A minimal model for metabotropic modulation of fast synaptic transmission and firing properties in bullfrog sympathetic B neurons

Neurocomputing

Volumn 26-27, Issue , 1999, Pages 255-262

  Schobesberger, Hermann ^a   Gutkin, Boris S ^a   Horn, John P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

M current; Muscarinic; Nicotinic

Indexed keywords

CELLS; COMPUTER SIMULATION; IONIC CONDUCTION; POTASSIUM; PROTEINS;

M-CURRENT; MUSCARINIC; NICOTINIC;

BRAIN;

METABOTROPIC RECEPTOR; MUSCARINIC RECEPTOR; NICOTINIC RECEPTOR;

ACTION POTENTIAL; ARTICLE; BULLFROG; EXCITATORY POSTSYNAPTIC POTENTIAL; MATHEMATICAL MODEL; NONHUMAN; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; SYMPATHETIC BLOCKING; SYMPATHETIC NERVE; SYNAPTIC TRANSMISSION;

EID: 0032880318     PISSN: 09252312     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-2312(99)00019-3     Document Type: Article

References (8)

1. Adams P.R., Brown D.A. Synaptic inhibition of the M-current. slow excitatory post-synaptic potential mechanism in bullfrog sympathetic neurones J. Physiol. 332:1982;263-272.
2. Jones S.W. On the resting potential of isolated frog sympathetic neurons. Neuron. 3:1989;153-161.
3. Jones S.W., Adams P.R. The M-current and other potassium currents of vertebrate neurons. Kaczmarek L.K., Levitan I.B. Neuromodulation: The Biochemical Control of Neuronal Excitability. 1987;159-186 Oxford University Press, New York.
4. Karila P., Horn J.P. Strength and modulation of secondary nicotinic synapses on sympathetic B neurons. Soc. Neurosci. Abstr. 24:1998;1812.
5. Marrion N. Control of M-current. Annu. Rev. Physiol. 59:1997;483-504.
6. Schobesberger H., Horn J.P. Modulatory efficacy of M-current suppression depends upon selectivity of the leak conductance. Soc. Neurosci. Abstr. 24:1998;1812.
7. Shen W.-X., Horn J.P. A presynaptic mechanism accounts for the differential block of nicotinic synapses on sympathetic B and C neurons by d-tubocurarine. J. Neurosci. 15:1995;5025-5035.
8. Yamada W.M., Koch C., Adams P. Multiple channels and calcium dynamics-modeling bullfrog sympathetic ganglion cells. Koch C., Segev I. Methods in Neuronal Modeling from Synapses to Networks. 1989;97-133 MIT Press, Cambridge.