Trisomy 12 in Juvenile granulosa cell tumor of the ovary during pregnancy: A report of two cases

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 44, Issue 9, 1999, Pages 826-832

  Tanyi, János ^a,c   Rigó Jr , János ^a   Csapó, Zsolt ^a   Szentirmay, Zoltán ^b  

^a National Institute of Oncology   (Hungary)

^b NATIONAL INSTITUTE OF ONCOLOGY   (Hungary)

^c Hungarian Natural History   (Hungary)

Author keywords

Granulosa cell tumor; Ovarian neoplasms; Pregnancy complications, neoplastic; Trisomy

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CHROMOSOME 12; CHROMOSOME ABERRATION; CONTROLLED STUDY; FEMALE; GRANULOSA CELL TUMOR; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; OVARY TUMOR; PLOIDY; PREGNANCY; PRIORITY JOURNAL; PROGNOSIS; TRISOMY; TUMOR DIAGNOSIS;

EID: 0032883960     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Ashkenazy M, Kessler I, Czernobilsky B, et al: Ovarian tumors in pregnancy. Int J Gynecol Obstet 1988;27:79-83
2. Struyk APHB, Treffers PE: Ovarian tumors in pregnancy. Acta Obstet Gynecol Scand 1984;63:421-424
3. Young RH, Dickersin GR, Scully RE: Juvenile granulosa cell tumor of the ovary: A clinicopathological analysis of 125 cases. Am J Surg Pathol 1984;8:575-596
4. Young RH, Scully RE: Sex cord-stromal, steroid cell, and other ovarian tumors with endocrine, paraendocrine, and paraneoplastic manifestations. In Blaustein's Pathology of the Female Genital Tract. Edited by RJ Kurmann. New York, Springer-Verlag, 1984, pp 783-834
5. Leveque J, Meunier B, Berger D, et al: Juvenile tumour of the ovarian granulosa during pregnancy: A case report and a review of the literature. J Gynecol Obstet Biol Reprod Paris 1994;23:283-287
6. Fletcher JA, Gibas Y, Donovan K, et al: Ovarian granulosa-stromal cell tumors are characterized by trisomy 12. Am J Pathol 1991;38:515-520
7. Speleman F, De Potter C, Dal Cin P, et al: i(12p) In a malignant ovarian tumor. Cancer Genet Cytogenet 1990;45:49-53
8. Suijkerbujik RF, Looijenga L, de-Jong B, et al: Verification of isochromosome 12p and identification of other chromosome 12 aberrations in gonadal and extragonadal human germ cell tumors by bicolor double fluorescence in situ hybridization. Cancer Genet Cytogenet 1992;63:8-16
9. Lalkin A, Lishner M, Gaber E, et al: In situ hybridization: A simple and sensitive method for detection of trisomy 12 in chronic lymphocytic leukemia. Cancer Genet Cytogenet 1993;70:21-24
10. Hopman AHN, Mooren van E, Kaa van CA, et al: Detection of numerical chromosomal aberrations using in situ hybridization in paraffin sections of routinely processed bladder cancers. Mod Pathol 1991;4:503-513
11. Serov SF, Scully RE, Sobin LH: International Histological Classification and Staging of Tumors. Geneva, World Health Organization, 1993
12. Hedley DW, Friedlander M, Taylor IW, et al: Method for analysis of cellular DNA content of paraffin embedded pathological material using flow cytometry. J Histochem Cytochem 1983;31:1333-1335
13. Powell JL, Johnson NA, Bailey CL, et al: Management of advanced juvenile granulosa cell tumor of the ovary. Gynecol Oncol 1993;48:119-123
14. Spaun E, Glavind K: Cystic juvenile granulosa cell tumor of the ovary. Acta Obstet Gynecol Scand 1988;67:177-180
15. Pejovic T, Heim S, Mandahl N, et al: Trisomy 12 is a consistent chromosomal aberration in benign ovarian tumors. Genes Chromosom Cancer 1990;2:48-52
16. Schofield ED, Fletcher JA: Trisomy 12 in pediatric granulosa-stromal cell tumors. Am J Pathol 1992;141:1265-1269
17. Person DL, Hartmann LC, Herald JF: Interphase molecular cytogenetic analysis of epithelial ovarian carcinomas. Am J Pathol 1993;142:733-741
18. Yang-Feng TL, Li SB, Leung WY, et al: Trisomy 12 and K-ras 2 amplification in human ovarian tumors. Int J Cancer 1991;48:678-681
19. Tanyi J, Tory K, Amo-Takyi B, et al: Frequent loss of chromosome 12 in human epithelial ovarian tumors: A chromosomal in situ hybridisation study. Int J Gynecol Pathol 1998;17:106-112
20. Liang JC, Kurzrock R, Gutterman JU, et al: Trisomy 12 correlates with elevated expression of p21ras in human adenosquamosus carcinoma of the lung. Cancer Genet Cytogenet 1986;23:183-188