Tyrosine kinase A-nerve growth factor receptor is antigenically present in dystrophic neurites from a variety of conditions but not in Alzheimer's disease

Neuroscience Letters

Volumn 273, Issue 1, 1999, Pages 67-71

  Marinelli, L ^a   Cammarata, S ^a   Nobbio, L ^a   Schenone, A ^a   Zaccheo, D ^a   Angelini, G ^b   Tabaton, M ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Alzheimer' s disease; Amyloid; Amyloid protein; Nerve growth factor; Neurodegeneration; Tyrosine kinase A; Ubiquitin

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; NERVE GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UBIQUITIN;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE DEGENERATION; PRIORITY JOURNAL; PYRAMIDAL TRACT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; AIDS DEMENTIA COMPLEX; ALZHEIMER DISEASE; CEREBRAL CORTEX; CEREBRAL INFARCTION; CYSTIC FIBROSIS; HUMANS; IMMUNOHISTOCHEMISTRY; MUSCULAR DYSTROPHIES; NEUROFIBRILLARY TANGLES; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SENILE PLAQUES; UBIQUITINS;

EID: 0032881449     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00625-4     Document Type: Article

References (21)

1. Bertrand P., Roger O., Houlgatte R., Javoi-Agid F., Brandel J.P., Doble A., Blanchard J.C. Measurement of nerve growth factor-like immunoreactivity in the human brain using an anti-mouse-NGF enzyme immunoassay. Neurochem. Int. 20:1992;215-218.
2. Buell S.J., Coleman P.D. Dendritic growth in the aged human brain and failure of growth in senile dementia. Science. 206:1979;854-856.
3. Cochran E., Bacci B., Chen Y., Patton A., Gambetti P., Autilio-Gambetti L. Amyloid precursor protein and ubiquitin immunoreactivity in dystrophic axons is not unique to Alzheimer's disease. Am. J. Pathol. 139:1991;485-489.
4. Davies P., Maloney A.J. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet. 2:1976;1403.
5. Dickson D.W., Wertkin A., Kress Y., Ksiezak-Reding H., Yen S.H. Ubiquitin immunoreactive structures in normal human brains: distribution and developmental aspects. Lab. Invest. 63:1990;87-99.
6. + channels and suppression of neuronal activity by secreted β-amyloid precursor protein. Nature. 379:1996;74-78.
7. Geddes J.W., Anderson K.J., Cotman C.W. Senile plaques as aberrant sprout-stimulating structures. Exp. Neurol. 94:1986;767-776.
8. Goedert M., Fine A., Hunt S.P., Ullrich A. Nerve growth factor mRNA in the peripheral and central rat tissues and in human brain: normal levels in basal forebrain in Alzheimer's disease. Brain. Res. 1:1986;85-92.
9. Gonatas N.K., Anderson A., Evangelista I. The contribution of altered synapses in the senile plaque: an electronmicroscopic study in Alzheimer's dementia. J. Neuropathol. Exp. Neurol. 26:1967;25-39.
10. Heumann R. Neurotrophin signalling. Curr. Opin. Neurobiol. 4:1994;668-679.
11. Hock C., Heese K., Muller-Spahn F., Hulette C., Rosenberg C., Otten U. Decreased TrkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease. Neurosci. Lett. 241:1998;151-154.
12. Knusel B., Rabin S.J., Hefti F., Kaplan D.R. Regulated neurotrophin receptor responsiveness during neuronal migration and early differentiation. J. Neurosci. 14:1994;1542-1554.
13. Lindsay R.M., Wiegand S.J., Altar C.A., Di Stefano P.S. Neurotrophic factors: from molecule to man. Trends Neurosci. 17:1994;182-190.
14. Lindvall O., Kokaia Z., Bengzon J., Elmer E., Kokaia M. Neurotrophins and brain insults. Trends Neurosci. 17:1994;490-496.
15. Lucidi-Phillipi C.A., Clary D.O., Reichardt L.F., Gage F.H. TrkA activation is sufficient to rescue axotomized cholinergic neurons. Neuron. 16:1996;653-663.
16. Mobley W.C., Neve R.L., Prusiner S.B., McKinley M.P. Nerve growth factor increases mRNA levels for the prion protein and the β-amyloid protein precursor in developing hamster brain. Proc. Natl. Acad. Sci. USA. 85:1988;9811-9815.
17. Mufson E.J., Lavine N., Jaffar S., Kordower J.H., Quirion R., Saragovi H.U. Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease. Exp. Neurol. 146:1997;91-103.
18. Schenone A., Gill J.S., Zacharias D.A., Windebank A.J. Expression of high- and low-affinity neurotrophin receptors on human transformed lymphocytes. J. Neuroimmunol. 64:1996;141-149.
19. Seitelberger F. Neuropathological conditions related to neuroaxonal dystrophy. Acta Neuropathol. (Berl.). V (Suppl.):1971;17-29.
20. Tabaton M., Mandybur T.I., Perry G., Onorato M., Autilio-Gambetti L., Gambetti P. The widespread alteration of neurites in Alzheimer disease may be unrelated to amyloid deposition. Ann. Neurol. 26:1989;771-778.
21. Whitehouse P.J., Price D.L., Clark A.W., Coyle J.T., DeLong M.R. Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann. Neurol. 10:1981;122-126.