Modelling cortical cataractogenesis 21: In diabetic rat lenses taurine supplementation partially reduces damage resulting from osmotic compensation leading to osmolyte loss and antioxidant depletion

Experimental Eye Research

Volumn 69, Issue 3, 1999, Pages 279-289

  Mitton, K P ^a   Linklater, H A ^a   Dzialoszynski, T ^a   Sanford, S E ^b   Starkey, K ^a   Trevithick, J R ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

Amino acids; Antioxidant loss; Chemiluminescence; Model diabetic cataract; Osmotic compensation; Peroxide; Streptozotocin; Superoxide; Taurine

Indexed keywords

PEROXIDE; STREPTOZOCIN; SUPEROXIDE; TAURINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CATARACT; CATARACTOGENESIS; CHEMOLUMINESCENCE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; LENS; NONHUMAN; OSMOREGULATION; OSMOTIC STRESS; PRIORITY JOURNAL; RAT;

EID: 0032885184     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1999.0696     Document Type: Article

References (69)

1. Al-Ghoul K. J., Novak L. A., Kuzak J. R. The structure of posterior subcapsular cataracts in the Royal College of Surgeons (RCS) rats. Exp. Eye Res. 67:1998;163-178.
2. Babior B. M., Crowley C. A. Chronic granulomatous disease and other discorders of oxidative killing by phagocytes. Stanbury et al. The metabolic basis of inherited disease. 1983;1956-1985 McGraw Hill.
3. Beyer-Mears A., Diecke F. P., Mistry K., Ellison C., Cruz E. Effect of pyruvate on lens myo-inositol transport and polyol formation in diabetic cataract. Pharmacology. 55:1997;78-86.
4. Bhuyan K. C., Bhuyan D. K. Molecular mechanism of cataractogenesis III: Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract. Curr. Eye Res. 3:1984;67-82.
5. Crabbe, M. J. C. and Wolff, S. R. (1984). Monosaccharide autoxidation - A novel factor in diabetic cataractogenesis? Abstracts, Sixth International Congress of Eye Research, p. 117.
6. Crabbe, M. J. C. and Goode, D. J. (1998) Aldose reductase: a window to the treatment of diabetic complications. Prog. Retinal Eye Res. 17: 313-383.
7. Creighton M. O., Trevithick J. R. Cortical cataract formation prevented by vitamin E and glutathione. Exp. Eye Res. 29:1979;689-693.
8. Creighton M. O., Trevithick J. R., Mousa G. Y., Percy D. H., McKinna A. J., Dyson C., Maisel H., Bradley R. Globular bodies: A primary cause of the opacity in senile and diabetic posterior cortical subcapsular cataracts? Can. J. Ophthalmol. 13:1978;166-181.
9. Creighton M. O., Stewart-DeHaan P. J., Ross W. M., Sanwal M., Trevithick J. R. Modelling cortical cataractogenesis. I. In vitro effects of glucose, sorbitol and fructose on intact rat lenses in medium 199. Can. J. Ophthalmol. 15:1980;183-188.
10. Delamere N. A., Manning R. E., Jr., Liu L., Moseley A. E., Dean W. L. Na,K-ATPase polypeptide upregulation responses in lens epithelium. Invest. Ophthalmol. Vis. Sci. 39:1998;763-768.
11. Delamere N. A. Ascorbic acid and the eye. Subcell Biochem. 25:1996;313-329.
12. Diecke F. P., Beyer-Mears A. A mechanism for regulatory volume decrease in cultured lens epithelial cells. Curr. Eye Res. 16:1997;279-288.
13. Fedorenko, B. S., Kabacenko, A. N., Jarcev, E. I., Kolesnikov, J. A. and Vajnstejn, E. S. (1978). [Effect of taurine on the dynamics of development of experimental cataracts in animals]. [German title, Der Einfluss von Taurin auf die Dynamik der Entwicklung experimenteller Katarakte bei Tieren.] Radiobiol Radiother (Berl). 19, 452-8.
14. Ganapathy V., Ramamoorthy J. D., Del Monte M. A., Liebach F. H., Ramamoorthy S. Cyclic AMP-dependent up-regulation of the taurine transporter in a human retinal epithelial cell line. Curr. Eye Res. 14:1995;843-850.
15. +-ATPase. Proc. Natl. Acad. Sci. USA. 80:1983;2044-2048.
16. Gupta K., Mathur R. L. Studies on synthesis and uptake of taurine in rat lens in vitro. Exp. Eye Res. 37:1983a;385-391.
17. Gupta K., Mathur R. L. Distribution of taurine in the crystalline lens of vertebrate species and in cataractogenesis. Exp. Eye Res. 37:1983b;379-384.
18. Gupta K., Mathur R. L., Agarwal L. P. Taurine in ocular tissues of vertebrate species. Exp. Eye Res. 32:1981;793-796.
19. Hayes K. C., Pronczuk A., Addessa A. E., Stephan Z. F. Taurine modulates platelet aggregation in cats and humans. Am. J. Clin. Nutr. 49:1989;1211-1216.
20. Hightower K. R., Riley M. V., McCready J. Regional distribution of calcium in alloxan diabetic rabbit lens. Curr. Eye Res. 8:1989;517-521.
21. Jernigan H. M., Laranag. Effects of riboflavin-sensitized photo-oxidation on choline metabolism in cultured rat lens. Curr. Eye Res. 3:1984;121-126.
22. Kanwar, R. and Balasubramanian, D. (1998). Dityrosine-linked dimer of γB-crystallin. Abstracts Second Asian Cataract Research Conference, Pusan, Korea, pp31.
23. Kilic F., Mitton K., Dzialoszynski T., Sanford S. E., Trevithick J. R. Modelling cortical cataractogenesis 14: Reduction in lens damage in diabetic rats by a dietary regimen combining vitamins C and E and beta-carotene. Dev. Ophthalmol. 26:1994;63-72.
24. Kilic F, Bhardwaj R, Caulfeild J., Trevithick J. R. Modelling Cortical Cataractogenesis 22: Is In vitro Reduction of Damage in Model Diabetic Rat Cataract by Taurine Due to Its Antioxidant Activity? Exp. Eye Res. 69:1999;291-300.
25. Kilic F., Trevithick J. R. Modelling cortical cataractogenesis XXIX. Calpain proteolysis of lens fodrin in cataract. Biochem. Molec. Biol. Internat. 45:1998;963-978.
26. Kinoshita J. H., Merola L. O., Dikmak E. Osmotic changes in experimental galactose cataracts. Exp. Eye Res. 1:1962;405-410.
27. Kinoshita J. H., Barber G. W., Merola L. O., Tung B. Changes in the levels of free amino acids and myo-inositol in the galactose-exposed lens. Invest. Ophthalmol. 8:1969;625-632.
28. Kuck J. F. R. Metabolism of the lens. Bellows J. G. Cataract and abnormalities of the lens. 1975;97-123 Grune and Stratton, New York.
29. Lake N. Taurine and GABA in the rat retina during postnatal development. Vis. Neurosci. 11:1994a;253-260.
30. Lake N. Alterations of ventricular contractility and myofibril loss in taurine-deficient hearts. Adv. Exp. Med. Biol. 359:1994b;335-342.
31. Lee A. Y., Chung S. S., Chung S. K. Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens. Proc. Nat. Acad. Sci. USA. 92:1995;2780-2784.
32. Linklater H. A., Galsworthy P., Stewart-DeHaan P. J. The use of guanidinium chloride in the preparation of stable cellular homogenates containing ATP. Anal. Biochem. 148:1984;44-49.
33. Linklater H. A., Dzialoszynski T., McLeod H. L., Sanford S. E., Trevithick J. R. Modelling cortical cataractogenesis VIII. Effects of butylated hydroxytoluene (BHT) in protein leakage from lenses in diabetic rats. Exp. Eye Res. 43:1986;305-313.
34. Linklater H. A., Dzialoszynski T., McLeod H. L., Sanford S. E., Trevithick J. R. Modelling cortical cataractogenesis XI. Vitamin C reduces γ-crystallin leakage from lenses in diabetic rats. Exp. Eye Res. 51:1990;241-247.
35. Linklater H. A., Dzialoszynski T., McLeod H. L., Sanford S. E., Trevithick J. R. Modelling cortical cataractogenesis XII. Supplemental Vitamin A treatment reduces γ-crystallin leakage from lenses in diabetic rats. Lens Eye Tox. Res. 9:1992;115-126.
36. Malone J. I., Lowitt S., Cook W. R. Nonosmotic diabetic cataracts. Pediatric Res. 27:1990;293-296.
37. Mitton K. P., Dean P. A. W., Dzialoszynski T., Xiong H., Sanford S. E., Trevithick J. R. 'Modelling cortical cataractogenesis 13. Early effects of lens ATP/ADP and glutathione in the streptozotocin rat model of the diabetic cataract'. Exp. Eye Res. 56:1993;187-198.
38. Mitton, K. P., Dzialoszynski, T., Sanford, S. E. and Trevithick, J. R. (1994). Multiple antioxidant deficit in precataractous streptozotocin diabetic rat lens: a result of osmotic compensation. Invest. Ophthalmol. Vis. Sci. 35, 1570 (par. 1465).
39. Mitton K. P., Hess J. L., Bunce G. E. Causes of decreased phase transition temperature in selenite cataract model. Invest. Ophthalmol. Vis. Sci. 36:1995;914-924.
40. Mitton K. P., Hess J. L., Bunce G. E. Free amino acids reflect impact of selenite-dependent stress on primary metabolism in rat lens. Curr. Eye Res. 16:1997;997-1005.
41. Mitton K. P., Dzialoszynski T., Sanford S. E., Trevithick J. R. Cysteine and ascorbate loss in the diabetic rat lens prior to hydration changes. Curr. Eye Res. 16:1997;564-571.
42. Miyamoto Y., Marczin N., Catravas J. D., Del Monte M. A. Cholera toxin enhances taurine uptake in cultures of human retinal pigment epithelial cells. Curr. Eye Res. 15:1996;229-236.
43. Mollerup J., Lambert I. H. Phosphorylation is involved in the regulation of the taurine influx via the beta-system in Ehrlich ascites tumor cells. J. Membrane Biol. 150:1996;73-82.
44. Norusis, M. J./SPSS Inc. (1988) SPSS/PC+ V2.0 Base Manual. SPSS Inc., Chicago, IL.
45. O'Keefe T. L., Hess H. H., Zigler J. S., Kuwabara T., Knapka J. J. Prevention of cataracts in pink-eyed RCS rats by dark rearing. Exp. Eye Res. 51:1990;509-517.
46. Petchey M., Crabbe M. J. C. Analysis of carbohydrates in lens erythrocytes and plasma by high performance liquid chromatography of nitrobenzoate derivatives. J. Chromatog. 307:1984;180-184.
47. Philipson B. Distribution of protein within the normal rat lens. Invest. Ophthalmol. 8:1969a;271-280.
48. Philipson B. Galactose cataract: Changes in protein distribution during development. Invest. Ophthalmol. 8:1969b;281-289.
49. Ramamoorthy S., Del Monte M. A., Liebach F. H., Ganapathy V. Molecular identity and calmodulin regulation of the taurine transporter in a human retinal pigment epithelial cell line. Curr. Eye Res. 13:1994;523-529.
50. Reddy D. V. N. Amino acid transport in the lens in relation to sugar cataracts. Invest. Ophthalmol. 4:1965;700-708.
51. Riley M. V., Schwartz C. A., Peters M. I. Interactions of ascorbate and H2O2: implications for in vitro studies of lens and cornea. Curr. Eye Res. 5:1986;207-216.
52. Ross W. M., Creighton M. O., Stewart-DeHaan P. J., Sanwal M., Hirst M., Trevithick J. R. Modelling cortical cataractogenesis III. In vivo effects of vitamin E on cataractogenesis in diabetic rats. Can. J. Ophthalmol. 17:1982;61-66.
53. Ross W. M., Creighton M. O., Inch W. R., Trevithick J. R. Radiation cataract formation diminished by vitamin E in rat lenses in vitro. Exp. Eye Res. 36:1983a;645-653.
54. Ross W. M., Creighton M. O., Trevithick J. R., Stewart-DeHaan P. J., Sanwal M. Modelling cortical cataractogenesis VI. Induction by glucose in vitro or in diabetic rats: Prevention and reversal by glutathione. Exp. Eye Res. 37:1983b;559-573.
55. Taylor A. Associations between nutrition and cataract. Nutrition Reviews. 47:1989;225-234.
56. Tchoumkeu-Nzouessa G. C., Rebel G. Activation of protein kinase C down-regulates glial but not neuronal taurine uptake. Neurosci. Lett. 206:1996;61-64.
57. Thornalley P., Wolff S., Crabbe J., Stern A. The autoxidation of glyceraldehyde and other simple monosaccharides under physiological conditions catalysed by buffer ions. Biochim. Biophys. Acta. 797:1984;276-287.
58. Trevithick J. R., Dzialoszynski T. A new technique for enhancing luminol luminescent detection of free radicals and reactive oxygen species. Biochem. Molec. Biol. Internat. 33:1994;1179-1190.
59. Trevithick J. R., Dzialoszynski T. Endogenous superoxide-like species and antioxidant activity detected by luminol luminescence. Biochem. Molec. Biol. Internat. 41:1997;695-705.
60. Trevithick J. R., Creighton M. O., Ross W. M., Stewart-DeHaan P. J., Sanwal M. Modelling cortical cataractogenssis. 2. In vitro effects on the lens of agents preventing glucose- and sorbitol-induced cataract. Can. J. Ophthalmol. 16:1981;32-38.
61. Trevithick J. R., Linklater H. A., Mitton K. P., Dzialoszynski T., Sanford S. E. Modelling cortical cataractogenesis: IX. Activity of vitamin E and esters in preventing cataracts and γ-crystallin leakage from lenses in diabetic rats. In Vitamin E: Biochemistry and Health Implications. Annals NY Acad. Sci. 570:1989;358-371.
62. Trevithick J. R., Bantseev V., Dzialoszynski T. Mitochondrial changes in rat lens glucose-induced diabetic cataractogenesis in vitro: vitamin E and Lipoate protect. (Association for Research in Vision and Ophthalmology April 1997). Invest. Ophthalmol. Visual Sci. 38:1997;S1171 (No. 5451).
63. Varma S. D., Kinoshita J. H. Sorbitol pathway in diabetic and galactosemic rat lens. Biochim. Biophys. Acta. 338:1974;632-640.
64. Varma S. D., Ets T. K., Richards R. D. Protection against superoxide radicals in rat lens. Ophthalmic Res. 9:1977;421-431.
65. Varma S. D., Chand D., Sharma Y. R., Kuck J. F., Richards R. D. Oxidative stress on lens and cataract formation: Role of light and oxygen. Curr. Eye Res. 3:1984;35-58.
66. Vodovozov, A. M. and Glotova, N. M. (1981). [Results of taurine therapy in senile cataracts]. [Russian, Original Title: Rezul'taty lecheniia starcheskikh katarakt taurinom.] Vestn Oftalmol. (2):44-5.
67. Wolff S. P., Dean R. T. Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem. J. 245:1987;243-250.
68. Wright C. E., Lin T. T., Lin Y. Y., Sturman J. A., Gaull G. E. Taurine scavenges oxidized chlorine in biological systems. Prog. Clin. Biol. Res. 179:1985;137-147.
69. Zigler J. S., Goosey J. D. Singlet oxygen as a possible factor in human senile nuclear cataract development. Curr. Eye Res. 3:1984;59-66.