Influence of non-ionic surfactants, pH and propylene glycol on percutaneous absorption of piroxicam from cataplasm

International Journal of Pharmaceutics

Volumn 186, Issue 2, 1999, Pages 141-148

  Okuyama, H ^a,b   Ikeda, Y ^a   Kasai, S ^a   Imamori, K ^a   Takayama, K ^b   Nagai, T ^b  

^a SSP CO LTD   (Japan)

^b HOSHI UNIVERSITY   (Japan)

Author keywords

Percutaneous absorption; pH; Piroxicam; Polyoxyethylene non ionic surfactant; Propylene glycol; Topical preparation

Indexed keywords

GLYCEROL; KAOLIN; NONIONIC SURFACTANT; PIROXICAM; POLYOXYETHYLENE; PROPYLENE GLYCOL; SORBITOL;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FORMULATION; GUINEA PIG; MALE; NONHUMAN; PH; PRIORITY JOURNAL; SKIN ABSORPTION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCIPIENTS; GUINEA PIGS; HYDROGEN-ION CONCENTRATION; MALE; MUSCLE, SKELETAL; PIROXICAM; PROPYLENE GLYCOLS; SKIN ABSORPTION; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE-ACTIVE AGENTS;

EID: 0032886588     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00154-4     Document Type: Article

References (19)

1. Bendas B., Schmalß U., Neubert R. Influence of propylene glycol as cosolvent on mechanisms of drug transport from hydrogels. Int. J. Pharm. 116:1995;19-30.
2. Dalvi U., Zatz J. Effect of non ionic surfactants on penetration of dissolved benzocaine through hairless mouse skin. J. Soc. Cosmet. Chem. 32:1981;87-94.
3. Endo M., Yamamoto T., Ijuin T. Effect of non ionic surfactants on the percutaneous absorption of tenoxicam. Chem. Pharm. Bull. 44:1996;865-867.
4. Flynn G.L. Topical drug absorption and topical pharmaceutical systems. Banker G.S., Rhodes C.T. Modern Pharmaceutics. 2nd ed:1989;263-325 Marcel Dekker, New York.
5. Grahame R. Transdermal non-steroidal anti-inflammatory agents. Br. J. Clin. Pract. 49:1995;33-35.
6. Guy R., Maibach H. Drug delivery to local subcutaneous structures following topical administration. J. Pharm. Sci. 72:1983;1375-1380.
7. Herzfeldt C., Kümel R. Dissociation constants, solubilities and dissolution rates of some selected non-steroidal antiinflammatories. Drug Dev. Ind. Pharm. 9:1983;767-793.
8. Inoki R., Kudo T., Ohno H., Kohda T., Ogawa Y., Mizuno H., Isomae K., Ohkawa J. Basal pharmacological action of indomethacin-containing poultice. Ther. Res. 3:1985;95-101.
9. Iwasa A., Irimoto K., Kasai S., Okuyama H., Nagai T. Effect of non ionic surfactants on percutaneous absorption of diclofenac Na. J. Pharm. Sci. Technol. Jpn. 51:1991;16-21.
10. McNeill S., Potts R., Francoeur M. Local enhanced topical delivery (LETD) of drugs: does it truly exist? Pharm. Res. 9:1992;1422-1427.
11. Mizushima Y. Recent advances in non-steroid anti-inflammatory drugs. Drugs Exptl. Clin. Res. XIII:1987;689-693.
12. Nishiyama T., Iwata Y., Nakajima K., Mitsui T. In vivo percutaneous absorption of polyoxyethylene lauryl ether surfactants in hairless mice. J. Soc. Cosmet. Chem. 34:1983;263-271.
13. Obata Y., Takayama K., Maitani Y., Machida Y., Nagai T. Effect of ethanol on skin permeation of nonionized and ionized diclofenac. Int. J. Pharm. 89:1993;191-198.
14. Santoyo S., Arellano A., Ygartua P., Martín C. Penetration enhancer effects on the in vitro percutaneous absorption of piroxicam through rat skin. Int. J. Pharm. 117:1995;219-224.
15. Sarpotdar P., Zatz J. Evaluation of penetration enhancement of lidocaine by non-ionic surfactants through hairless mouse skin in vitro. J. Pharm. Sci. 75:1986;176-181.
16. Schiantarelli P., Acerbi D., Bovis G. Some pharmacokinetic properties and bioavailability by oral and rectal route of piroxicam in rodents and in man. Arzneim.-Forsch. Drug Res. 31:1981;92-97.
17. Schiantarelli P., Cadel S., Acerbi D., Pavesi L. Antiinflammatory activity and bioavailability of percutaneous piroxicam. Arzneim.-Forsch. Drug Res. 32:1982;230-235.
18. Wada Y., Etoh Y., Ohita A., Kimata H., Koide T., Ishihama H., Mishima Y. Percutaneous absorption and anti-inflammatory activity of indomethacin in ointment. J. Pharm. Pharmacol. 34:1982;467-468.
19. Walters K., Olejink O.J. Effects of non-ionic surfactants on the hairless mouse skin penetration of methyl nicotinate. Pharm. Pharmacol. 35(Suppl.):1983;79.