Stereoselective Michael addition of glycine anions to chiral fischer alkenylcarbene complexes. Asymmetric synthesis of β-substituted glutamic acids

Journal of Organic Chemistry

Volumn 64, Issue 18, 1999, Pages 6554-6565

  Ezquerra, Jesús ^a   Pedregal, Concepción ^a   Merino, Isabel ^b   Flórez, Josefa ^b   Barluenga, José ^b   García Granda, Santiago ^b   Llorca, María Amparo ^b  

^a ELI LILLY AND COMPANY   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID DERIVATIVE; GLYCINE;

AMINO ACID SYNTHESIS; ARTICLE; CHIRALITY; COMPLEX FORMATION; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0032888523     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9819739     Document Type: Article

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88. -3 in 6 M HCl) = +11.1.
89. -3 in 6 M HCl) = +19.15.