Aberrant crypt foci in the human colon: Frequency and histologic patterns in patients with colorectal cancer or diverticular disease

American Journal of Surgical Pathology

Volumn 23, Issue 10, 1999, Pages 1256-1263

  Nascimbeni, Riccardo ^a   Villanacci, Vincenzo ^a   Mariani, Pier Paolo ^a   Di Betta, Ernesto ^a   Ghirardi, Mauro ^a   Donato, Francesco ^a   Salerni, Bruno ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Aberrant crypt foci; Colorectal cancer; Diverticular disease

Indexed keywords

ARTICLE; CANCER RISK; CELL TRANSFORMATION; COLON CARCINOGENESIS; COLON DIVERTICULOSIS; COLORECTAL CANCER; CRYPT CELL; HUMAN; HUMAN TISSUE; PRECANCER;

ADENOMA; COLON; COLORECTAL NEOPLASMS; DIVERTICULUM, COLON; FEMALE; HUMANS; HYPERPLASIA; INTESTINAL MUCOSA; MALE; PRECANCEROUS CONDITIONS;

EID: 0032883870     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199910000-00011     Document Type: Article

References (21)

1. Agresti A. Categorical data analysis. New York: John Wiley and Sons, 1992.
2. Armitage P, Berry G. Statistical methods in medical research. Oxford: Blackwell Scientific Publications, 1994.
3. Bird RP. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 1987;37:147-51.
4. Bird RP. Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 1995;93:55-71.
5. Di Gregorio C, Losi L, Fante R, Modica S, Ghidoni M, Pedroni M, Tamassia MG, Gafá L, Ponz De Leon M, Roncucci L. Histology of aberrant crypt foci in the human colon. Histopathology 1997;30: 328-34.
6. Dixon WJ, Brown MB, Engelman L, Jenrich NL. BMDP statistical software manual. Los Angeles: University of California Press, 1993.
7. Jen J, Powell SM, Papadopoulos N, Smith KJ, Hamilton SR, Vogelstein B, Kinzler KW. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-6.
8. Kostantakos AK. Siu I, Pretlow TG, Stellate TA, Pretlow TP. Human aberrant crypt foci with carcinoma in situ from a patient with sporadic colon cancer. Gastroenterology 1996;111:772-7.
9. Longacre TA, Fenoglio-Preiser CM. Mixed hyperplastic adenomatous polyps/serrated adenoma. A distinct form of colorectal neoplasia. Am J Surg Pathol 1990;14:524-37.
10. McLellan EA, Medline A, Bird RP. Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions. Cancer Res 1991;51:5270-4.
11. Morson BC, Dawsons IMP, Day DW, Jass JR, Price AB, Williams GT. Gastrointestinal pathology. Oxford: Blackwell Scientific Publications, 1990.
12. Nascimbeni R, Salerni B, Fontana MG, Mittempergher F, Ghirardi M. Aberrant crypt foci (ACF) in neoplastic and non-neoplastic human colon. Digestive Disease Week '97. May 10-16, 1997, Washington, DC: Gastroenterology 1997;112(suppl 1):A625.
13. Oohara T, Ogino A, Tohma H. Histogenesis of microscopic adenoma and hyperplastic (metaplastic) gland in nonpolyposis coli. Dis Colon Rectum 1981;24:375-84.
14. Otori K, Sugiyama K, Hasebe T, Fukushima S, Esumi H. Emergence of adenomatous aberrant crypt foci (ACF) from hyperplastic ACF with concomitant increase in cell proliferation. Cancer Res 1995;55:4743-6.
15. Pretlow TP, Barrow BJ, Ashton WS, O'Riordan MA, Pretlow TG, Jurcisek JA, Stellato TA. Aberrant crypts: putative preneoplastic foci in colonic mucosa. Cancer Res 1991;51:1564-7.
16. Pretlow TP, O'Riordan MA, Pretlow TG, Stellato TA. Aberrant crypts in human colonie mucosa: putative preneoplastic lesions. J Cell Biochem 1992;suppl 16G:55-62.
17. Pretlow TP, Roukhadze EV, O'Riordan MA, Chan JC, Amini SB, Stellato TA. Carcinoembryonic antigen in human colonic aberrant crypt foci. Gastroenterology 1994;107:1719-25.
18. Roncucci L, Medline A, Bruce WR. Classification of aberrant crypt foci and microadenomas in human colon. Cancer Epidemiol Biomarkers Prev 1991;1:57-60.
19. Roncucci L, Stamp D, Medline A, Cullen JB, Bruce WR. Identification and quantification of aberrant crypt foci and microadenomas in the human colon. Hum Pathol 1991;22:287-94.
20. Smith JS, Stern HS, Penner M, Hay K, Mitri A, Bapat BV, Gallinger S. Somatic APC and K-ras mutations in aberrant crypt foci from human colons. Cancer Res 1994;54:5527-30.
21. Yamashita N, Minamoto T, Ochiai A, Onda M, Esumi H. Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon. Gastroenterology 1995;108:434-40.