Cholinergic induced mesenteric vasorelaxation in response to head-up tilt

Acta Physiologica Scandinavica

Volumn 166, Issue 4, 1999, Pages 279-284

  Perko, Mario J ^a   Madsen, P ^b   Perko, G ^b   Schroeder, T V ^a   Secher, N H ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NONE

Author keywords

Blood flow; Duplex ultrasound; Hypotension; Hypovolaemia

Indexed keywords

ADULT; ARTERY BLOOD FLOW; ARTERY RESISTANCE; ARTICLE; BLOOD FLOW VELOCITY; CHOLINERGIC RECEPTOR BLOCKING; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; FEMALE; HEAD TILTING; HUMAN; HUMAN EXPERIMENT; HYPOTENSION; HYPOTHESIS; HYPOVOLEMIA; MALE; NORMAL HUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; REST; SUPERIOR MESENTERIC ARTERY; VASODILATATION;

ADULT; BLOOD PRESSURE; CHOLINERGIC ANTAGONISTS; FEMALE; GLYCOPYRROLATE; HEART RATE; HUMANS; HYPOTENSION; MALE; MESENTERIC ARTERY, SUPERIOR; PARASYMPATHETIC NERVOUS SYSTEM; POSTPRANDIAL PERIOD; POSTURE; STROKE VOLUME; VASCULAR RESISTANCE; VASODILATION;

EID: 0032881752     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201x.1999.00568.x     Document Type: Article

References (23)

1. Aars, H., Brodin, P. & Andersen, E. 1993. A study of cholinergic and beta-adrenergic components in the regulation of blood flow in the tooth pulp and gingiva in man. Acta Physiol Scand 148, 441-447.
2. Appel, P.L., Kram, H.B., Mackabce, J., Fleming, A.W. & Shoemaker, W.C. 1986. Comparison of measurements of cardiac output by bioimpedance and thermodilution in severely ill surgical patients. Crit Care Med 14, 933-935.
3. Evans, D.H., McDicken, W.N., Skidmore, R. & Wodcock, J.P. 1989. Doppler Ultrasound. Physics, Instrumentation, and Clinical Applications, pp. 162-205. John Wiley & Sons, New York, NY.
4. Fondacaro, J.D. 1984. Intestinal blood flow and motility. In: A.P. Shepherd, D.N. Granger (eds) Physiology of the Intestinal Circulation pp. 107-120. Raven Press, New York.
5. Jäger, K., Muench, R., Seifert, H., Beglinger, C., Bollinger, A. & Fisher, J.A. 1990. Calcitonin gene-related peptide (CGRP) causes redistribution of blood flow in humans. Eur J Clin Pharmacol 39, 491-494.
6. Kawasaki, H., Takasaki, K., Saito, A. & Goto, K. 1988. Calcitonin gene-related peptide acts as a novel vasodilator neurotransmitter in mesenteric resistance vessels of the rat. Nature 335, 164-167.
7. Madsen, P., Svendsen, L.B., Jorgensen, L.G., Jansen, S.E. & Secher, N.H. 1998. Tolerance to head-up tilt and suspension with elevated legs. Aviation, Space, Enviromental Med 69, 1-4.
8. Matzen, S., Schifter, S., Radvansky, J., Knigge, U., Warberg, J. & Secher, N.H. 1991. Calcitonin gene-related peptide (CGRP) and leg vascular resistance during head-up tilt induced hypovolaemic shock in man. Acta Physiol Scand 142, 313-318.
9. McDicken, W.N. 1991. Diagnostic Ultrasonics. Principles and Use of Instruments, pp. 203-214. Churchill Livingstone, Edinburgh.
10. Pawelczyk, J.A., Matzen, S., Friedman, D.B. & Secher, N.H. 1994. Cardiovascular and hormonal responses to central hypovolemia in humans. In: N.H. Secher, J.A. Pawelczyk, & J. Lundbrook (eds) Blood Loss and Shock, pp. 25-37. Edward Arnold, London.
11. Perko, M.J., Just, S. & Schroeder, T.V. 1997b. Importance of diastolic velocities in the detection of celiac and mesenteric artery disease by duplex ultrasound. J Vasc Surg 26, 288-293.
12. Perko, M.J., Madsen, P., Perko, G., Schroeder, T.V. & Secher, N.H. 1997a. Mesenteric artery response to the head-up tilt induced central hypovolaemia and hypotension. Clin Physiol 17, 487-496.
13. Perko, M.J., Madsen, P., Perko, G. & Secher, N.H. 1998b. Cholinergic blockade and the mesenteric artery response to the head-up tilt induced central hypovolaemia. Clin Physiol 18, 125-130.
14. Perko, M.J., Nielsen, H.B., Skak, C., Clemmesen, J.O., Schroeder, T.V. & Secher, N.H. 1998a. Mesenteric, coeliac and splanchnic blood flow during exercise. J Physiol, 513 3, 907-913.
15. Perko, M.J., Perko, G., Just, S., Secher, N.H. & Schroeder, T.V. 1996. Changes in superior mesenteric artery Doppler waveform during reduction of cardiac stroke volume and hypotension. Ultrasound Med Biol 22, 11-18.
16. Sander-Jensen, K., Mehlsen, J., Stadeager, C. et al. 1988. Increase in vagal activity during hypotensive lower-body negative pressure in humans. Am J Physiol 255, R149-R156.
17. Sander-Jensen, K., Secher, N.H., Astrup, A. et al. 1986a. Hypotension induced by passive head-up tilt: endocrine and circulatory mechanisms. Am J Physiol 251, R742-R748.
18. Sander-Jensen, K., Secher, N.H., Bic, P., Warberg, J. & Schwartz, T.W. 1986b. Vagal slowing of the heart during haemorrhage: observations from 20 consecutive hypotensive patients. Br Med J 292, 364-366.
19. Sanders, J.S., Mark, A.L. & Ferguson, D.W. 1989. Evidence for cholinergically mediated vasodilation at the beginning of isometric exercise in humans. Circulation 79, 815-824.
20. Sieber, C., Beglinger, C., Jaeger, K., Hildebrand, P. & Stalder, G.A. 1991. Regulation of postprandial mesenteric blood flow in humans: evidence for a cholinergic nervous reflex. Gut 32, 361-366.
21. Walus, K.M., Fondacaro, J.D. & Jacobson, E.D. 1981a. Hemodynamic and metabolic changes during stimulation of ileal motility. Dig Dis Sci 26, 1069-1077.
22. Walus, K.M. & Jacobson, E.D. 1981. Relation between small intestine motility and circulation. Am J Physiol 241, G1-G15.
23. Wong, D.H., Tremper, K.K., Stemmer, E.A. et al. 1990. Noninvasive cardiac output: simultaneous comparison of two different methods with thermodilution. Anesthesiology 72, 4-12.