Determination of the glomerular filtration rate (GFR): Methodological problems, age-dependence, consequences of various surgical interventions, and the influence of different drugs and toxic substances

Physiological Research

Volumn 48, Issue 4, 1999, Pages 267-279

  Fleck, C ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Age; Amino acid load; Bile duct ligation; Cyclosporine A; Dexamethasone; Diltiazem; Epidermal growth factor; Furosemide; Heavy metal nephrotoxicity; Inulin; Kidney; Nephrectomy; Postnatal development; Rat; Renal ischemia; Triiodothyronine

Indexed keywords

4 AMINOHIPPURIC ACID; AMINO ACID; CYCLOSPORIN; DEXAMETHASONE; DICHROMATE SODIUM; DILTIAZEM; EPIDERMAL GROWTH FACTOR; FLUORESCEIN ISOTHIOCYANATE; FUROSEMIDE; HEAVY METAL; IMIDAZOLE; INULIN; LIOTHYRONINE; SANDIMMUN OPTORAL; THALLIUM SULFATE; TIRACIZINE; UNCLASSIFIED DRUG;

ADOLESCENT; AGE; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GLOMERULUS FILTRATION RATE; HEPATORENAL SYNDROME; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CLEARANCE; KIDNEY ISCHEMIA; KIDNEY TUBULE ABSORPTION; NEPHRECTOMY; NEPHROTOXICITY; NEWBORN; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

AGING; ANIMALS; CYCLOSPORINE; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; GLOMERULAR FILTRATION RATE; HUMANS; INULIN; KIDNEY; KIDNEY DISEASES; KINETICS; METALS; NEPHRECTOMY; RATS; RATS, WISTAR; SPECIES SPECIFICITY; UREMIA;

EID: 0032879513     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. ANKERMANN H, BRÄUNLICH H, HOFFMANN H, KLINGER W, SPLINTER FK, TRAEGER A: Entwicklungspharmakologie. Fischer, Stuttgart, 1974, pp 11-17.
2. APPENROTH D, FRÖB S, KERSTEN L, SPLINTER FK, WINNEFELD K: Protective effects of vitamin E and C on cisplatin nephrotoxicity in developing rats. Arch Toxicol 71: 677-683, 1997.
3. BADR KF, MURRAY JJ, BREYER MD, TAKAHASHI, K, INAGAMI, T, HARRIS, RC: Mesangial cell, glomerular, and renal vascular responses to endothelin in the rat kidney. J Clin Invest 83: 336-342, 1989.
4. BALINT P, LASZLO K: Effect of imidazole and indomethacin on hemodynamics of the obstructed canine kidney. Kidney Int 27: 892-897, 1985.
5. 2 receptors: characterization and functional significance. Am J Physiol 235: F570-F575, 1978.
6. BAYLIS C, BRENNER WM: Mechanism of the glucocorticoid-induced increase in glomerular filtration rate. Am J Physiol 234: F166-F170, 1978.
7. BAYLIS C, DEEN WM, MYERS BD, BRENNER BM: Effect of some vasodilator drugs on transcapillary fluid exchange in renal cortex. Am J Physiol 230: 1148-1158, 1976.
8. BAYLIS C, MITRUKA B, DENG A: Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 90: 278-281, 1992.
9. BRÄUNLICH H, KÖHLER A, SCHMIDT I: Acceleration of p-aminohippurate excretion in immature rats by dexamethasone treatment. Med Biol 64: 267-270, 1986a.
10. BRÄUNLICH H, STEIN G, LASKE V, FLECK, C, KEIL E, KERSTEN L, MÜLLER A: Renal effects of aluminium in uraemic rats and in rats with intact kidney function. J Appl Toxicol 6: 55-59, 1986b.
11. BRÄUNLICH H, SPROTT H, APPENROTH D, FLECK C, MÜLLER A, STEIN G: Nephrotoxicity of chromate in rats with impaired kidney function. Trace Elem Med 9: 130-135, 1992.
12. CAVARAPE A, ENDLICH K, FELETTO F, PAREKH N, BARTOLI E, STEINHAUSEN M: Contribution of endothelin receptors in renal microvessels in acute cyclosporine-mediated vasoconstriction in rats. Kidney Int 53: 963-969, 1998.
13. DONADIO C, LUCCHESI A, TRAMONTI G, BIANCHI C: Creatinine clearance predicted from body cell mass is a good indicator of renal function. Kidney Int 52 (Suppl 63): S166-S168, 1997.
14. EPSTEIN M: The kidney in liver disease. In: Liver Biology and Pathobiology, 3rd ed., IM ARIAS, WB JACOBY, H POPPER, D SCHACHTER, DA SHAFRITZ (eds), Raven Press, New York, 1994, pp 1235-1256.
15. FIELD LJ, VERESS AT, STEINHELPER ME, COCHRANE K, SONNEBERG H: Kidney function in ANF-transgenic mice: effect of blood volume expansion. J Physiol Lond 260: 1-5, 1991.
16. FINE A: The effects of amino acid loading on glomerular filtration in dogs on different protein diets: a controlled study. Can J Physiol Pharmacol 8: 993-996, 1988.
17. FISHER DA, SALIDO EC, BARAJAS L: Epidermal growth factor and the kidney. Annu Rev Physiol 51: 67-80, 1989.
18. FLECK C, APPENROTH D: Renal amino acid transport in immature and adult rats during thallium-induced nephrotoxicity. Toxicology 106: 229-236, 1996.
19. FLECK C, BRÄUNLICH H: Wiederherstellung von Clearanceleistungen bei der Ratte nach einseitiger Nephrektomie. Z Versuchstierk 23: 13-23, 1981.
20. FLECK C, BRÄUNLICH H: Kidney function after unilateral nephrectomy. Exp Pathol 25: 3-18, 1984.
21. FLECK C, BRÄUNLICH H: Relation between renal and hepatic excretion of drugs: III. Comparison of various methods reducing the renal or hepatic excretory capacity of rats. Exp Pathol 31: 95-110, 1987.
22. FLECK C, BRÄUNLICH H: Interrelationship between excretion of drugs via urine and bile. In: Biliary Excretion of Drugs and Other Chemicals. CP SIEGERS, JB WATKINS III (eds), Fischer, Stuttgart, 1991, pp.511-529.
23. FLECK C, BRÄUNLICH H: Renal handling of drugs and amino acids after impairment of kidney or liver function. Influences of maturity and protective treatment. Pharmacol Ther 67: 53-77, 1995.
24. FLECK C, PERTSCH J: Epidermal growth factor (EGF) increases the renal transport of amino acid in amino acid loaded rats. Amino Acids 15: 307-320, 1998.
25. FLECK C, REZNIK LV, POKROVSKI VG: Effectivity of furosemide in foetal and neonatal rats. Zbl Pharmazie 122: 1307-1310, 1983.
26. FLECK C, RICHTER S, TISCHENDORF G, KLEMM W, BRÄUNLICH H: Relation between renal and hepatic excretion of drugs. XIII. Pharmacokinetics of new antiarrhythmic drug Bonnecor in rats with normal and impaired excretory functions. Exp Pathol 36: 165-175, 1989.
27. FLECK C, HAUBOLD D, HILLMANN T, MÖCKEL H, MÖCKEL M, BRÄUNLICH H: Evaluation of methods indicating higher susceptibility of immature rats to renal ischaemia. Exp Toxicol Pathol 45: 155-160, 1993.
28. FLECK C, AURICH M, SCHWERTFEGER M: Stimulation of renal amino acid reabsorption after treatment with triiodothyronine or dexamethasone in amino acid loaded rats. Amino Acids 12: 265-279, 1997.
29. FLECK C, GRÄFE K, KART : Renal handling of amino acid in 5/6-nephrectomized rats: stimulation of renal amino acid reabsorption after treatment with triiodothyronine or dexamethasone under amino acid load. Amino Acids 16: 149-164, 1999.
30. FÜHR J, KACZMARCZYK J, KRÜTTGEN CD: Eine einfache colorimetrische Methode zur Inulin-Bestimmung für Nieren-Clearance-Untersuchungen bei Stoffwechselgesunden und Diabetikern. Klin Wschr 33: 729-739, 1955.
31. GOUYON JB, VALLOTTON M, GUIGNARD JP: The new-born rabbit: a model for studying hypoxemia-induced renal changes. Biol Neonate 52: 115-120, 1987.
32. HAGEMANN I, WÜSTENBERG PW: Methoden zur Bestimmung der glomerulären Filtrationsrate (GFR) in Versuchen an Kleintieren: Positionsbericht der Arbeitsgruppe "Tierexperimentelle Nierenfunktions-diagnostik" der Gesellschaft für Nephrologie der DDR. Z Urol Nephrol 80: 605-609, 1987.
33. HARRIS RC, HOOVER RL, JACOBSON HR, BADR KF: Evidence for glomerular actions of epidermal growth factor in the rat. J Clin Invest 82: 1028-1039, 1988.
34. IDO Y, TILTON RG, CHANG K, PUGLIESE G, WILLIAMSON JR: Rapid measurement of glomerular filtration rate in small animals. Kidney Int 41: 435-439, 1992.
35. JOHNSON V, SPITZER A: Renal reabsorption of phosphate during development: whole-kidney events. J Physiol Lond 251: 151-156, 1986.
36. KAUFMAN CF, BERGMANN EN: Renal function studies in normal and toxaemic pregnant sheep. Cornell Vet 68: 124-137, 1978.
37. KEISER JA, RYAN MJ: Hemodynamic effects of epidermal growth factor in conscious rats and monkeys. Proc Natl Acad Sci USA 93: 4957-4961, 1996.
38. KLINGER W : Biotransformation of drugs and other xenobiotics during postnatal development. Exp Toxicol Pathol 48 (Suppl. 1): 1-68, 1996.
39. KUHN U, LUPP A, KOSTKA E, KÜHL A, BALOGH A, STEIN G, FLECK C: The influence of diltiazem on cyclosporine A-levels and monooxygenases function in rats. Exp Toxicol Pathol 48 (Suppl II): 211-214, 1996.
40. KUHN U, LUPP A, KOSTKA E, KÜHL A, BALOGH A, STEIN G, FLECK C: Is there a beneficial effect of the calcium channel blocker diltiazem on cyclosporine A nephrotoxicity in rats? Exp Toxicol Pathol 50: 484-490, 1998.
41. KUROKAWA K: Tubuloglomerular feedback: its physiological and pathophysiological significance. Kidney Int 54 (Supp 67): S71-S74, 1998.
42. LINK L, WEIDMANN P, PROBST P, FUTTERLIEB A: Renal handling of norepinephrine and epinephrine in the pig. Pflügers Arch 405: 66-69, 1985.
43. LORTHOLARY O, BLANCHAET F, NOCHY D, HEUDES D, SETA N, AMIRAULT P, CARBON C: Effect of diltiazem on netilmicin-induced nephrotoxicity in rabbits. Antimicrob Agents Chemother 37: 1790-1798, 1993.
44. LUSTGARTEN JA, WENK RE: A simply rapid kinetic method for serum creatinine measurements. Clin Chem 18: 1419-1422, 1972.
45. MADDOX DA, BRENNER BA: Glomerular ultrafiltration. In: The Kidney, Vol. 1, BM BRENNER, SA LEVINE (eds), Saunders, Philadelphia, 1996, pp 286-333.
46. 51Cr-EDTA and endogenous creatinine clearances in the pig. Acta Physiol Scand 161: 253-260, 1997.
47. SCHLONDORFF D, GOLDWASSER P, NEUWIRTH R, SATRIANO, JA, CLAY, KL: Production of platelet activating factor in glomerulus and cultured glomerular mesangial cells. Am J Physiol 250: F1123-F1127, 1986.
48. SCHMIDT M, MANN JFE, STEIN G, HERTER M, NUSSBERGER J, KLEINBEIL A, RITZ E: Natriuresis-pressure relationship in polycystic kidney disease. J Hypertens 8: 277-283, 1990.
49. SOHTELL M, KALMARK B, ULFENDAHL H: FITC-inulin as a kidney tubule marker in the rat. Acta Physiol Scand 119, 313-316, 1983.
50. SPERSCHNEIDER H, WAGNER C, KORN A, CHRISTIANS U: Effect of diltiazem on concentration of cyclosporine metabolites in Sandimmune and Neoral treated kidney transplant patient. Med Klin 92: 589-596, 1997.
51. TIETZE IN, SORENSEN S, EISKJAER H, THOMSEN K, PETERSEN E: Tubular handling of amino acids after intravenous infusion of amino acids in healthy humans. Nephrol Dial Transplant 7: 493-500, 1992.
52. VALLON V, OSSWALD H, BLANTZ RC, THOMSON S: Luminal signal in tubuloglomerular feedback: what about potassium? Kidney Int 54 (Suppl 67): S177-S179, 1998.
53. 4 in normal and glomerulonephritis kidneys. J Am Soc Nephrol 2: 45-56, 1991.