Plasma 25-Hydroxyvitamin D Responses of Younger and Older Men to Three Weeks of Supplementation with 1800 IU/day of Vitamin D

Journal of the American College of Nutrition

Volumn 18, Issue 5, 1999, Pages 470-474

  Harris, Susan S ^a   Dawson Hughes, Bess ^a   Perrone, Gayle A ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

25 hydroxyvitamin D; Aging; Vitamin D absorption; Vitamin D supplementation

Indexed keywords

25 HYDROXYERGOCALCIFEROL; 25 HYDROXYVITAMIN D; CALCIFEDIOL; ERGOCALCIFEROL;

ADULT; AGED; AGING; ARTICLE; CELL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; FOOD INTAKE; HUMAN; HYDROXYLATION; INTESTINE ABSORPTION; LIVER METABOLISM; MALE; ORAL DRUG ADMINISTRATION; VITAMIN BLOOD LEVEL; VITAMIN D METABOLISM; VITAMIN SUPPLEMENTATION; WINTER;

ABSORPTION; ADULT; AGED; AGING; BODY MASS INDEX; CALCIFEDIOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIETARY SUPPLEMENTS; ERGOCALCIFEROLS; HUMANS; MALE; MIDDLE AGED;

EID: 0032878158     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.1999.10718885     Document Type: Article

References (26)

1. Orwoll ES, Meier DE: Alterations in calcium, vitamin D, and parathyroid hormone physiology in normal men with aging: relationship to the development of senile osteopenia. J Clin Endocrinol Metab 63: 1262-1269, 1986.
2. Omdahl JL, Garry PJ, Hunsaker LA, Hunt WC, Goodwin JS: Nutritional status in a healthy elderly population: vitamin D. Am J Clin Nutr 36: 1125-1233, 1982.
3. Sowers MF, Wallace RB, Hollis BW, Lemke JH: Parameters related to 25-OH-D levels in a population-based study of women. Am J Clin Nutr 43: 621-628, 1986.
4. Bouillon RA, Auwerx JH, Lissens WD, Pelemans WK: Vitamin D status in the elderly: seasonal substrate deficiency causes 1,25-dihydroxycholecalciferol deficiency. Am J Clin Nutr 45: 755-763, 1987.
5. Aksnes L, Rødland O, Ødegaard O, Bakke K, Aarskog D: Serum levels of vitamin D metabolites in the elderly. Acta Endocr 121: 27-33, 1989.
6. Need AG, Morris HA, Horowitz M, Nordin BEC: Effects of skin thickness, age, body fat, and sunlight on serum 25-hydroxyvitamin D. Am J Clin Nutr 58: 882-885, 1993.
7. MacLaughlin J, Holick MF: Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest 76: 1536-1538, 1985.
8. Blomhoff R, Helgerud P, Dueland S, Berg T, Pedersen JI, Norum KR, Drevon CA: Lymphatic absorption and transport of retinol and vitamin D-3 from rat intestine. Evidence for different pathways. Biochimica et Biophysica Acta 772: 109-116, 1984.
9. Gullo L, Ventrucci M, Naldoni P, Pezzilli R: Aging and exocrine pancreatic function. J Am Geriatr Soc 34: 790-792, 1986.
10. Woodhouse KW, Wynne HA: Age-related change in liver size and hepatic blood flow. Clin Pharmacokinet 15: 287-294, 1988.
11. Zoli M, Iervese T, Abbati S, Bianchi GP, Marchesini G, Pisi E: Portal blood velocity and flow in aging man. Gerontology 35: 61-65, 1989.
12. Thrasher JD: Age and the cell cycle of the mouse epithelium. Exper Geront 6: 19-24, 1971.
13. Gorbach SL, Hahas L, Lerner OI, Weinstein L: Studies of intestinal microflora. I. Effects of diet, age, and periodic sampling on numbers of fecal microorganisms in man. Gastroenterology 53: 845-855, 1967.
14. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food, and Nutrition Board, Institute of Medicine: “Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride.” Washington, DC: National Academy Press, 1997.
15. Harris SS, Dawson-Hughes B: Seasonal changes in plasma 25-hydroxyvitamin D concentrations of young American black and white women. Am J Clin Nutr 67: 1232-1236, 1998.
16. Shepard RM, Horst RL, Hamstra AJ, DeLuca HF: Determination of vitamin D and its metabolites in plasma from normal and anephric man. Biochem J 182: 55-69, 1979.
17. Chen TC, Turner AK, Holick MF: Methods for the determination of the circulating concentration of 25-hydroxyvitamin D. J Nutr Biochem 1: 315-319.
18. Mayer E, Schmidt-Gayk H: Interlaboratory comparison of 25-hydroxyvitamin D determination. Mayer E, Schmidt-Gayk H. Clin Chem 30: 1199-1204, 1984.
19. Clemens TL, Zhou X-Y, Myles M, Endres D, Lindsay R: Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. J Clin Endocrinol Metab 63: 656-660, 1986.
20. Holick MF: Vitamin D requirements for the elderly. Clin Nutr 5: 121-129, 1986.
21. Barragry JM, France MW, Corless D, Gupta SP, Switala S, Boucher BJ, Cohen RD: Intestinal cholecalciferol absorption in the elderly and in younger adults. Clin Sci Molecular Med 55: 213-220, 1978.
22. Trang HM, Cole DEC, Rubin LA, Pierratos A, Siu S, Vieth R: Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am J Clin Nutr 68: 854-858, 1998.
23. Guillemant S, Prier A, Guillemant J, Massin JP, Camus JP: [Absorption and metabolism of labelled vitamin D3 in elderly subjects] [French]. Revue du Rhumatisme et des Maladies Osteo-Articulaires 49: 93-98, 1982.
24. Rushton C: Vitamin D hydroxylation in youth and age. Age and Ageing 7: 91-95, 1978.
25. Matsuoka M, Otsuka H, Masuda S, Okano T, Kobayashi T, Takeuchi T, Itokawa Y: Changes in the concentrations of vitamin D and its metabolites in the plasma of healthy subjects orally given physiological doses of vitamin D2 by multivitamin or vitamin D preparations. J Nutr Sci Vitaminol 35: 253-266, 1989.
26. Himmelstein S, Clemens TL, Rubin A, Lindsay R: Vitamin D supplementation in elderly nursing home residents increases 25(OH)D but not 1,25(OH)2D. Am J Clin Nutr 52: 701-706, 1990.