Antisense oligonucleotides to stromelysin mRNA inhibit injury-induced proliferation of arterial smooth muscle cells

Histology and Histopathology

Volumn 14, Issue 4, 1999, Pages 1101-1112

  Hultgardh Nilsson A ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Balloon injury; Phenotypic modulation; Rat; Restenosis; Smooth muscle cells; Stromelysin

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; STROMELYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; MALE; MIGRATION INHIBITION; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; RAT; RESTENOSIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; CAROTID ARTERIES; CELL DIVISION; CELLS, CULTURED; DNA; MALE; MATRIX METALLOPROTEINASE 3; MUSCLE, SMOOTH, VASCULAR; OLIGORIBONUCLEOTIDES, ANTISENSE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

ANIMALIA;

EID: 0032878155     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Aoyagi M., Yamamoto M., Azuma H., Nagashima G., Niima Y., Tamaki M., Hirakawa K. and Yamamoto K. (1998). Immunolocalization of matrix metalloproteinases in rabbit carotid arteries after balloon denudation. Histochem. Cell Biol. 109, 97-102.
2. Assoian R.K. and Marcantonio E.E. (1996). The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis. J. Clin. Invest. 98, 2436-2439.
3. Bendeck M.P., Irvin C. and Reidy M.A. (1996). Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury. Circ. Res. 78, 38-43.
4. Bennett M.R., Anglin S., McEvan J.R., Jagoe R., Newby A.C. and Evan G.I. (1994). Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides. J. Clin. Invest. 93, 820-828.