Retinyl palmitate supplementation by inhalation of an aerosol improves vitamin A status of preschool children in Gondar (Ethiopia)

British Journal of Nutrition

Volumn 82, Issue 3, 1999, Pages 179-182

  Biesalski, Hans ^a   Reifen, Ram ^b   Fürst, Peter ^a   Edris, Melkie ^c  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF GONDAR   (Ethiopia)

Author keywords

Retinyl palmitate; Vitamin A; Xerophthalmia

Indexed keywords

RETINOL; RETINOL BINDING PROTEIN; RETINOL PALMITATE;

AEROSOL; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ETHIOPIA; HUMAN; INHALATIONAL DRUG ADMINISTRATION; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; RETINOL DEFICIENCY; VITAMIN BLOOD LEVEL;

EID: 0032886477     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1017/s000711459900135x     Document Type: Article

References (26)

1. Bhandari N, Bhan MK & Sazawal S (1994) Impact of massive dose of vitamin A given to preschool children with acute diarrhoea on subsequent respiratory and diarrhoea morbidity. British Medical Journal 309, 1404-1407.
2. Biesalski HK (1996) Effects of intra-tracheal application of vitamin A on concentrations of retinol derivatives in plasma, lungs and selected tissues of rats. International Journal of Vitamin and Nutrition Research 66, 106-112.
3. Biesalski HK, Ehrenthal W, Gross M & Hafner G (1983) Rapid determination of retinol (vitamin A) in serum by high pressure liquid chromatography (HPLC). International Journal of Vitamin and Nutrition Research 53, 130-136.
4. Biesalski HK, Frank J, Beck C, Seeliger MW, Wissinger B, Reifen R & Zrenner E (1999) Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol-binding protein. American Journal of Clinical Nutrition 69, 931-936.
5. Biesalski HK & Stofft E (1992) Biochemical, morphological and functional aspects of systemic and local vitamin A-deficiency in the respiratory tract. Annals of the New York Academy of Sciences 669, 678-686.
6. Biesalski HK & Weiser H (1990) Microdetermination of retinyl esters in Guinea pig tissues under different vitamin A-status conditions. Micronutrient Analysis 7, 97-116.
7. Biesalski HK, Wellner U & Weiser H (1990) Increased noise susceptibility during vitamin A deficiency in guinea pigs. Journal of Nutrition 120, 726-737.
8. Blaner WS (1989) Retinol-binding protein: the serum transport protein for vitamin A. Endocrinology Reviews 10, 308-316.
9. DeSole G, Belay Y & Zegeye B (1987) Vitamin A deficiency in Southern Ethiopia. American Journal of Clinical Nutrition 45, 780-784.
10. Gerlach T, Biesalski HK, Weiser H, Haeussermann B & Baessler KH (1989) Vitamin A in parenteral nutrition: uptake and distribution of retinyl esters after intravenous application. American Journal of Clinical Nutrition 50, 1029-1038.
11. Hultin M, Savonen R & Olivecrona T (1996) Chylomicron metabolism in rats: lipolysis, recirculation of triglyceride derived fatty acids in plasma FFA, and fate of core lipids as analyzed by compartmental modelling. Journal of Lipid Research 37, 1022-1036.
12. Humphrey JH, Agoestina T, Wu L, Usman A, Nurachim M, Subardja D, Hidayat S, Tielsch J, West KP & Sommer A (1996) Impact of neonatal vitamin A supplementation on infant morbidity and mortality. Journal of Pediatrics 128, 489-496.
13. McGowan SE, Doro MM & Jackson S (1997) Endogenous retinoids increase perinatal elastin gene expression in rat lung fibroblasts and fetal explants. American Journal of Physiology 273, L410-L416.
14. Napoli J (1996) Retinoic acid biosynthesis and metabolism. FASEB Journal 10, 993-1001.
15. Napoli JL, Pacia EB & Salerno GJ (1989) Cholate effects on all trans retinyl-palmitate hydrolysis in tissue homogenates: solubilization of multiple kidney membrane hydrolases. Archives of Biochemistry and Biophysics 274, 192-199.
16. Rahman MM, Mahalanabis D, Alvarez JO, Wahed MA, Islam MA, Habte D & Khaled MA (1996) Acute respiratory infections prevent improvement of vitamin A status in young infants supplemented with vitamin A. Journal of Nutrition 126, 628-633.
17. Rahmathullah L, Underwood BA, Thulasiraj RD & Milton RC (1991) Diarrhea, respiratory infections and growth are not affected by a weekly low-dose vitamin A supplement: a masked, controlled field trial in children in Southern India. American Journal of Clinical Nutrition 54, 568-577.
18. Ramakrishnan U, Latham MC & Abel R (1995a) Vitamin A supplementation does not improve growth of preschool children: a randomized, double-blind field trial in South India. Journal of Nutrition 125, 202-211.
19. Ramakrishnan U, Latham MC, Abel R & Frongillo EA Jr (1995b) Vitamin A supplementation and morbidity among preschool children in South India. American Journal of Clinical Nutrition 61, 1295-1303.
20. Roche N, Chinet T & Huchon G (1997) Ambulatory inhalation therapy in obstructive lung diseases. Respiration 64, 121-130.
21. Seeliger MW, Biesalski HK, Wissinger B, Gollnick H, Gielen S, Frank J, Beck S & Zrenner E (1999) Phenotype in retinol deficiency due to hereditary defect in retinol binding protein synthesis. Investigative Opthalmology and Visual Sciences 40, 3-11.
22. Simm K (1980) Klinische Erprobung von Coldastop bei Rhinitis sicca, Nasentropenabusus und postoperativen pathologischen Heilungsverläufen (Clinical test of Coldastop in rhinitis sicca, nasal drop abuse and pathological postoperative healing). Therapie Woche 30, 8002-8003.
23. Sommer A, Katz J & Tarwatjo I (1984) Increased risk of respiratory disease and diarrhea in children with preexisting mild vitamin A deficiency. American Journal of Clinical Nutrition 40, 1090-1095.
24. Sommer A, Rarwotjo I & Katz J (1986) Increased risk of xerophthalmia following diarrhea and respiratory disease. American Journal of Clinical Nutrition 45, 977-980.
25. Stofft E, Biesalski HK, Niederauer U, Zschäbitz A & Weiser H (1992) Morphological changes in the tracheal epithelium of guinea pigs in conditions of "acute" vitamin A deficiency. International Journal of Vitamin and Nutrition Research 62, 143-147.
26. World Health Organization (1984) Prevention and Control of Vitamin A Deficiency and Xerophthalmia. WHO 37th World Health Assembly, Agenda Item 20.A37/A. Conference Paper no. 6. Geneva: WHO.