메뉴 건너뛰기




Volumn 13, Issue 5, 1999, Pages 449-454

Lack of effect of cholesterol esterase inhibitor CVT-1 on cholesterol absorption and LDL cholesterol in humans

Author keywords

Cholesterol; Cholesterol absorption; Cholesterol esterase; Clinical trial; Mass spectrometry

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTERASE; ENZYME INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PANCREAS ENZYME; SODIUM CELLULOSE SULFATE; TRACER; UNCLASSIFIED DRUG;

EID: 0032881789     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007864208932     Document Type: Article
Times cited : (9)

References (22)
  • 1
    • 0000408797 scopus 로고
    • Absolute requirement for free sterol for absorption by rat intestinal mucosa
    • Vahouny GV, Treadwell CR. Absolute requirement for free sterol for absorption by rat intestinal mucosa. Proc Soc Exp Biol Med 1964;116:496-498.
    • (1964) Proc Soc Exp Biol Med , vol.116 , pp. 496-498
    • Vahouny, G.V.1    Treadwell, C.R.2
  • 2
    • 0000303609 scopus 로고
    • Role of bile and pancreatic juice in cholesterol absorption and esterification
    • Borja CR, Vahouny GV, Treadwell CR. Role of bile and pancreatic juice in cholesterol absorption and esterification. Am J Physiol 1964;206:223-228.
    • (1964) Am J Physiol , vol.206 , pp. 223-228
    • Borja, C.R.1    Vahouny, G.V.2    Treadwell, C.R.3
  • 3
    • 0021211108 scopus 로고
    • Cholesterol absorption in rat intestine: Role of cholesterol esterase and acyl coenzyme A:cholesterol acyltransferase
    • Gallo LL, Clark SB, Myers S, Vahouny GV. Cholesterol absorption in rat intestine: Role of cholesterol esterase and acyl coenzyme A:cholesterol acyltransferase. J Lipid Res 1984;25:604-612.
    • (1984) J Lipid Res , vol.25 , pp. 604-612
    • Gallo, L.L.1    Clark, S.B.2    Myers, S.3    Vahouny, G.V.4
  • 4
    • 0027434874 scopus 로고
    • Cholesterol transport function of pancreatic cholesterol esterase: Directed sterol uptake and esterification in enterocytes
    • Lopez-Candales A, Bosner MS, Spilburg CA, Lange LG. Cholesterol transport function of pancreatic cholesterol esterase: Directed sterol uptake and esterification in enterocytes. Biochemistry 1993;32:12085-12089.
    • (1993) Biochemistry , vol.32 , pp. 12085-12089
    • Lopez-Candales, A.1    Bosner, M.S.2    Spilburg, C.A.3    Lange, L.G.4
  • 6
    • 0020308623 scopus 로고
    • The role of cholesteryl ester hydrolysis and synthesis in cholesterol transport across rat intestinal mucosal membrane. A new concept
    • Bhat SG, Brockman HL. The role of cholesteryl ester hydrolysis and synthesis in cholesterol transport across rat intestinal mucosal membrane. A new concept. Biochem Biophys Res Comm 1982;109:486-492.
    • (1982) Biochem Biophys Res Comm , vol.109 , pp. 486-492
    • Bhat, S.G.1    Brockman, H.L.2
  • 7
    • 0019412208 scopus 로고
    • The effect of pancreatic diversion on lymphatic absorption and esterification of cholesterol in the rat
    • Watt SM, Simmonds WJ. The effect of pancreatic diversion on lymphatic absorption and esterification of cholesterol in the rat. J Lipid Res 1981;22:157-165.
    • (1981) J Lipid Res , vol.22 , pp. 157-165
    • Watt, S.M.1    Simmonds, W.J.2
  • 8
    • 0025642582 scopus 로고
    • Metabolic fate of pancreas-derived cholesterol esterase in intestine: An in vitro study using caco-2 cells
    • Huang Y, Hui DY. Metabolic fate of pancreas-derived cholesterol esterase in intestine: An in vitro study using Caco-2 cells. J Lipid Res 1990;31:2029-2037.
    • (1990) J Lipid Res , vol.31 , pp. 2029-2037
    • Huang, Y.1    Hui, D.Y.2
  • 9
    • 0029066878 scopus 로고
    • Role of bile salt-dependent cholesteryl ester hydrolase in the uptake of micellar cholesterol by intestinal cells
    • Shamir R, Johnson WJ, Zolfaghari R, Lee HS, Fisher EA. Role of bile salt-dependent cholesteryl ester hydrolase in the uptake of micellar cholesterol by intestinal cells. Biochemistry 1995;34:6351-6358.
    • (1995) Biochemistry , vol.34 , pp. 6351-6358
    • Shamir, R.1    Johnson, W.J.2    Zolfaghari, R.3    Lee, H.S.4    Fisher, E.A.5
  • 10
    • 0028824083 scopus 로고
    • Identification of a species specific regulatory site in human pancreatic cholesterol esterase
    • Spilburg C, Cox DG, Wang X Bernat BA, Bosner MS, Lange LG III. Identification of a species specific regulatory site in human pancreatic cholesterol esterase. Biochemistry 1995;34:15532-15538.
    • (1995) Biochemistry , vol.34 , pp. 15532-15538
    • Spilburg, C.1    Cox, D.G.2    Wang, X.3    Bernat, B.A.4    Bosner, M.S.5    Lange L.G. III6
  • 11
    • 0016275140 scopus 로고
    • Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats
    • Zilversmit DB, Hughes LB. Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats. J Lipid Res 1974;15:465-473.
    • (1974) J Lipid Res , vol.15 , pp. 465-473
    • Zilversmit, D.B.1    Hughes, L.B.2
  • 12
    • 0020324604 scopus 로고
    • Further validation of the plasma isotope ratio method for measurement of cholesterol absorption
    • Samuel P, McNamara DJ, Ahrens EH Jr., Crouse JR, Parker T. Further validation of the plasma isotope ratio method for measurement of cholesterol absorption. J Lipid Res 1982; 23:480-489.
    • (1982) J Lipid Res , vol.23 , pp. 480-489
    • Samuel, P.1    McNamara, D.J.2    Ahrens E.H., Jr.3    Crouse, J.R.4    Parker, T.5
  • 14
    • 10544227750 scopus 로고    scopus 로고
    • Quantification of cholesterol tracers by gas chromatography/negative ion chemical ionization mass spectrometry
    • Ostlund RE Jr, Hsu F-F, Bosner MS, Stenson WF, Hachey DL. Quantification of cholesterol tracers by gas chromatography/negative ion chemical ionization mass spectrometry. J Mass Spectrometry 1996;31:1291-1296.
    • (1996) J Mass Spectrometry , vol.31 , pp. 1291-1296
    • Ostlund R.E., Jr.1    Hsu, F.-F.2    Bosner, M.S.3    Stenson, W.F.4    Hachey, D.L.5
  • 15
    • 0032913411 scopus 로고    scopus 로고
    • Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry
    • Bosner MS, Lange LG, Stenson WF, Ostlund RE Jr. Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry. J Lipid Res 1999;40:302-308.
    • (1999) J Lipid Res , vol.40 , pp. 302-308
    • Bosner, M.S.1    Lange, L.G.2    Stenson, W.F.3    Ostlund R.E., Jr.4
  • 16
    • 0003544918 scopus 로고
    • Manual of Laboratory Operations, DHEW Publication no. NIH 75-628, United States Government Printing Office, Washington, D.C.
    • Manual of Laboratory Operations. Lipid Research Clinics Program. DHEW Publication no. NIH 75-628.1974. United States Government Printing Office, Washington, D.C.
    • (1974) Lipid Research Clinics Program
  • 17
    • 0014254327 scopus 로고
    • Turnover of plasma cholesterol in man
    • Goodman DS, Noble RP. Turnover of plasma cholesterol in man. J Clin Invest 1968;47:231-241.
    • (1968) J Clin Invest , vol.47 , pp. 231-241
    • Goodman, D.S.1    Noble, R.P.2
  • 18
    • 0029989318 scopus 로고    scopus 로고
    • Dietary free und esterified cholesterol absorption in cholesterol esterase (bile salt-stimulated lipase) gene-targeted mice
    • Howles PN, Carter CP, Hui, DY. Dietary free und esterified cholesterol absorption in cholesterol esterase (bile salt-stimulated lipase) gene-targeted mice. J Biol Chem 1996; 271:7196-7202.
    • (1996) J Biol Chem , vol.271 , pp. 7196-7202
    • Howles, P.N.1    Carter, C.P.2    Hui, D.Y.3
  • 19
    • 0020581405 scopus 로고
    • β-sitosterol: Esterification by intestinal acycoenzyme A:cholesterol acyltransferase (ACAT) and its effect on cholesterol esterification
    • Field FJ, Mathur SN. β-Sitosterol: Esterification by intestinal acycoenzyme A:cholesterol acyltransferase (ACAT) and its effect on cholesterol esterification. J Lipid Res 1983; 24:409-417.
    • (1983) J Lipid Res , vol.24 , pp. 409-417
    • Field, F.J.1    Mathur, S.N.2
  • 20
    • 0022256566 scopus 로고
    • Role of acyl-coA:Cholesterol acyltransferase in cellular cholesterol metabolism
    • Suckling KE, Stange EF. Role of acyl-coA:cholesterol acyltransferase in cellular cholesterol metabolism. J Lipid Res 1985;26:647-671.
    • (1985) J Lipid Res , vol.26 , pp. 647-671
    • Suckling, K.E.1    Stange, E.F.2
  • 22
    • 0025259298 scopus 로고
    • Uptake of cholesterol by small intestinal brush border membrane is protein-mediated
    • Thurnhofer H, Hauser H. Uptake of cholesterol by small intestinal brush border membrane is protein-mediated. Biochemistry 1990;29:2142-2148.
    • (1990) Biochemistry , vol.29 , pp. 2142-2148
    • Thurnhofer, H.1    Hauser, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.