Ropivacaine: An important anesthetic agent for slow infusion and other forms of tumescent anesthesia

Dermatologic Surgery

Volumn 25, Issue 10, 1999, Pages 799-802

  Breuninger, Helmut ^a,b   Hobbach, Pierre Sebastian ^a   Schimek, Franz ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BUPIVACAINE; LIDOCAINE; PRILOCAINE; ROPIVACAINE;

ADOLESCENT; ADULT; AGED; ARTICLE; CARDIOTOXICITY; CHILD; CONTROLLED STUDY; DRUG EFFICACY; DRUG INDICATION; DRUG INFUSION; DRUG MIXTURE; DRUG POTENCY; DRUG TOLERABILITY; HUMAN; LOCAL ANESTHESIA; MAJOR CLINICAL STUDY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SKIN SURGERY; SUBCUTANEOUS DRUG ADMINISTRATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMIDES; ANESTHETICS, COMBINED; ANESTHETICS, LOCAL; CHILD; CHILD, PRESCHOOL; HUMANS; LIDOCAINE; MIDDLE AGED; PRILOCAINE;

EID: 0032883669     PISSN: 10760512     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-4725.1999.99087.x     Document Type: Article

References (21)

1. Breuninger H, Wehner-Caroli J. Slow infusion tumescent anesthesia (SITA). J Dermatol Surg 1998;24:759-63.
2. Cederholm I, Akerman B, Evers H. Local analgesic and vascular effects of intradermal ropivacaine and bupivacaine in various concentrations with and without addition of adrenaline in man. Acta Anaesthesiol Scand 1994;38:322-7.
3. Geiger P, Oldenburger K, Ventour W, Mehrkens HH. Ropivacaine 0.5 % vs 1.0% for 3-in-1 block combined with sciatic nerve block in orthopedic knee surgery. Medicom International 1998;10:218.
4. Pettersson N, Emanuelsson BM, Reventlid H, Hahn RG. High-dose ropivacaine wound infiltration for pain relief after inguinal hernia repair. A clinical and pharmacokinetic evaluation. Reg. Anesth and Pain Med 1998; 23:189-96.
5. Rosenberg PH, Kyttä J, Alila A. Absorption of bupivacaine, etidocaine, lignocaine and ropivacaine into n-heptane, rat sciatic nerve, and human extradural and subcutaneous fat. Br J Anaesth 1986;58:310-14.
6. Sztark F, Malgat M, Dabadine PH, Mazat JP. Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergerics. Anesthesiology 1998;88:1340-49.
7. Knudsen K, Beckmann-Suurküla M, Blomberg S, Edvardsson S, Edvardsson N. Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anaesth 1991;78:507-14.
8. Scott DB, Lee A, Fagan D, Bowler GMR, Bloomfield P, Lundh R. Acute toxicity of ropivacaine compared with that of bupivacaine. Anesth Analg 1989;69:563-9.
9. Feldman HS, Arthur R, Covino BG. Comparative systemic toxicity of convulsant and supraconvulsant doses of intravenous ropivacaine, bupivacaine and lidocaine in conscious dog. Anesth Analg 1989;69:794-801.
10. Pittkanen M, Feldman HS, Arthur G, Covino BG. Chronotropic and inotropic effects of ropivacaine, bupivacaine and lidocaine in the spontaneously beating and electrically paced isolated perfused rabbit heart. Reg Anesth 1992;17:183-92.
11. Reiz S, Häggmark S, Johansson G, Nath S. Cardiotoxicity of ropivacaine- an new amide local anesthetic agent. Acta Anaesthesiol Scand 1989;33:93-8.
12. Arlock P. Actions of three local anesthetics: lidocaine, bupivacaine and ropivacaine on guinea pig papillary muscle sodium channels (V max). Pharmacol Toxicol 1988;63:96-104.
13. Scutari G, Marian M, Bindoli A, et al. Mitochondrial effects of L-ropivacaine, a new local anesthetic. Biochem Pharmacol 1998;56: 1633-7.
14. Sztark F, Malgat M, Dabadine P, Mazat JP. Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergetics. Anesthesiology 1998;88:1340-9.
15. Ruetsch YA, Fattinger KE, Borgeat A. Ropivacaine-induced convulsions and severe cardiac dysrhythmia after sciatic block. Anesthesiology 1999;90:1784-6.
16. Guinard JPH, Carpenter RL, Owens BD, Nadir B. Comparison between ropivacaine and bupivacaine after subcutaneous injection in pigs: cutaneous blood flow and surgical bleeding. Reg. Anesth 1991;16:268-71.
17. Kopacz DJ, Carpenter RL, Mackey DC. Effect of ropivacaine on cutaneous capillary blood flow in pigs. Anesthesiology 1989;71: 69-74.
18. Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction: peak plasma lidocaine levels are diminished and delayed 12 hours. J Dermatol Surg Oncol 1990;16:248-63.
19. Omstead A, Kageyama N, Moy RL. Tumescent anesthesia with lidocaine dose of 55 mg/kg is safe for liposuction. J Dermatol Surg 1996;22:921-7.
20. Schimek F, Novgova L, Breuninger H. The effects and plasma levels of ropivacaine after the subcutaneous administration. Anesth Analg 1999;8(suppl);279.
21. Rao RB, Ely SF, Hoffmann RS. Deaths related to liposuction. N Engl J Med 1999;13:1471-5.