Influences of surgical castration on the thymus of male rats

Journal of Reproductive Immunology

Volumn 44, Issue 1-2, 1999, Pages 29-39

  Windmill, K F ^a   Lee, V W K ^a  

^a DEAKIN UNIVERSITY   (Australia)

Author keywords

Castration; MTT; Thymosins; Thymus

Indexed keywords

CONCANAVALIN A; POLYCLONAL ANTIBODY; THYMOSIN; THYMOSIN ALPHA1; THYMOSIN BETA4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASTRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HORMONE DETERMINATION; IMMUNE FUNCTION TEST; IMMUNOASSAY; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; THYMUS;

ANIMALS; CATTLE; CONCANAVALIN A; LYMPHOCYTES; MALE; MITOGENS; ORCHIECTOMY; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TESTIS; THYMOSIN; THYMUS GLAND;

EID: 0032884769     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(99)00006-6     Document Type: Article

References (24)

1. Aboussaouira, T., Marie, C., Brugal, G., Idelman, S., 1991. Inhibitory effect of 17β-estradiol on thymocyte proliferation and metabolic activity in young rats. Thymus 17, 167-180.
2. Ataya, K.M., Sakr, W., Blacker, C.M., Mutchnick, M.G., Latif, Z.A., 1989. Effects of GnRH agonists on the thymus in female rats. Acta Endocrinol. 121, 833-840.
3. Comsa, J., Leonhardt, H., Ozminski, K., 1979. Hormonal influences on the secretion of the thymus. Thymus l, 81-93.
4. Fitzpatrick, F.T.A., Greenstein, B.D., 1987. Effects of various steroids on the thymus, spleen, ventral prostate and seminal vesicles in old orchidectomized rats. J. Endocrinol. 113, 51-55.
5. Ford, J.J., Vakharia, D.D., Anderson, L.L., Klindt, J., 1990. Thymosin-β4 concentrations during the estrous cycle and after hypophyseal stalk transection of female pigs. Proc. Soc. Exp. Biol. Med. 193, 185-189.
6. Goldstein, A.L., Low, T.L.K., Thurman, G.B., Zatz, M.M., Hall, N., Chen, J., Hu, S., Naylor, P.B., McClure, J.E., 1981. Current status of thymosin and other hormones of the thymus gland. Rec. Prog. Horm. Res. 37, 369-412.
7. Greenstein, B.D., Fitzpatrick, F.T.A., Adcock, I.M., Kendall, M.D., Wheeler, M.J., 1986. Reappearance of the thymus in old rats after orchidectomy: inhibition of regeneration by testosterone. J. Endocrinol. 110, 417-422.
8. Grossman, C.J., 1985. Interactions between the gonadal steroids and the immune system. Science 227, 257-261.
9. Grossman, C.J., Nathan, P., Taylor, B.B., Sholiton, L.J., 1979a. Rat thymic dihydrotestosterone receptor: preparation, location and physicochemical properties. Steroids 34, 539-553.
10. Grossman, C.J., Sholiton, L.J., Nathan, P., 1979b. Rat thymic estrogen receptor-I. Preparation, location and physicochemical properties. J. Steroid Biochem. 11, 1233-1240.
11. Grossman, C.J., Sholiton, L.J., Roselle, G.A., 1982. Estradiol regulation of thymic lymphocyte function in the rat: mediation by serum thymic factors. J. Steroid Biochem. 16, 683-690.
12. Grossman, C.J., Sholiton, L.J., Roselle, G.A., 1983. Dihydrotestosterone regulation of thymocyte function in the rat: mediation by serum factors. J. Steroid Biochem. 19, 1459-1467.
13. Hu, S.K., Badamchian, M., Mitcho, Y.L., Goldstein, A.L., 1989. Thymosin enhances the production of IL-1 α by human peripheral blood monocytes. Lymphokine Res. 8, 203-214.
14. Huang, K.Y., Kind, P.D., Jagoda, E.M., Goldstein, A.L., 1981. Thymosin treatment modulates production of Interferon. J. Interferon Res. 1, 411-420.
15. Lee, V.W.K., Meade, B.J., 1987. Prepubertal gonadectomy increases growth of thymus glands in rats. Med. Sei. Res. 15, 1367.
16. Low, T.L.K., Thurman, G.B., McAdoo, M., McClure, J., Rossio, J.L., Naylor, P.H., Goldstein, A.L., 1979. The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin al and polypeptide β1 from calf thymus. J. Biol. Chem. 254, 981-986.
17. Marchetti, B., Guarcello, V., Morlae, M.C., Bartoloni, G., Farinella, Z., Cordaro, S., Scapagnini, U., 1989. Endocrinology 125, 1037-1045.
18. Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
19. Rouabhia, M., Ghanmi, Z., Chakir, J., Othmane, O., Deschaux, P., 1990. Effect of luteotrophic hormone (LH) and thymosin on mitogen-induced blast transformation of Balb/c mouse lymphoid cells. Life Sei. 46, 257-264.
20. Sabharwal, P., Varma, S., Malarkey, W.B., 1992. Human thymocytes secrete luteinizing hormone: an autocrine regulator of T-cell proliferation. Biochem. Biophys. Res. Commun. 187, 1187-1192.
21. Sztein, M.B., Serrate, S.A., Goldstein, A.L., 1986. Modulation of interleukin 2 receptor expression on normal human lymphocytes by thymic hormones. Proc. Natl. Acad. Sei. USA 83, 6107-6111.
22. Windmill, K.F., Lee, V.W.K., 1998. Effects of castration on the lymphocytes of the thymus, spleen and lymph nodes. Tissue Cell 30, 104-111.
23. Windmill, K.F., Meade, B.J., Lee, V.W.K., 1993. Effect of prepubertal gonadectomy and sex steroid treatment on the growth and lymphocyte populations of the rat thymus. Reprod. Fertil. Dev. 5, 73-81.
24. Zatz, M.M., Goldstein, A.L., 1985. Thymosins, lymphokines and the immunology of aging. Gerontology 31, 263-277.