The effect of vitamin K and D supplementation on ovariectomy-induced bone loss

Calcified Tissue International

Volumn 65, Issue 4, 1999, Pages 285-289

  Matsunaga, S ^a   Ito, H ^a   Sakou, T ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Activated vitamin D3; Menaquinone; Microradiography; Ovariectomy

Indexed keywords

COLECALCIFEROL; MENAQUINONE; VITAMIN D; VITAMIN K GROUP;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE ATROPHY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HISTOLOGY; MICRORADIOGRAPHY; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; RAT; TRABECULAR BONE; VITAMIN SUPPLEMENTATION;

ANIMALS; DIETARY SUPPLEMENTS; FEMALE; HYDROXYCHOLECALCIFEROLS; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; TIBIA; VITAMIN K;

EID: 0032888605     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900700     Document Type: Article

References (43)

1. Hart JP, Shearer MJ, Klenerman L, Catterall A, Reeve J, Sambrook PN, Dodds RA, Bitensky L, Chayen J (1985) Electrochemical detection of depressed circulating levels of vitamin K1 in osteoporosis. J Clin Endocrinol Metab 60:1268-1269
2. Hodges SJ, Akesson K, Vergnaud P, Obrant K, Delmas PD (1993) Circulating levels of vitamins K1 and K2 decreased in elderly women with hip fracture. J Bone Miner Res 8:1241-1245
3. Akiyama Y, Hara K, Ohkawa I, Tajima T (1993) Effects of menatetrenone on bone loss induced by ovariectomy in rats. Jpn J Pharmacol 62:145-153
4. Koshihara Y, Hoshi K (1997) Vitamin K2 enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. J Bone Miner Res 12:431-438
5. Weinstein RS, Underwood JL, Huston MS, deLuca HF (1984) Bone histomorphometry in vitamin D-dependent rats infused with calcium and phosphorus. Am J Physiol 246:499-505
6. 3, parathyroid hormone, and glucocorticoids. Met Bone Dis Rel Res 5:229-234
7. Lian J, Stewart C, Puchacz E, Mackowiak S, Shalhoub V, Collart D, Zambetti G, Stein G (1989) Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA 86:1143-1147
8. Hara K, Akiyama Y, Tomiuga T, Kobayashi M, Nakamura T, Tajima T (1994) Influence of vitamin D3 on inhibitory effect of vitamin K2 on bone loss in ovariectomized rats. Folia Pharmacol Jpn 104:101-109
9. Jee WSS, Inoue J, Jee KW, Haba T (1983) Histomorphometric assay of the growing long bone. In Takahashi H (ed) Handbook of bone morphology. Nishimura Co. Ltd., Niigata, Japan, pp 101-122
10. Jee WSS, Smith JM (1985) Image analysis of calcified tissue. In Dickson GR (ed) Methods of calcified tissue preparation. Elsevier, Amsterdam, pp 673-696
11. Dam H (1935) The antihaemmorrhagic vitamin of the chick. Nature 135:652-653
12. Stenflo J, Fernlund P, Egan W, Roepstorff P (1974) Vitamin K-dependent modification of glutamic acid residues in prothrombin. Proc Natl Acad Sci USA 71:2730-2733
13. Olson RE, Suttie JW (1977) Vitamin K and γ-carboxyglutamate biosynthesis. Vitam Horm 35:59-108
14. Esmon CT, Sadowski JA, Suttie JW (1975) A new carboxylation reaction. The vitamin K-dependent incorporation of H14Co3-into prothrombin. J Biol Chem 250:4744-4748
15. Hauschka PV, Lian JB, Gallop PM (1975) Direct identification of the calcium-binding amino acid, γ-carboxyglutamate, in mineralized tissue. Proc Natl Acad Sci USA 72:3925-3929
16. Celeste AJ, Rosen V, Buecker JL, Kriz R, Wang EA, Wozney JM (1986) Isolation of human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J 5:185-1890
17. Price PA, Otsuka AS, Poser JW, Kristaponis J, Raman N (1976) Characterization of a γ-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci USA 73:1447-1451
18. Price PA, Poser JW, Raman N (1976) Primary structure of the γ-carboxyglutamic acid-containing protein from bovine bone. Proc Natl Acad Sci USA 73:3374-3375
19. Hauschka PV, Carr SA (1982) Calcium-dependent α-helical structure in osteocalcin. Biochemistry 21:2538-2547
20. Price PA (1989) Gla-containing proteins of bone. Connect Tissue Res 21:51-60
21. Nishimoto SK, Price PA (1985) The vitamin K-dependent bone protein is accumulated within cultured osteosarcoma cells in the presence of the vitamin K antagonist warfarin. J Biol Chem 260:2832-2836
22. Price PA, Baukol BE (1980) 1,25 (OH)2D3 increases the synthesis of the vitamin K-dependent bone protein by osteosarcoma cells. J Biol Chem 225:1660-1663
23. Akiyama Y, Hara K, Tajima T, Murota S, Morita I (1994) Effect of vitamin K2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures. Eur J Pharmacol 263:181-185
24. Notoya K, Yoshida K, Shirakawa Y, Taketomi S, Tsuda M (1995) Similarities and differences between the effects of ipriflavone and vitamin K on bone resorption and formation in vitro. Bone 16:349-353
25. Hara K, Akiyama Y, Nakamura T, Murota S, Morita I (1995) The inhibitory effect of vitamin K2 (menatetrenone) on bone resorption may be related to its side chain. Bone 16:179-184
26. Hara K, Akiyama Y, Tajima T, Shiraki M (1993) Menatetrenone inhibits bone resorption partly through inhibition of PGE2 synthesis in vitro. J Bone Miner Res 8:535-542
27. 2 modulates proliferation and function of osteoblastic cells in vitro. Biochem Biophys Res Commun 187:814-820
28. Knapen MHJ, Hamulyak K, Vermeer C (1989) The effect of vitamin K supplementation on circulating osteocalcin (bone Gla protein) and urinary calcium excretion. Ann Intern Med 111:1001-1005
29. Plantalech L, Guillaumont M, Vergnaud P, Leclercp M, Delmas PD (1991) Impairment of gamma carboxylation of circulating osteocalcin (bone Gla protein) in elderly women. J Bone Miner Res 6:1211-1216
30. Douglas AS, Robins SP, Hutchison JD, Porter RW, Stewart A, Reid DM (1995) Carboxylation of osteocalcin in postmenopausal osteoporotic women following vitamin K and D supplementation. Bone 17:15-20
31. Fiore CE, Tamburino C, Foti R, Grimaldi D (1990) Reduced bone mineral content in patients taking an oral anticoagulant. South Med J 83:538-542
32. Resch H, Pietschmann P, Krexner E, Willvonseder R (1991) Decreased peripheral bone mineral content in patients under anticoagulant therapy with phenprocoumon. Eur Heart J 12: 439-441
33. Bouckaert JH (1960) Fracture healing by vitamin K. Nature 19:849
34. Szulic P, Chapuy MC, Meunier PJ, Delmas PD (1993) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest 91:1769-1774
35. Orimo H, Shiraki M, Fujitas TY, Onomura T, Inoue T, Kushida K (1992) Clinical evaluation of menatetrenone in the treatment of involutional osteoporosis. A double-blind multicenter comparative study with 1 α-hydroxyvitamin D3. J Bone Miner Res 7 (suppl 1) S:122
36. Morrison NA, Shine J, Fragonas JC, Verkest V, Eisman JA (1989) 1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene. Science 246: 1158-1161
37. Sergeev IN, Spirichev VB (1989) Do 1,25-dihydroxy vitamin D3 receptors depend on vitamin K? Nutr Res 9:725-733
38. Mueller KH, Trias A, Ray RD (1969) Bone density and composition. Age-related and pathological changes in water and mineral content. J Bone Joint Surg 48A:138-148
39. Kimmel DB, Wronski TJ (1990) Nondestructive measurement of bone mineral in femurs from ovariectomized rats. Calcif Tissue Int 46:101-110
40. Li XJ, Jee WSS, Ke HZ, Mori S, Akamine T (1991) Agerelated changes of cancellous and cortical bone histomorphometry in female Sprague-Dawley rats. Cells Materials (suppl) 1:25-35
41. Peng ZQ, Vaananen HK, Zhang HX, Tuukkanen J (1995) Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone. Bone 20:207-212
42. Miller SC, Bowman BM, Jee WSS (1995) Available animal models of osteopenia - small and large. Bone 17:117S-123S
43. Wronski TJ, Yen CF (1991) The ovariectomized rat as an animal model for postmenopausal bone loss. Cells Mater (suppl) 1:69-74