Neuronal regulation: A biologically plausible mechanism for efficient synaptic pruning in development

Neurocomputing

Volumn 26-27, Issue , 1999, Pages 633-639

  Chechik, Gal ^a   Meilijson, Isaac ^a   Ruppin, Eytan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Brain development; Neuronal regulation; Synaptic pruning; Weight normalization

Indexed keywords

BIOELECTRIC POTENTIALS; BIOLOGICAL MEMBRANES; MEDICAL COMPUTING; NEUROPHYSIOLOGY;

BRAIN DEVELOPMENT; NEURONAL REGULATION; SYNAPTIC PRUNING; WEIGHT NORMALIZATION;

BRAIN;

ARTICLE; BRAIN DEVELOPMENT; HOMEOSTASIS; MATHEMATICAL MODEL; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL EXCITABILITY; NERVE CELL INHIBITION; NERVE CELL MEMBRANE POTENTIAL; PRIORITY JOURNAL; REGULATORY MECHANISM; SYNAPSE; SYNAPTIC INHIBITION;

EID: 0032880320     PISSN: 09252312     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-2312(98)00161-1     Document Type: Article

References (9)

1. G. Chechik, I. Meilijson, E. Ruppin, Synaptic pruning during development: a novel account in neural terms, Proceedings of the Sixth Annual Computational Neurosciene Meeting (CNS97), Big Sky, Montana. 1997.
2. G. Chechik, I. Meilijson, E. Ruppin, Synaptic pruning during development: a computational account, Neural Comput. 10 (7) (1998).
3. Colman H., Nabekura J., Lichtman J.W. Alterations in synaptic strength preceding axon withdrawal. Science. 275:1997;356-361.
4. Horn D., Levy N., Ruppin E. Synaptic maintenance via neuronal regulation. Neural Comput. 10(1):1998;1-18.
5. Rakic P., Bourgeois J.P., Goldman-Rakic P.S. Synaptic development of the cerebral cortex. implications for learning, memory and mental illness Prog. Brain Res. 102:1994;227-243.
6. P.E. Roland, Brain Activation, Wiley-Liss, New York, 1993.
7. Tsodyks M.V., Feigel'man M. Enhanced storage capacity in neural networks with low activity level. Europhys. Lett. 6:1988;101-105.
8. Turrigano G.G., Leslie K., Desai N., Nelson S.B. Activity dependent scaling of quantal amplitude in neocortical pyramidal neurons. Nature. 391(6670):1998;892-896.
9. J.R. Wolff, R. Laskawi, W.B. Spatz, M. Missler, Structural dynamics of synapses and synaptic components, Behavioral Brain Res. 66 (1-2) (1995) 13-20.