Lipolysis is an important determinant of isoproterenol-induced myocardial necrosis

Cardiovascular Pathology

Volumn 8, Issue 5, 1999, Pages 255-261

  Mohan, Pamarthi ^a   Bloom, Sherman ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ISOPRENALINE; OXFENICINE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; HEART MUSCLE NECROSIS; LIPID ANALYSIS; LIPID METABOLISM; LIPOLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE; ANIMALS; ASCORBIC ACID; CARDIOMYOPATHIES; DRUG SYNERGISM; GLYCEROL; GLYCINE; HEART; ISOPROTERENOL; LIPOLYSIS; LIPOPROTEIN LIPASE; MALE; MYOCARDIUM; NECROSIS; PHOSPHOLIPASES A; PROPRANOLOL; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0032876274     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1054-8807(99)00017-4     Document Type: Article

References (43)

1. Balaz T., Bloom S. Cardiotoxicity of adrenergic bronchodilator and vasodilating antihypertensive drugs. Van Stee Cardiovascular Toxicology. 1982;199-220 Raven Press, New York.
2. Rockhold R.W. Cardiotoxicity of naturally occurring catecholamines. Baskin S.I. Principles of Cardiac Toxicology. 1991;347-417 CRC Press, Boca Raton, FL.
3. Bloom S., Davis D.L. Calcium as mediator of isoproterenol-induced myocardial necrosis. Am J Pathol. 69:1972;459-470.
4. Bloom S., Cancilla P. Myocytolysis and mitochondrial calcification after low doses of isoproterenol. Am J Pathol. 54:1969;373-391.
5. Dhalla K.S., Rupp H., Beamish R.E., Dhalla N.S. Mechanisms of alterations in cardiac membrane calcium transport due to excess catecholamines. Cardiovascular Drugs and Therapy. 10:1996;231-238.
6. Rona G. Catecholamine Cardiotoxicity. J Mol Cell Cardiol. 17:1985;291-306.
7. Mraz M., Kren V., Krsiakova D., Vrana A., Hynie S. The role of myocardial glycogen content for the development of isoprenaline-induced myocardial lesions in different inbred strains of rats. Basic Res Cardiol. 90:1995;467-474.
8. Scheuer J., Stezoski W.A.S. Protective role of increased myocardial glycogen stores in cardiac anoxia in the rat. Circ Res. 27:1970;835-849.
9. Brembilla-Perrot B., Chaise T.D.L., Le V.D., Beurrier D. Effect of isoproterenol on serum and potassium and magnesium. Eur Heart J. 14:1993;677-681.
10. Singal P.K., Dhillon K.S., Beamish R.E., Dhalla N.S. Protective effect of zinc against catecholamine-induced myocardial changes. Lab Invest. 44:1981;426-433.
11. Ferrans V.J., Hibbs R.G., Walsh J.J., Burch G.E. Histochemical and electron microscopical studies on the cardiac necrosis produced by sympathomimetic agents. Ann NY Acad Sci. 156:1969;309-332.
12. Joseph X., Balaz T. Protection against isoproterenol-induced myocardial necrosis in rat by 6-mercaptopurine and -thioguanine or by irradiation. Res Commun Chem Pathol Pharmacol. 63:1989;385-394.
13. Persoon-Rothert M., Van Der Valk-Kokshoorn E.J., Egas-Kenniphaas J.M., Mauve I., Van Der Laarse A. Isoproterenol-induced cytotoxicity in neonatal rat heart cell cultures is mediated by free radical formation. J Mol Cell Cardiol. 21:1989;1285-1291.
14. Singal P.K., Dhillon K.S., Beamish R.E., Dhalla N.S. Role of free radical in catecholamine-induced cardiomyopathy. Can J Pharmacol. 60:1981;1390-1397.
15. Garcia-Sainz J.A., Fain J.N. Regulation of adipose tissue metabolism by catecholamines. roles of alpha-1, alpha-2 and beta-adrenoceptors Trends Pharmacol Sci. 3:1982;201-203.
16. Palmer W.K., Kane T.A. Hormone-stimulated lipolysis in cardiac myocytes. Biochem J. 216:1983;241-243.
17. Schwartz D.D., Williams J.L., Malik K.U. Contribution of calcium to isoproterenol stimulated lipolysis in the isolated perfused rabbit heart. Am J Physiol. 28:1993;E439-E445.
18. Brownsey R.W., Brundt R.V. The effect of adrenalin-induced endogenous lipolysis upon the mechanical and metabolic performance of ischemically perfused rat hearts. Clin Sci Mol Med. 53:1977;513-521.
19. Buja M.L. Lipid abnormalities in myocardial cell injury. Trends Cardiovasc Med. 1:1991;40-45.
20. Dhalla N.S., Elimban V., Rupp H. Paradoxical role of lipid metabolism in heart function and dysfunction. Mol Cell Biochem. 116:1992;3-9.
21. Shug A.L., Shrago E. A proposed mechanism for fatty acid effects on energy metabolism of the heart. J Lab Clin Med. 81:1973;214-218.
22. Balaz T., Sahashrabudhe M.R., Grice H.C. The influence of excess body fat on the cardiotoxicity of isoproterenol in rats. Toxicol Appl Pharmacol. 4:1962;613-620.
23. Mohan P.F., Bloom S. Food restriction protects and obesity increases isoproterenol induced myocardial necrosis. Cardiovasc Pathol. 6:1997;287-291.
24. Zavier J., Bloom S., Pledger G., Balazs T. Determinants of resistance to the cardiotoxicity of isoproterenol in rats. Toxicol Appl Pharmacol. 69:1983;199-205.
25. Eggstein M., Kuhlmann E. Triglycerides and glycerol determination after alkaline hydrolysis. Bergmeyer H.U. Methods in Enzymatic Analysis, Vol. 4. 1974;1825-1835 Academic Press, New York.
26. Carey G.B., Sidmore K.A. Exercise attenuates the anti-lipolytic effects of adenosine in adipocytes isolated from miniature swine. Int J Obesity & Related Metabol Disorder. 18:1994;2155-2160.
27. Schwartz G.G., Greyson C., Wisneski J.A., Garcia J. Inhibition of fatty acid metabolism alters myocardial high-energy phosphates in vivo. Am J Physiol. 36:1994;H224-H231.
28. Beyer R.E. The role of ascorbate in antioxidant protection of biomembranes. Interaction with vitamin E and Coenzyme Q.J Bioenergetics and Biomembranes. 26:1994;349-358.
29. Glantz S.A. The special case of two groups. The t-test Primer of Biostatistics. 1992;67-109 McGraw-Hill, Inc, New York.
30. Vik-Mo H., Mjos O.D. Influence of free fatty acids on myocardial oxygen consumption and ischemic injury. Am J Cardiol. 48:1981;361-365.
31. Higuchi Y. Changes of lipid peroxides and α-tocopherol in rats with experimental induced myocardial necrosis. Acta Med Okayama. 36:1982;113-124.
32. Namikawa K., Okazaki Y., Nishida S., Kadota E., Tomura T., Hashimoto S. Studies on early stage changes of peroxide lipid in isoproterenol-induced myocardial injury. Yakugaku Zasshi. 112:1992;557-562.
33. Cao G., Giovanoni M., Prior R.L. Anti-oxidant capacity of different tissues of young and old rats. PSEBM. 211:1996;359-365.
34. Krame J.H., Mak I.T., Weglicki W.B. Differential sensitivity of canine cardiac sarcolemmal and microsomal enzymes to inhibition by free radical-induced lipid peroxidation. Circ Res. 55:1984;120-124.
35. Yates J.C., Beamish R.E., Dhalla N.S. Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine. Relation to pathogenesis of catecholamine cardiomyopathy Am Heart J. 102:1981;210-221.
36. Jones R.L., Miller J.C., Hagler H.K., Chien K.R., Willerson J.T., Buja L.M. Association between inhibition of arachidonic acid release and prevention of calcium loading during ATP depletion in cultured rat cardiac myocytes. Am J Pathol. 135:1989;541-546.
37. Freedman A.M., Kramer J.H., Mak T., Cassidy M.M., Weglicki W.B. Propranolol preserves ultrastructure in adult cardiocytes exposed to anoxia/reoxygenation. A morphometric analysis Free Radical Biol Med. 11:1991;197-206.
38. Jenkins R.R., Singore D.C.M., Sauer P., Skelly C. The effect of beta blocking drugs on lipid peroxidation in rat heart in vitro. Lipids. 27:1992;539-542.
39. Marchetti G., Merlo L., Noseda V. Myocardial uptake of free fatty acids and carbohydrates after beta adrenergic blockade. Am J Cardiol. 22:1968;370-374.
40. Opie L.H., Thomas M. Propranolol and experimental myocardial infarction. Substrate effects Postgraduate Medical Journal. Suppl 4):1976;124-133.
41. Mueller H.S., Ayres S.M., Religa A., Evans R.G. Propranolol in the treatment of acute myocardial infarction. Effect on myocardial oxygenation and hemodynamics Circulation. 49:1974;1078-1087.
42. Steigen T.K., Myrmel T., Forsdahl K., Larsen T.S. Myocardial cell vulnerability to exogenous phospholipase attack. Mol Cell Biochem. 116:1992;47-52.
43. Katz A.M., Messineo F.C. Lipid-Membrane interactions and the pathogenesis of ischemic damage in the myocardium. Circ Res. 48:1981;1-16.