Role of nitric oxide in intrarenal hemodynamics in experimental diabetes mellitus in rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 277, Issue 3 46-3, 1999, Pages

  Pflueger, Axel C ^a   Larson, Timothy S ^a   Hagl, Siegfried ^b   Knox, Franklyn G ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Diabetic endothelial dysfunction; Experimental insulin dependent diabetes mellitus; N(G) monomethyl L arginine; Nitric oxide dependent renal vasodilation; Videomicroscopy

Indexed keywords

ARGININE; N(G) METHYLARGININE; NITRIC OXIDE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; KIDNEY BLOOD FLOW; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; URINARY EXCRETION; VASODILATATION;

EID: 0032875130     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.277.3.r725     Document Type: Article

References (36)

1. Ashraf, S., N. Shaukat, I. Kamaly, A. Durrani, B. Doran, G. Grotte, and D. Keenan. Determinants of early and late mortality in patients with end-stage renal disease undergoing cardiac surgery. Scand. J. Thorac. Cardiovasc. Surg. 29: 187-193, 1995.
2. Bachman, S. Distribution of NOSs in the kidney. In: Nitric Oxide and the Kidney, edited by M. Gologorsky and S. Gross. New York: Chapman & Hall, 1997, p. 349-367.
3. Bank, N., and H. Aynedjian. Role of EDRF (nitric oxide) in diabetic hyperfiltration. Kidney Int. 43: 1306-1312, 1993.
4. Bucala, R., and H. Vlassara. Advanced glycosylation end products in diabetic renal and vascular disease. Am. J. Kidney Dis. 26: 875-888, 1995.
5. Carmines, P. K., K. Ohishi, and H. Ikenaga. Functional impairment of renal afferent arteriolar voltage-gated calcium channels in rats with diabetes mellitus. J. Clin. Invest. 98: 2564-2571, 1996.
6. Chou, S., J. Porush, and P. Faubert. Renal medullary circulation: hormonal control. Kidney Int. 37: 1-13, 1990.
7. Cohen, R. Dysfunction of vascular endothelium in diabetes mellitus. Circulation 87, Suppl.: V67-V76, 1993.
8. Cosentino, F., K. Hishikawa, Z. Katusic, and T. Luescher. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25-28, 1997.
9. Craven, P. A., R. K. Studer, and F. R. Derubertis. Impaired nitric-oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. J. Clin. Invest. 93: 311-320, 1994.
10. Dai, R. X., A. Diederich, J. Skopec, and D. Diederich. Diabetes-induced dysfunction in streptozotocin-treated rats: role of prostaglandin endoperoxides and free radicals. J. Am. Soc. Nephrol. 4: 1327-1336, 1993.
11. Diederich, D. Nitric oxide in diabetic nephropathy. In: Nitric Oxide and the Kidney, edited by M. S. Gologorsky and S. S. Gross. New York: Chapman & Hall, 1997, p. 349-367.
12. Fuehr, J., J. Kaczmarczyk, and C. Kruettgen. Eine einfache colorimetrische Methode zur Inulinbestimmung fuer Nieren Clearance Untersuchungen bei Stoffwechselgesunden und Diabetikern. Klin. Wochenschr. 33: 729-730, 1955.
13. Griffin, M., E. Bergstralhn, and T. Larson. Renal papillary necrosis - a sixteen year clinical experience. J. Am. Soc. Nephrol. 6: 248-256, 1995.
14. Gussis, G., R. Jamison, and C. Robertson. Determination of erythrocyte velocities in the mammalian inner renal medulla by a video velocity-tracking system. Microvasc. Res. 18: 370-383, 1979.
15. Holliger, C., K. Lemley, S. Schmitt, F. Thomas, and C. Robertson. Direct determination of vasa recta blood flow in the rat papilla. Circ. Res. 53: 401-413, 1983.
16. Hostetter, T. H., J. L. Troy, and B. M. Brenner. Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int. 19: 410-415, 1981.
17. Hoult, J. R. S., and P. K. Moore. Prostaglandin synthesis and inactivation in kidneys and lungs of rats with experimental diabetes. Clin. Sci. (Colch.) 59: 63-66, 1980.
18. Ikeda, U., K. Yamamoto, Y. Maida, M. Shimpo, T. Kanbe, and K. Shimada. Endothelin-1 inhibits nitric oxide synthesis in vascular smooth muscle cells. Hypertension 29: 65-69, 1997.
19. Komers, R., T. J. Allen, and M. E. Cooper. Role of endothelium-derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes. Diabetes 43: 1190-1197, 1994.
20. G-monomethyl-L-arginine. Circ. Res. 75: 829-835, 1994.
21. Ohishi, K., P. Carmines, W. Inscho, and L. Navar. EDRF-angiotensin II interactions in rat juxtamedullary afferent and efferent arterioles. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F900-F906, 1992.
22. Ohishi, K., and P. K. Carmines. Superoxide dismutase restores the influence of nitric oxide on renal arterioles in diabetes mellitus. J. Am. Soc. Nephrol. 5: 1559-1566, 1995.
23. Park, F., D. Mattson, L. Roberts, and J. A. Cowley. Evidence for the presence of smooth muscle α-actin within pericytes of the renal medulla. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R1742-R1748, 1997.
24. Pflueger, A. C., T. S. Larson, S. Hagl, S. M. Sandberg, J. C. Burnett, Jr., and F. G. Knox. Cyclic GMP-dependent renal vasodilation is uncoupled from nitric oxide in diabetic rats (Abstract). J. Am. Soc. Nephrol. 9: 356A-357A, 1998.
25. Pflueger, A. C., H. Osswald, and F. G. Knox. Adenosine-induced renal vasoconstriction in diabetes mellitus rats: role of nitric oxide. Am. J. Physiol. 276 (Renal Physiol. 45): F340-F346, 1999.
26. Pflueger, A. C., F. Schenk, and H. Osswald. Increased sensitivity of the diabetic renal vasculature to adenosine in streptozotocin-induced diabetes mellitus rats. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F529-F535, 1995.
27. Rudnick, M. R., S. Goldfarb, L. Wexler, A. Ludbrook, M. J. Murphy, E. F. Halpern, J. A. Hill, M. Winnford, M. B. Cohen, and D. B. VanFossen. Nephrotoxicity of ionic contrast media in 1196 patients: a randomized trial. Kidney Int. 47: 254-261, 1995.
28. Shafrir, E. Diabetes in animals. In: Ellenberg & Rifkins's Diabetes Mellitus (5th Ed.), edited by J. Porte, and R. S. Sherwin. New York: Appleton & Lang, 1997, p. 301-348.
29. Tesfamariam, B., M. L. Brown, and R. A. Cohen. Elevated glucose endothelium-dependent relaxation by activating protein kinase C. J. Clin. Invest. 87: 1643-1648, 1991.
30. Tolins, J. P., P. J. Schultz, L. Raij, D. M. Brown, and S. M. Mauer. Abnormal renal hemodynamic response to reduced renal perfusion pressure in diabetic rats: role of NO. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F886-F895, 1993.
31. Walder, C., C. Thiemermann, and J. Vane. The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat. Br. J. Pharmacol. 102: 967-973, 1991.
32. Wang, Y. X., D. P. Brooks, and R. M. Edward. Attenuated glomerular cGMP production and renal vasodilation in streptozotocin-induced diabetic rats. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R952-R956, 1993.
33. Yang, S., E. Silldorff, and T. Pallone. Effect of norepinephrine and acetylcholine on outer medullary descending vasa recta. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H710-H716, 1995.
34. Zatz, R., and G. de Nucci. Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F360-F363, 1991.
35. Zimmerhackl, B., J. Tinsman, R. Jamison, and C. Robertson. Use of digital cross-correlation for on-line determination of single-vessel blood flow in the mammalian kidney. Microvasc. Res. 30: 63-74, 1985.
36. Zou, A., and J. A. Cowley. Nitric oxide in renal cortex and medulla - an in vivo microdialysis study. Hypertension 29: 194-198, 1997.