.
31. Strickland S, Mahdavi V. 1978. The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell 15:393-403.
32. Thomas PS. 1980. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci USA 77:5201-5205.
33. Tilghman SM. 1985. The structure and regulation of the alpha-fetoprotein and albumin genes [review]. Oxf Surv Eukaryot Genes 2:160-206.
34. Vacher J, Tilghman SM. 1990. Dominant negative regulation of the mouse alpha-fetoprotein gene in adult liver. Science 250:1732-1735.
35. Wahli W, Martinez E. 1991. Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression [review]. FASEB J 5:2243-2249.
36. Wen P, Groupp ER, Buzard G, Crawford N, Locker J. 1991. Enhancer, repressor, and promoter specificities combine to regulate the rat alpha-fetoprotein gene. DNA Cell Biol 10:525-536.
37. Widen SG, Papaconstantinou J. 1986. Liver-specific expression of the mouse alpha-fetoprotein gene is mediated by cis-acting DNA elements. Proc Natl Acad Sci USA 83:8196-8200.
38. Wissmann A, Hillen W. 1991. DNA contacts probed by modification protection and interference studies. Methods Enzymol 208:365-379.
39. Zhang XK, Dong JM, Chiu JF. 1991. Regulation of alphafetoprotein gene expression by antagonism between AP-1 and the glucocorticoid receptor at their overlapping binding site. J Biol Chem 266:8248-8254.