Transport of fluid and solutes in the body. II. Model validation and implications

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 3 46-3, 1999, Pages

  Gyenge, C C ^a   Bowen, B D ^a   Reed, R K ^b   Bert, J L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Cell volume; Hyperosmolarity; Interstitial volume; Plasma osmolarity; Plasma volume expansion

Indexed keywords

ION; PROTEIN;

ARTICLE; CAPILLARY WALL; CELL VOLUME; FLUID TRANSPORT; HYPEROSMOLARITY; ION TRANSPORT; MATHEMATICAL MODEL; PLASMA OSMOLARITY; PLASMA VOLUME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

EID: 0032885716     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.3.h1228     Document Type: Article

References (15)

1. Carlson, D. E., M. D. Kligman, and D. S. Gann. Impairment of blood volume restitution after large hemorrhage: a mathematical model. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R1163-R1177, 1996.
2. Cervera, A. L., and G. Moss. Crystalloid distribution following hemorrhage and hemodilution: mathematical model and prediction of optimum volumes for equilibration at normovolemia. J. Trauma 14: 506-520, 1974.
3. Chapple, C., B. D. Bowen, R. K. Reed, S. L. Xie, and J. L. Bert. A model of human microvascular exchange: parameter estimation based on normal and nephrotics. Comput. Methods Programs Biomed. 41: 33-54, 1993.
4. Curry, F. E. Permeability coefficients of the capillary wall to low molecular weight hydrophilic solutes measured in single perfused capillaries of frog mesentery. Microvasc. Res. 17: 290-308, 1979.
5. Kleinman, L. I., and J. M. Lorenz. Physiology and pathophysiology of body water and electrolytes. In: Clinical Chemistry: Theory, Analysis and Correlation, edited by L. A. Kaplan and A. J. Pesce. St. Louis, MO: Mosby, 1984, p. 366-370.
6. Gyenge, C. C., B. D. Bowen, R. K. Reed, and J. L. Bert. Transport of fluid and solutes in the body. I. Formulation of a mathematical model. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1215-H1227, 1999.
7. Manning, R. H., and A. C. Guyton. Dynamics of fluid distribution between the blood and interstitium during overhydration. Am. J. Physiol. 238 (Heart Circ. Physiol. 7): H645-H651, 1980.
8. Mazzoni, M. C., P. Borgstrom, K.-E. Arfors, and M. Intaglietta. Dynamic fluid redistribution in hyperosmotic resuscitation of hypovolemic hemorrhage. Am. J. Physiol. 255 (Heart Circ. Physiol. 24): H629-H637, 1988.
9. Onarheim, H. Fluid shifts following 7% hypertonic saline (2400 mosmol/L) infusion. Shock 3: 350-354, 1995.
10. Onarheim, H., T. Lund, and R. K. Reed. Thermal injury. I. Acute hemodynamic effects of fluid resuscitation with lactated Ringer's, plasma, and hypertonic saline (2400 mosmol/l) in the rat. Circ. Shock 27: 13-24, 1989.
11. Onarheim, H., A. E. Missavage, G. C. Kramer, and R. A. Gunther. Effectiveness of hypertonic saline-dextran 70 for initial fluid resuscitation of major burns. J. Trauma 30: 597-603, 1990.
12. Reed, R. K., B. D. Bowen, and J. L. Bert. Microvascular exchange and interstitial volume regulation in the rat: implications of the model. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H2081-H2091, 1989.
13. Wolf, M. B. Estimation of whole-body capillary transport parameters from osmotic transient data. Am. J. Physiol. 242 (Regulatory Integrative Comp. Physiol. 11): R227-R236, 1982.
14. Xie, S. L., R. K. Reed, B. D. Bowen, and J. L. Bert. A model of human microvascular exchange. Microvasc. Res. 49: 141-162, 1995.
15. Yudilevich, D. L., E. M. Renkin, O. A. Alvarez, and I. Bravo. Fractional extraction and transcapillary exchange during continuous and instantaneous tracer administration. Circ. Res. 23: 325-336, 1968.