Concentrations of free carnosine (a putative membrane-protective antioxidant) in human muscle biopsies and rat muscles

Archives of Gerontology and Geriatrics

Volumn 29, Issue 2, 1999, Pages 107-113

  Stuerenburg, Hans Joerg ^a   Kunze, Klaus ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Amyotrophic lateral sclerosis; Antioxidant; Carnosine; Membrane protection; Neuromuscular diseases

Indexed keywords

ANTIOXIDANT; CARNOSINE;

AGING; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG MECHANISM; HUMAN; HUMAN TISSUE; MUSCLE BIOPSY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; TISSUE LEVEL;

EID: 0032887268     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4943(99)00020-5     Document Type: Article

References (26)

1. Aruoma O.I., Lauchton M.J., Halliweil B. Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo? Biochem. J. 264:1989;863-869.
2. Bauer K., Schulz M. Biosynthesis of carnosine and related peptides by skeletal muscle cells in primary culture. Eur. J. Biochem. 219:1994;43-47.
3. Blazejowski C.A., Webster G.C. Effect of age on peptide chain initiation and elongation in preparations from brain, liver, kidney and skeletal muscle of the C57B1/6J mouse. Mech. Age. Dev. 25:1984;323-333.
4. Boldyrev A.A., Petukhov V.B. Localization of carnosine effect on the fatigued muscle preparation. Gen. Pharmacol. 9:1978;17-20.
5. Boldyrev A.A., Severin S.E. The histamine-containing dipeptides carnosine and ansrine: distribution, properties, and biological significance. Adv. Enzyme Reg. 30:1990;175-194.
6. Chan W.K., Decker E.A., Chow C.K., Boissonneault G.A. Effect of dietary carnosine on plasma and tissue antioxidant concentration and on lipid oxidation in rat skeletal muscle. Lipids. 29:1994;461-466.
7. Chasovnikova L.V., Formazyuk V.E., Sergienko V.l., Boldirev A.A., Severin S.E. The antioxidative properties of carnosine and some drugs. Biochem. Int. 20:1990;1097-1103.
8. Crush K.G. Carnosine and related substances in animal tissues. Comp. Biochem. Physiol. 34:1970;3-30.
9. Drachman, D.A., Long, R.R., 1984. Neurological evaluation of the elderly patient. In: Albert, M.L. (Ed.), Clinical Neurology Of Aging, Oxford University Press, New York, pp. 97-113.
10. Gulyaeva N.V., Obidin A.B., Marinov B.S. Modulation of superoxide dismutase by electron donors and acceptors. FEBS Lett. 221:1988;211-214.
11. Gulyaeva N.V., Obidin A.B., Levshina I.P., Filonenko A.M., Dupin A.M., Boldyrev A.A. Effect of carnosine on free radical oxidation of lipids in rats under acute stress. Biol. Nauki. 8:1989;5-16. In Russian.
12. Harris R.C., Hultman E., Nordesjo L.O. Glycogen. glycolytic intermediates and highenergy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand. J. Clin. Lab. Invest. 33:1974;109-120.
13. Hartman P.E., Hartman Z., Ault K.T. Scavenging of singlet molecular oxygen by imidazole compounds: high and sustained activities of carboxy terminal histidine dipeptides and exceptional activity of imidazole-4-acetic acid. Photochem. Photobiol. 51:1990;59-66.
14. Isichenko N.A., Filippova E.N. Pharmacological research on anserine. Farmakol. Toksikol. 2:1939;32-37. In Russian.
15. Johnson P., Hammer J.L. Histidine dipeptide levels in ageing and hypertensive rat skeletal and cardiac muscles. Comp. Biochem. Physiol. 103:1992;981-984.
16. Kohen R., Yamamoto Y., Cundy K.C., Ames B.N. Antioxydant activity of carnosine, homocarnosine and anserine present in muscle and brain. Proc. Natl. Acad. Sci. USA. 85:1988;3175-3179.
17. Lamont C., Miller D.J. Calcium sensitizing action of carnosine and other endogenous imidazoles in chemically skinned striated muscle. J. Physiol. 454:1992;421-434.
18. Mannion A.F., Jakeman P.M., Dunnett M., Harris R.C., Willan P.L. Carnosine ens anserine concentrations in the quadriceps femoris muscle of healthy humans. Europ. J. Appl. Physiol. Occup. Physiol. 64:1992;47-50.
19. Marlin D.J., Harris R.C., Gash S.P., Snow D.H. Carnosine content of the middle gluteal muscle in thoroughbred horses with relation to age, sex and training. Comp. Biochem. Physiol. 93:1989;629-632.
20. Nagai K., Suda T. Realization of spontaneous healing function by carnosine. Methods Findings Exp. Clin. Pharmacol. 10:1988;497-507.
21. Pluskal M.G., Moreyra M., Burini R.C., Young V.R. Protein synthesis studies in skeletal muscle of aging rats. I: Alterations in nitrogen composition and protein synthesis using a crude polyribosome and pH 5 enzymes system. J. Gerontol. 39:1984;385-391.
22. Severin, S.E. 1964. Problems concerned with the biological activity of naturally occuring imidazole compounds. Proc. Plenary Sessions 6th Int. Congr. Biochemistry, New York, pp. 45-61.
23. Severin S.E., Kirzon M.V., Kaftanova T.M. Effects of carnosine and anserine on the activity of isolated frog muscle. Doklady Akademli Nauk. SSSR. 91:1953;691-694. In Russian.
24. Stuerenburg H.J., Kunze K. Tissue concentrations of nerve growth factor in aging rat heart and skeletal muscle. Muscle Nerve. 21:1998;404-406.
25. Stuerenburg H.J., Jung R., Kunze K. Age effects on growth hormone and testosterone responses to endurance exercise in patients with neuromuscular diseases. Arch. Geront. Geriat. 28:1999;45-51.
26. Wolfson L.I., Katzmann R. The neurological consultation at age 80. Katzman R., Terry A.D. The Neurology Of Aging. 1983;221-244 Davis, Philadelphia.