Inhibitory effects from various types of dorsal column and raphe magnus stimulations on nociceptive withdrawal flexion reflexes

Brain Research

Volumn 846, Issue 1, 1999, Pages 72-86

  Saadé, Nayef E ^a   Atweh, Samir F ^a   Privat, Alain ^b   Jabbur, Suhayl J ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b INSERM   (France)

Author keywords

Brainstem; Dorsal column; Electroanalgesia; Flexion reflexes; Pain modulation; Raphe

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; CAT; CONTROLLED STUDY; DECEREBRATION; ELECTROANALGESIA; ELECTROSTIMULATION; FLEXOR REFLEX; MALE; MOTONEURON; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAPHE MAGNUS NUCLEUS; REFLEX; SPINAL CORD DORSAL HORN; SPINE; VENTRAL ROOT;

ACTION POTENTIALS; ANIMALS; CATS; CONDITIONING (PSYCHOLOGY); MALE; MOTOR NEURONS; NERVE FIBERS; NEURAL INHIBITION; NOCICEPTORS; PAIN; RAPHE NUCLEI; REFLEX; SPINAL CORD; TRANSCUTANEOUS ELECTRIC NERVE STIMULATION;

EID: 0032875794     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02003-X     Document Type: Article

References (70)

1. Bantli H., Bloedel J.R., Long D.M., Thienprasit P. Distribution of activity in spinal pathways evoked by experimental dorsal column stimulation. J. Neurosurg. 42:1975;290-295.
2. Bantli H., Bloedel J.R., Thienprasit P. Supraspinal interactions resulting from experimental dorsal column stimulation. J. Neurosurg. 42:1975;296-300.
3. Berkley K.J., Budell R.J., Blomquist A., Bull M. Output systems of the dorsal column nuclei in the cat. Brain Res. Rev. 11:1986;199-225.
4. A.L. Berman, The Brain Stem of the Cat, University of Wisconsin Press, Madison, 1968.
5. J.-M.R. Besson, Supraspinal modulation of the segmental transmission of pain, in: H.W. Kosterlitz, L.Y. Terenius (Eds.), Pain and Society, Dahlem Konferenzen 1980, Verlag Chemie, Weinheim, pp. 161-182.
6. Brown A.G., Martin H.F. III Activation of descending control of the spinocervical tract by impulses ascending the dorsal columns and relaying through the dorsal column nuclei. J. Physiol. 235:1973;535-550.
7. Burke R.E., Rudomin P., Vyklicky L., Zajac III F.E. Primary afferent depolarization and flexion reflexes produced by radiant heat stimulation of the skin. J. Physiol. 213:1971;185-214.
8. Campbell I.G., Carstens E., Watkins L.R. Comparison of human pain sensation and flexion withdrawal evoked by noxious radiant heat. Pain. 45:1991;259-268.
9. Campbell J.N. Examination of possible mechanisms by which stimulation of the spinal cord in man relieves pain. Appl. Neurophysiol. 44:1981;181-186.
10. Chung J.M., Fang Z.R., Cargill C.L., Willis W.D. Prolonged, naloxone-reversible inhibition of the flexion reflex in the cat. Pain. 15:1983;35-53.
11. Dougherty M., Shea S., Liu C.N., Chambers W.W. Effects of spinal cord lesions on cutaneously elicited reflexes in the decerebrate cat. Tonic bulbospinal and spinobulbar inhibitory systems. Exp. Neurol. 26:1970;551-570.
12. Eliasson T., Augutinsson L.E., Mannheimer C. Spinal cord stimulation in severe angina pectoris - presentation of current studies, indications and clinical experience. Pain. 65:1996;169-179.
13. Fields H.L., Anderson S.D. Evidence that raphe-spinal neurons mediate opiate and midbrain stimulation-produced analgesia. Pain. 5:1978;333-349.
14. Fields H.L., Basbaum A.I. Brainstem controls of spinal pain-transmission neurons. Annu. Rev. Physiol. 40:1978;217-248.
15. Foreman R.D., Beall J.E., Applebaum A.E., Coulter J.D., Willis W.D. Effects of dorsal column stimulation on primate spinothalamic tract neurons. J. Neurophysiol. 39:1976;534-546.
16. Garcia-Larrea L., Sindou M., Mauguiere F. Nociceptive flexion reflexes during analgesic neurostimulation in man. Pain. 39:1989;145-156.
17. Gildenberg P.L. Treatment of spasmodic torticollis by dorsal column stimulation. Appl. Neurol. 41:1978;113-121.
18. Gybels J.M., Kupers R. Central and peripheral electrical stimulation of the nervous system in the treatment of chronic pain. Acta Neurochir. Suppl. 38:1987;64-75.
19. Hagbarth K.E. Excitatory and inhibitory skin areas for flexor and extensor motorneurones. Acta Physiol. Scand. 26:1952;1-58. Suppl. 94.
20. Handwerker H.O., Iggo A., Zimmermann M. Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli. Pain. 1:1975;147-165.
21. Holmqvist B., Lundberg A. Differential supraspinal control of synaptic actions evoked by volleys in the flexion reflex afferents in alpha motorneurones. Acta Physiol. Scand. 54:1961;1-51. Suppl. 186.
22. Hoppenstein R. Electrical stimulation of the ventral and dorsal columns of the spinal cord for relief of chronic intractable pain: Preliminary report. Surg. Neurol. 4:1975;187-194.
23. Hosobuchi Y., Adams J.E., Weinstein P.R. Preliminary percutaneous dorsal column stimulation prior to permanent implantation. J. Neurosurg. 37:1972;242-245.
24. Hunter J.P., Ashby P. Segmental effects of epidural spinal cord stimulation in humans. J. Physiol. 474:1994;407-449.
25. Illis L.S., Sedgwick E.H., Oygar A.E., Awadalla M.A. Dorsal column stimulation in the rehabilitation of patients with multiple sclerosis. Lancet. 26:1970;1383-1385.
26. Iwamoto G.A., Ryu H., Wagman I.H. Contribution of unmyelinated afferents from the sural nerve to spinal reflex activity. Exp. Neurol. 62:1978;260-267.
27. S.J. Jabbur, N.E. Saadé, N.R. Banna, Excitatory and inhibitory interactions between dorsal and ventral column inputs into the cat postcruciate cortex, in: E. Grastyan, P. Molnar (Eds.), Adv. Physiol. Sci., Vol. 16, Sensory Functions, Pergamon, Budapest, 1981, pp. 171-180.
28. Jabbur S.J., Saadé N.E., Atweh S.F. Dorsal column (DC) input into periaqueductal gray (PAG) in decerebrate decerebellate cats. Society for Neuroscience (USA). 10:1984;101. Abstracts.
29. S.J. Jabbur, N.E. Saadé, Interactions between dorsal column and ventral spinal inputs in somatosensory thalamocortical areas and in various brainstem nuclei in the cat, in: M.M. Rowe, W.D. Willis, Jr. (Eds.), Development, Organization, and Processing in Somatosensory Pathways, Neurology and Neurobiology, Vol. 14, Alan R. Liss, New York, 1985, pp. 223-229.
30. F.U. Krainick, U. Thoden, Spinal cord stimulation, in: P.D. Wall, R. Melzack (Eds.), Textbook of Pain, Churchill Livingston, London, 1989, pp. 920-924.
31. Larson S.J., Sances A., Cusick J.F., Meyer G.A., Swiontek T. A comparison between anterior and posterior spinal implant systems. Surg. Neurol. 4:1975;180-186.
32. Larson S.J., Sances A. Jr., Riegel D.H., Meyer G.A., Dallmann D.E., Swiontek T. Neurophysiological effects of dorsal column stimulation in man and monkey. J. Neurosurg. 41:1974;217-223.
33. Light A.R., Casale E.J., Menétrey D.M. The effects of focal stimulation in nucleus raphe magnus and periaqueductal gray on intracellularly recorded neurons in spinal laminae I and II. J. Neurophysiol. 56:1986;555-571.
34. Lindblom U., Meyerson B.A. Influence on touch, vibration and cutaneous pain of dorsal column stimulation in man. Pain. 1:1975;257-270.
35. Lindblom U., Tapper D.N., Wiesenfeld Z. The effect of dorsal column stimulation on the nociceptive response of dorsal horn cells and its relevance for pain suppression. Pain. 4:1977;133-144.
36. Linderoth B., Meyerson B.A. Dorsal column stimulation: modulation of somatosensory and autonomic function. The Neurosciences. 7:1995;263-277.
37. Marchand S., Bushnell M.C., Molina-Negro P., Martinez S.N., Duncan G.H. The effects of dorsal column stimulation on measures of clinical and experimental pain in man. Pain. 45:1991;249-257.
38. Meglio M., Cioni B., D'amico E., Ronzoni G., Rossi G.F. Epidural spinal cord stimulation for the treatment of neurogenic bladder. Acta Neurochir. 54:1980;191-199.
39. Meglio M., Cioni B., Rossi G.F., Sandric S., Santarelli P. Spinal cord stimulation affects the central mechanisms of regulation of heart rate. Appl. Neurophysiol. 49:1986;139-146.
40. Melzack R., Wall P.D. Pain mechanisms: a new theory. Science. 150:1965;971-979.
41. B.A. Meyerson, Electric stimulation of the spinal cord and brain, in: J.J. Bonica (Ed.), The Management of Pain, Lea and Febiger, Philadelphia, 1990, pp. 1862-1877.
42. Meyerson B.A., Ren B., Herregodts P., Linderoth B. Spinal cord stimulation in animal models of mononeuropathy: effects on the withdrawal response and the flexor reflex. Pain. 61:1995;229-243.
43. Nashold B.S. Jr., Friedman H. Dorsal column stimulation for control of pain. Preliminary report on 30 patients. J. Neurosurg. 36:1972;590-597.
44. Nashold B. Jr., Somjen G., Friedman H. Paresthesias and EEG potentials evoked by stimulation of the dorsal funiculi in man. Exp. Neurol. 36:1972;273-287.
45. Nyquist J.K., Greenhoot J.H. Responses evoked from the thalamic centrum medianum by painful input: suppression by dorsal funiculus conditioning. Exp. Neurol. 39:1973;215-222.
46. Price D.D. Characteristics of second pain and flexion reflexes indicative of prolonged central summation. Exp. Neurol. 37:1972;371-387.
47. Rees H., Roberts M.H.T. Antinociceptive effects of dorsal column stimulation in the rat: involvement of the anterior pretectal nucleus. J. Physiol. 417:1989;375-388.
48. Ren B., Linderoth B., Meyerson B.A. Effects of spinal cord stimulation on the flexor reflex and involvement of supraspinal mechanisms: An experimental study in mononeuropathic rats. J. Neurosurg. 84:1996;244-249.
49. Saadé N.E., Jabbur S.J., Banna N.R. Interactions of isolated dorsal column and ventral spinal ascending volleys on single neurons in the post-cruciate cortex (SmI) of the cat. Brain Res. 201:1980;446-451.
50. Saadé N.E., Atweh S.F., Tabet M.S., Jabbur S.J. Inhibition of nociceptive withdrawal flexion reflexes through a dorsal column-brainstem-spinal loop. Brain Res. 335:1985;306-308.
51. Saadé N.E., Jundi A.S., Jabbur S.J., Banna N.R. Dorsal column input to inferior raphe centralis neurons. Brain Res. 250:1982;345-348.
52. Saadé N.E., Salibi N.A., Banna N.R., Towe A.L., Jabbur S.J. Spinal input pathways affecting the medullary gigantocellular reticular nucleus. Exp. Neurol. 80:1983;582-600.
53. Saadé N.E., Tabet M.S., Banna N.R., Atweh S.F., Jabbur S.J. Inhibition of nociceptive evoked activity in spinal neurons through a dorsal column-brainstem-spinal loop. Brain Res. 339:1985;115-118.
54. Saadé N.E., Tabet M.S., Souiedan S.A., Bitar M., Atweh S.F., Jabbur S.J. Supraspinal modulation of nociception in awake rats by stimulation of the dorsal column nuclei. Brain Res. 369:1986;307-310.
55. Saadé N.E., Atweh S.F., Jabbur S.J. Descending inhibitory pathways from the brainstem modulating the late reflex discharge (LRD) evoked by C-fiber afferent volleys. Pain. Suppl. 5:1993;S269.
56. Salibi N.A., Saadé N.E., Banna N.R., Jabbur S.J. Dorsal column input into the reticular formation. Nature. 288:1980;481-483.
57. Schomburg E.D., Steffens H. Synaptic responses of lumbar α-motorneurones to selective stimulation of cutaneous nociceptors and low threshold mechanoreceptors in the spinal cat. Exp. Brain Res. 62:1986;335-342.
58. Schouenborg J., Sjolund B.H. Activity evoked by A- and C-afferent fibers in rat dorsal horn neurons and its relation to a flexion reflex. J. Neurophysiol. 50:1983;1108-1121.
59. Shealy C.N., Mortimer J.T., Reswick J.B. Electrical inhibition of pain by stimulation of the dorsal columns. Anesth. Analg. 46:1967;489-491.
60. Shetter A.G., Atkinson J.R. Dorsal column stimulation: its effect on medial bulboreticular unit activity evoked by noxious stimuli. Exp. Neurol. 54:1977;185-198.
61. Siegfried J., Krainick J.U., Haas H., Adorjani C., Meyer M., Thoden U. Electrical spinal cord stimulation for spastic movement disorders. Appl. Neurophysiol. 41:1978;134-141.
62. Sweet W.H., Wepsic J.G. Stimulation of the posterior columns of the spinal cord for pain control: indications, technique, and results. Clin. Neurol. Neurosurg. 21:1974;278-310.
63. Tallis R.C., Illis L.S., Sedgwick E.M., Hardwidge C., Garfield J.S. Spinal cord stimulation in peripheral vascular disease. J. Neurol. Neurosurg. Psychiat. 43:1983;478-484.
64. Thoden U., Krainick J.U., Straburg H.M., Wenzel D. Modulation of monosynaptic reflexes by dorsal column stimulation (DCS) in spasticity. Pflugers Arch. Gesamte Physiol. Menschen Tiere. 365:1976;R41.
65. Wall P.D., Sweet W.H. Temporary abolition of pain in man. Science. 155:1967;108-109.
66. West D.C., Wolstencroft J.H. Strength-duration characteristics of myelinated and non-myelinated bulbospinal axons in the cat spinal cord. J. Physiol. 377:1983;37-50.
67. West D.C., Wolstencroft J.H. Location and conduction velocity of raphe spinal neurones in nucleus raphe magnus and raphe pallidus in the cat. Neurosci. Lett. 5:1977;147-151.
68. Willer J.C. Comparative study of perceived pain and nociceptive flexion reflex in man. Pain. 3:1977;69-80.
69. Willis W.D. The raphe-spinal system. Brainstem control of spinal cord function. Res. Top. Physiol. 6:1984;141-214.
70. Woolf C.J., Swett J.E. The cutaneous contribution to the hamstring flexor reflex in the rat: an electrophysiological and anatomical study. Brain Res. 303:1984;299-312.