Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation

Journal of Thoracic and Cardiovascular Surgery

Volumn 118, Issue 3, 1999, Pages 460-466

  Rinder, C S ^a   Rinder, H M ^a   Smith, M J ^a   Tracey, J B ^a   Fitch, J ^a   Li, L ^a   Rollins, S A ^a   Smith, B R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; COMPLEMENT; COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; LEUKOCYTE ELASTASE; MONOCLONAL ANTIBODY; PADGEM PROTEIN; TRYPSIN INHIBITOR;

ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACORPOREAL CIRCULATION; HUMAN; HUMAN CELL; LEUKOCYTE; LEUKOCYTE ACTIVATION; MONOCYTE; PRIORITY JOURNAL; SIMULATION; THROMBOCYTE; THROMBOCYTE ACTIVATION;

EID: 0032886375     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(99)70183-2     Document Type: Article

References (28)

1. D Parker J Cantrell R Karp R Stroud S Digerness Changes in serum complement and immunoglobulins following cardiopulmonary bypass Surgery 71 1972 824 827
2. J Steinberg D Kapelanski J Olson J Weiler Cytokine and complement levels in patients undergoing cardiopulmonary bypass J Thorac Cardiovasc Surg 106 1993 1008 1016
3. L Williams W Burke R Steele Complement: function and clinical relevance Ann Allergy 60 1988 293 300
4. T Wiedmer CT Esmon PJ Sims Complement proteins C5b-9 stimulate procoagulant activity through the platelet prothrombinase Blood 68 1986 875 880
5. T Wiedmer CT Esmon PJ Sims On the mechanism by which complement proteins C5b-9 increase platelet prothrombinase activity J Biol Chem 261 1986 14587 14592
6. T Wiedmer P Sims Participation of protein kinases in complement C5b-9 induced shedding of platelet plasma membrane vesicles Blood 78 1991 2880 2886
7. SA Hamburger RP McEver GMP-140 mediates adhesion of stimulated platelet to neutrophils Blood 75 1990 550 555
8. C Rinder J Bonnert H Rinder J Mitchell K Ault R Hillman Platelet activation and aggregation during cardiopulmonary bypass Anesthesiology 74 1991 388 393
9. C Rinder D Gaal L Student BR Smith Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass J Thorac Cardiovasc Surg 107 1994 280 288
10. C Rinder J Bonan H Rinder J Mathew R Hines BR Smith Cardiopulmonary bypass induces leukocyte-platelet adhesion Blood 79 1992 1201 1205
11. M Tonnesen D Anderson T Springer A Knedler N Avdi P Henson Adherence on neutrophils to cultured human microvascular endothelial cells: simulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family J Clin Invest 83 1989 6337 6346
12. R Hattori KK Hamilton RD Fugate RP McEver PJ Sims Complement proteins C5b-9 induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface J Biol Chem 264 1989 9053 9060
13. 1 J Lab Clin Med 105 1985 601 607
14. J Kappelmayer A Bernabie LH Edmunds Jr T Edgington RW Colman Tissue factor is expressed on monocytes during simulated extracorporeal circulation Circ Res 72 1993 1075 1081
15. CS Rinder HM Rinder BR Smith Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation J Clin Invest 96 1995 1564 1572
16. SE Rollins LA Matis JP Springhorn Monoclonal antibodies directed against human C5 and C8 block complement-mediated damage of xenogeneic cells and organs Transplantation 60 1995 1284 1292
17. HM Rinder J Bonan CS Rinder KA Ault BR Smith Activated and unactivated platelet adhesion to monocytes and neutrophils Blood 78 1991 1760 1769
18. HM Rinder J Bonan CS Rinder KA Ault BR Smith Dynamics of leukocyte-platelet adhesion in whole blood Blood 78 1991 173 176
19. E Leo C Gemmell Minimal P-selectin content required for platelet-leukocyte adhesion Blood 82 Suppl 1 1993 621a
20. PJ Sims T Wiedmer Induction of cellular procoagulant activity by the membrane attack complex of complement Semin Cell Biol 6 1995 275 282
21. J Boldt C Osmer LC Linke G Gorlach G Hempelmann Hypothermic versus normothermic cardiopulmonary bypass: influence on circulation adhesion molecules J Cardiothorac Vasc Anesth 10 1996 342 347
22. J Kappelmayer A Bernabei N Gikakis LH Edmunds Jr RW Colman Upregulation of Mac-1 surface expression on neutrophils during SECC J Lab Clin Med 121 1993 118 126
23. BP Morgan Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects Biochem J 1989 2614 2641
24. AK Campbell BP Morgan Monoclonal antibodies demonstrate protection of polymorphonuclear leukocytes against complement attack Nature 317 1985 164 166
25. VP Addonizio EJ Macarak S Niewiarowski RW Colman LH Edmunds Jr Preservation of human platelets with prostaglandin E1 during in vitro simulation of cardiopulmonary bypass Circ Res 44 1979 350 357
26. T Palabrica R Lobb BC Furie Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets Nature 359 1992 848 851
27. J Musial S Niewiarowski D Hershock Loss of fibrinogen receptors from the platelet surface during simulated extracorporeal circulation J Lab Clin Med 105 1985 514 522
28. A Amirhovsravi M Alexander K May The importance of platelets in the expression of monocyte tissue factor antigen measured by a new whole blood flow cytometric assay Thromb Haemost 75 1996 87 95