Effect of acetylation (O-factor 5) on the polyclonal antibody response to Salmonella typhimurium O-antigen

FEMS Immunology and Medical Microbiology

Volumn 26, Issue 1, 1999, Pages 83-92

  Kim, Myung L ^a   Slauch, James M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Lipopolysaccharide; O Antigen; Polyclonal antibody; Salmonella

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; O ANTIGEN; POLYCLONAL ANTIBODY;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNIZATION; INFECTION PREVENTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

ACETYLATION; ACETYLTRANSFERASES; ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; BACTERIAL PROTEINS; FEMALE; MICE; MICE, INBRED BALB C; MUTATION; O ANTIGENS; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; VACCINATION;

EID: 0032876842     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(99)00126-1     Document Type: Article

References (31)

1. Apter F.M., Michetti P., Winner L.S., Mack J.A., Mekalanos J.J., Neutra M.R. Analysis of the roles of antilipopolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio cholerae and cholera toxin by use of monoclonal IgA antibodies in vivo. Infect. Immun. 61:1993;5279-5285.
2. Colwell D.E., Michalek S.M., Briles D.E., Jirillo E., McGhee J.R. Monoclonal antibodies to Salmonella lipopolysaccharide: anti-O-polysaccharide antibodies protect C3H mice against challenge with virulent Salmonella typhimurium. J. Immunol. 133:1984;950-957.
3. Michetti P., Mahan M.J., Slauch J.M., Mekalanos J.J., Neutra M.R. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium. Infect. Immun. 60:1992;1786-1792.
4. Watson D.C., Robbins J.B., Szu S.C. Protection of mice against Salmonella typhimurium with an O-specific polysaccharide-protein conjugate vaccine. Infect. Immun. 60:1992;4679-4686.
5. Hellerqvist C.G., Linberg B., Svensson S., Holme T., Lindberg A.A. Structural studies on the O-specific side-chains of the cell-wall lipopolysaccharide from Salmonella typhimurium 395 MS. Carbohydr. Res. 8:1968;43-55.
6. Jörbeck H.J.A., Svenson S.B., Lindberg A.A. Immunochemistry of Salmonella O-antigens: specificity of rabbit antibodies against the O-antigen 4 determinant elicited by whole bacteria and O-antigen 4 specific saccharide-protein conjugates. J. Immunol. 123:1979;1379-1381.
7. Svenson S.B., Linberg A.A. Immunochemistry of Salmonella O-antigens: preparation of an octasaccharide-bovine serum albumin immunogen representative of Salmonella serogroup B O-antigen and characterization of the antibody response. J. Immunol. 120:1978;1750-1757.
8. Slauch J.M., Lee A.A., Mahan M.J., Mekalanos J.J. Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: OafA is a member of a family of integral membrane trans-acylases. J. Bacteriol. 178:1996;5904-5909.
9. Slauch J.M., Mahan M.J., Michetti P., Neutra M.R., Mekalanos J.J. Acetylation (O-factor 5) affects the structural and immunological properties of Salmonella typhimurium lipopolysaccharide O antigen. Infect. Immun. 63:1995;437-441.
10. Smith S.M., Stocker B.A.D. Colicinogeny and recombination. Br. Med. Bull. 18:1962;46-51.
11. Mann B.A., Slauch J.M. Transduction of low-copy number plasmids by bacteriophage P22. Genetics. 146:1997;447-456.
12. Silhavy, T.J., Berman, M.L. and Enquist, L.W. (1984) Experiments with Gene Fusions. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Janda J., Work E.A. Colorimetric estimation of lipopolysaccharides. FEBS Lett. 16:1971;343-345.
14. Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., Smith F. Colorimetric method for determination of sugars and related substances. Anal. Chem. 28:1956;350-356.
15. Leinikki P.O., Passila S. Quantitative, semiautomated, enzyme-linked immunosorbent assay for viral antibodies. J. Infect. Dis. 136:1977;294-299.
16. Valtonen V.V., Makela P.H. The effect of lipopolysaccharide modification - antigenic factors 1, 5, 12 2 and 27 - on the virulence of Salmonella strains for mice. J. Gen. Microbiol. 69:1971;107-115.
17. Miller S.I., Kukral A.M., Mekalanos J.J. A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence. Proc. Natl. Acad. Sci. USA. 86:1989;5054-5058.
18. - Salmonella typhimurium vaccines in the murine typhoid model. Immunology. 90:1997;618-625.
19. Metcalf E.S., O'Brien A.D. Characterization of murine antibody response to Salmonella typhimurium by a class-specific solid-phase radioimmunoassay. Infect. Immun. 31:1981;33-41.
20. Reeves P. Role of O-antigen variation in the immune response. Trends Microbiol. 3:1995;381-386.
21. Bock K., Meldal M., Bundle D.R., Iversen T., Pinto B.M., Garegg P.J., Kvanstrom I., Norberg T., Lindberg A.A., Svenson S.B. The conformation of Salmonella O-antigenic oligosaccharides of serogroups A, B, and D1 inferred from 1H- and 13C-nuclear magnetic resonance spectroscopy. Carbohydr. Res. 130:1984;35-53.
22. Cygler M., Rose D.R., Bundle D.R. Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment. Science. 253:1991;442-445.
23. Lindberg A.A., Segall T., Weintraub A., Stocker B.A. Antibody response and protection against challenge in mice vaccinated intraperitoneally with a live aroA O4-O9 hybrid Salmonella dublin strain. Infect. Immun. 61:1993;1211-1221.
24. Kabat E.A. The nature of an antigenic determinant. J. Immunol. 97:1966;1-11.
25. Zinkernagel R.M., Bachmann M.F., Kündig T.M., Oehen S., Pirchet H., Hengartner H. On immunological memory. Annu. Rev. Immunol. 14:1996;333-367.
26. Bock K., Meldal M., Bundle D.R., Iversen T., Garegg P.J., Norberg T., Lindberg A.A., Svenson S.B. The conformation of Salmonella O-antigenic polysaccharide chains of serogroups A, B, and D1 predicted by semi-empirical, hard-sphere (HSEA) calculations. Carbohydr. Res. 130:1984;23-34.
27. Brummell D.A., Sharma V.P., Anand N.N., Bilous D., Dubuc G., Michniewicz J., MacKenzie C.R., Sadowska J., Sigurskjold B.W., Sinnott B. Probing the combining site of an anti-carbohydrate antibody by saturation-mutagenesis: role of the heavy- chain CDR3 residues. Biochemistry. 32:1993;1180-1187.
28. Elkins K., Metcalf E.S. Monoclonal antibodies demonstrate multiple epitopes on the O-antigens of Salmonella typhimurium. J. Immunol. 133:1984;2255-2260.
29. Segall T., Jacobsson S.O., Karlsson K., Lindberg A.A. Mucosal immune responses in calves orally vaccinated with a live auxotrophic aroA Salmonella dublin strain. Zentralbl. Veterinarmed. [B]. 41:1994;305-312.
30. Eisenstein T.K., Sultzer B.M. Immunity to Salmonella infection. Adv. Exp. Med. Biol. 162:1983;261-296.
31. Konadu E., Shiloach J., Bryla D.A., Robbins J.B., Szu S.C. Synthesis, characterization, and immunological properties in mice of conjugates composed of detoxified lipopolysaccharide of Salmonella paratyphi A bound to tetanus toxoid with emphasis on the role of O acetyls. Infect. Immun. 64:1996;2709-2715.