Regulation of effector cell functions through the ligation of lymphocyte function-associated antigen-1 and intracellular adhesion molecule-1 leads to spontaneous regression of a rat histiocytoma

Scandinavian Journal of Immunology

Volumn 50, Issue 4, 1999, Pages 378-386

  Jyothi, M Divya ^a   Varalakshmi, Ch ^a   Khar, A ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; APOPTOSIS; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL INTERACTION; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; EFFECTOR CELL; FLOW CYTOMETRY; HISTIOCYTOMA; IMMUNE RESPONSE; LYMPHOCYTE FUNCTION; LYMPHOKINE ACTIVATED KILLER CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REGRESSION ANALYSIS; REMISSION; TARGET CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; APOPTOSIS; CELL ADHESION; CYTOTOXICITY, IMMUNOLOGIC; HISTIOCYTOMA, BENIGN FIBROUS; IMMUNOTHERAPY; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKINS; KILLER CELLS, NATURAL; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; RATS; RATS, WISTAR; RECEPTOR CROSS-TALK; REMISSION INDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032884402     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1999.00608.x     Document Type: Article

References (37)

1. Rothlein R, Springer TA. The requirement for lymphocyte function-associated antigen I in homotypic leucocyte adhesion stimulated by phorbol ester, J Exp Med 1986;163:1132-49.
2. Simmons D, Makgoba MW, Seed B. ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature 1988;331:624-7.
3. Staunton DE, Marlin SD, Stratowa C, Dustin ML, Springer TA. Primary structure of ICAM-1 demonstrates interaction between members of immunoglobulin and integrin supergene families. Cell 1988;52:925-33.
4. Dustin ML, Springer TA. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 1989;341:619-24.
5. Smith CW, Rothlein R, Hughes BJ et al. Recognition of an endothelial determinant for CD18-dependent human neutrophil adherence and transendothelial migration. J Clin Invest 1988;82:1746-56.
6. Marlin SD, Springer TA. Purified intracellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell 1987;51:813-9.
7. Smith CW, Marlin SD, Rothlein R, Toman C, Anderson DC. Cooperative interactions of LFA-1 and Mac-1 with intercellular and transendothelial migration of human neutrophils in vitro. J Clin Invest 1989;83;2008-17.
8. Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL-1 and interferon-gamma: tissue distribution, biochemistry, and function of natural adherence molecule (ICAM-1). J Immunol 1986;137:245-54.
9. Rothlein R, Dustin ML, Marlin SD, Springer TA. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J Immunol 1986;137:1270-4.
10. Takei F. Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2). J Immunol 1985;134:1403-7.
11. Lub M, Van Kooyk Y, Figdor CG. Ins and outs of LFA-1. Immunol Today 1995;16:479-83.
12. Koopman G, Keehnen RM, Lindhout E, Newman W, Shiwizu Y, van-Seventer GA. Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (Cd49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. J Immunol 1994;152:3760-7.
13. Figdor CG, Van Kooyk Y, Keizer GD. On the mode of action of LFA-1. Immunol Today 1990;11:277-80.
14. Moy VT, Brian AA. Signalling by lymphocyte function-associated antigen-1 (LFA-1) in B cells: enhanced antigen presentation after stimulation through LFA-1. J Exp Med 1992;175:1-7.
15. Harning R, Pelletier J, Lubbe K, Takei F, Merluzzi VJ. Reduction in the severity of graft-versus-host disease and increased survival in allogenic mice by treatment with monoclonal antibodies to cell adhesion antigens LFA-1 alpha and MALA-2. Transplantation 1991;52:842-5.
16. Chong AS-F, Boussy IA, Jiang X et al. CD54/ICAM-1 is a costimulator of NK cell-mediated cytotoxicity. Cell Immunol 1994;157:92-105.
17. Khar A. Development and characterization of a rat histiocyte-macrophage tumor cell line. J Natl Cancer Inst 1986;76:871-8.
18. Kausalya S, Hegde SP, Bright JJ, Khar A. Mechanism of antibody-dependent natural killer cell-mediated AK-5 tumor cell death. Exp Cell Res 1994;212:285-90.
19. Hegde SP, Bright JJ, Kausalya S, Khar A. AK-5 tumor induced expression of IL-12: role of IL-12 in AK-5 regression. Cell Immunol 1995;162:241-7.
20. Kausalya S, Varalakshmi Ch, Khar A. Correlation of in vitro and in vivo effects of interferon-γ with the spontaneous regression of a rat histiocytoma. J Interferon Cytokine Res 1995;15:647-54.
21. Khar A, Leela Kumari A, Ali AM. Characterization of spontaneous immunolgoical regression in histiocytoma: II. Participation of tumor necrosis factor. Int J Oncol 1993;2:399-402.
22. Rao KL, Varalakshmi C, Kuman AL, Khar A. Interaction between B.7 and CD28 costimulatory molecules is essential for the activation of effector function mediating spontaneous tumour regression. Scand J Immunol 1999;49:633-40.
23. Khar A, Ali AM. Adaptation of rat histiocytoma cells AK-5, to growth in culture. In vitro Cell Dev Biol 1990;26:1024-5.
24. Khar A, Pardhasaradhi BVV, Varalakshmi Ch, Mubarak A, Kumari AL. Natural killer cell as the effector which mediates in vivo apoptosis in AK-5 tumor cells. Cell Immunol 1997;177:86-92.
25. Khar A, Kausalya S, Kamal MA. AK-5 tumor-induced modulation of host immune function: upregulation of Th-1 type cytokine response mediates early tumor regression. Cytokine Mol Ther 1996;2:31-46.
26. Bowtell DD. Rapid isolation of eukaryotic DNA. Anal Biochem 1987;162:463-5.
27. Ijsselmuiden OE, Herbrink P, Meddens MJM, Tank B, Stole E, Van Eijk RVW. Optimizing the solid-phase immunofiltration assay: a rapid alternative to immunoassays. J Immunol Methods 1989;119:35-43.
28. Khar A, Varalakshmi Ch, Pardhasaradhi BVV, Ali AM. Generation of cytotoxic monoclonals against AK-5 histiocytoma: conjugation with daunomycin and use in chemotherapy, Cancer Lett 1992;64:163-9.
29. Rosato A, Mandruzzato S, Bronte V et al. Role of anti-LFA-1 and anti-ICAM-1 combined MAb treatment in the rejection of tumors induced by Moloney murine sarcoma virus (M-MSV). Int J Cancer 1995;61:355-62.
30. Wang J, Lenardo MJ. Essential lymphocyte function associated-1 (LFA-1): intercellular adhesion molecule interactions for T cell-mediated B cell apoptosis by Fas-APO-1/CD95. J Exp Med 1997:186:1171-6.
31. Nagler A, Lanier LL, Phillips JH. Constitutive expression of high affinity interleukin-2 receptors on human CD16-natural killer cells in vivo. J Exp Med 1990;171:1527-33.
32. Muralikrishna K, Varalakshmi Ch, Khar A. Differential modulation of LAK and ADCC functions of natural killer cells from AK-5 tumor-bearing rats by IL-2, IL-12 and IFN-γ. Cytokines Cell Mol Therapy 1997;3:51-8.
33. Binnerts ME, van Kooyk Y, Simmons DL, Figdor CG. Distinct binding of T lymphocytes to ICAM-1, -2 or -3 upon activation of LFA-1. Eur J Immunol 1994;24:2155-60.
34. + T lymphocytes. J Immunol 1992;148:1985-92.
35. Springer TA. Adhesion receptors of the immune system. Nature 1990;346:425-33.
36. Poudrier J, Owens T. Th1 and Th2 help for B cells: differential capacity for induction of autonomous responsiveness to IL-2. Int Immunol 1995;7:1021-7.
37. Owens T. A role for adhesion molecules in contact-dependent T help for B cells. Eur J Immunol 1991;21:979-83.