Bovine brain phosphatidylserine attenuates scopolamine-induced amnesia

Physiology and Behavior

Volumn 67, Issue 4, 1999, Pages 551-554

  Claro, F T ^a   Silva, R H ^a   Frussa Filho, R ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Learning; Memory; Phosphatidylserine; Scopolamine

Indexed keywords

PHOSPHATIDYLSERINE; SCOPOLAMINE;

AMNESIA; ANIMAL MODEL; ARTICLE; BRAIN; CATTLE; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032877120     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(99)00099-2     Document Type: Article

References (25)

1. Aporti F., Borsato R., Calderini G., Rubini R., Toffano G., Zanotti A., Valzelli L., Goldstein L. Age-dependent spontaneous EEG bursts in rats. Effects of brain phosphatidylserine Neurobiol. Aging. 7:1986;115-120.
2. Bliss T.V.P., Collingridge G.L. A synaptic model of memory. Long term potentiation in the hippocampus Nature. 361:1993;31-39.
3. Casamenti F., Scali C., Pepeu G. Phosphatidylserine reverses the age-dependent decrease in cortical acetylcholine release. A microdialysis study Eur. J. Pharmacol. 194:1991;11-16.
4. Cenacchi T., Bertoldin T., Farina C., Fiori M.G., Crepaldi G. Cognitive decline in the elderly. A double-blind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration Aging Clin. Exp. Res. 5:1993;123-133.
5. Crook T., Petrie W., Wells C., Massari D.C. Effects of phosphatidylserine in Alzheimer's Disease. Psychopharmacol. Bull. 28:1992;61-66.
6. File S.E. One-trial tolerance to the anxiolytic effects of chlordiazepoxide in the plus-maze. Psychopharmacology (Berlin). 100:1990;281-282.
7. Gage F.H., Chen K.S., Buzsaki G., Armstrong D. Experimental approaches to age-related cognitive impairments. Neurobiol. Aging. 9:1988;645-655.
8. Gagné J., Giguére C., Tocco G., Ohayon M., Thompson R.F., Baudry M., Massicote G. Effect of phosphatidylserine on the binding properties of glutamate receptors in brain sections from adult and neonatal rats. Brain Res. 740:1996;337-345.
9. 1 receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats. Neuroscience. 69:1995;1067-1074.
10. 2 antagonists on radial maze performance in rats. Behav. Neural. Biol. 50:1988;240-245.
11. Mantovani P., Aporti F., Bonetti A.C., Pepeu G. Effects of phosphatidylserine on brain cholinergic mechanisms. Horrocks L. Phospholipids and the nervous system, vol. 1, Metabolism. 1982;165-172 Raven Press, New York.
12. Millan F., Guidolin D., Polato P., Nunzi M.G., Toffano G. Structural changes of basal forebrain cholinergic neurons in the aged rat. Effect of phosphatidylserine administration. Pepeu G., Tomlinson B., Wischik C.M. New trends in aging research. 1988;221-231 Liviana Press, Padova.
13. Nunzi M.G., Milan F., Guidolin D., Zanotti A., Toffano G. Therapeutic properties of phosphatidylserine in the aging brain. Hanin I., Pepeu G. Phospholipids. 1990;213-218 Plenum Press, New York.
14. Orr J.W., Keranen L.M., Newton A.C. Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylgliberol. J. Biol. Chem. 267:1992;15263-15266.
15. Pepeu G., Giovannelli L., Giovannini M.G., Pedata F. Effect of phosphatidylserine on cortical acetylcholine release and calcium in adult and aging rats. Horrocks L.A., Freysz I., Toffano G. Phospholipid research and the nervous system. Biochemical and molecular pharmacology. 1986;265-271 Liviana Press, Padova.
16. Procter A., Lowe S.L., Palmer A.M., Francis P.T., Esiri M.M., Stratmann G.C., Najlerahim A., Patel A.J., Hunt A., Bowen D.M. Topographical distribution of neurochemical changes in Alzheimer's disease. J. Neurol. Sci. 84:1988;125-140.
17. Raiteri M., Marchi M., Maura G., Ferlito M., Fontanta G., Robino G. Selective recovery of neurotransmitter release in aged brain after chronic phosphatidylserine. Freysz L., Hawthorne J.N., Toffano G. Neurochemical aspects of phospholipid metabolism. 1989;219-224 Liviana Press, Padova.
18. Samson J.C. The biological basis of phosphatidylserine pharmacology. Clin. Trials J. 24:1987;1-8.
19. Silva R.H., Bellot R.G., Vital M.A.B.F., Frussa-Filho R. Effects of ganglioside GM1 administration on a new discriminative avoidance test in normal adult mice. Psychopharmacology (Berlin). 129:1997;322-328.
20. Sun A.Y., Sun G.Y. Neurochemical aspects of membrane hypothesis of aging. Meier-Ruge W. Interdisciplinary topics in gerontology, vol. 15. CNS aging and its neuropharmacology:1979;34-53 Krager, Basel.
21. Toffano G., Leon A., Mazzari S., Savoini G., Teolato S., Orlando P. Modification of noradrenergic hypothalamic system in rat injected with phosphatidylserine lipossomes. Life Sci. 23:1978;1093-1102.
22. Ueno E., Kuriyama K. Phospholipids and benzodiazepine recognition sites of brain synaptic membranes. Neuropharmacology. 20:1981;1169-1176.
23. Van Der Zee E.A., Douma B.R.K. Historical review of research on protein kinase C in learning and memory. Prog. Neuropsychopharmacol. Biol. Psychiatry. 21:1997;379-406.
24. Zanotti A., Valzelli L., Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berlin). 99:1989;316-321.
25. Zanotti A., Valzelli L., Toffano G. Reversal of scopolamine-induced amnesia by phosphatidylserine in rats. Psychopharmacology (Berlin). 90:1986;274-275.