Pulmonary rapidly adapting receptor stimulation does not increase airway resistance in anesthetized rabbits

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 3, 1999, Pages 906-912

  Yu, Jerry ^a   Zhang, Ju F ^a   Roberts, Andrew M ^a   Collins, Lynell C ^a   Fletcher, Eugene C ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; SUXAMETHONIUM;

AIRFLOW; AIRWAY PRESSURE; AIRWAY RESISTANCE; ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; BRONCHOSPASM; CONTROLLED STUDY; COUGHING; LUNG COMPLIANCE; LUNG RECEPTOR; LUNG RESISTANCE; MALE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; TIDAL VOLUME; VAGUS NERVE STIMULATION;

EID: 0032874890     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.3.9809085     Document Type: Article

References (31)

1. Knowlton, G. C., and M. G. Larrabee. 1946. A unitary analysis of pulmonary volume receptors. Am. J. Physiol. 147:100-114.
2. Coleridge, H. M., and J. C. G. Coleridge. 1994. Pulmonary reflexes: neural mechanisms of pulmonary defense. Annu. Rev. Physiol. 56:69-91.
3. Coleridge, H. M., J. C. G. Coleridge, and H. D. Schultz. 1089. Afferent pathways involved in reflex regulation of airway smooth muscle. Pharmacol. Ther. 42:1-63.
4. Sant'Ambrogio, G. 1982. Information arising from the tracheobronchial tree of mammals. Physiol. Rev. 62:531-569.
5. Selliek, H., and J. G. Widdicombe. 1969. The activity of lung irritant receptors during pneumothorax, hyperpnoea and pulmonary vascular congestion. J. Physiol. (Lond.) 203:350-381.
6. Selliek, H., and J. G. Widdicombe. 1971. Stimulation of lung irritant receptors by cigarette smoke, carbon dust, and histamine aerosol. J. Appl. Physiol. 31:15-19.
7. Vidruk, E. H., H. L. Hahn, J. A. Nadel, and S. R. Sampson. 1977. Mechanisms by which histamine stimulates rapidly adapting receptors in dogs lungs. J. Appl Physiol. 43:397-402.
8. Karlsson, J. A., G. Sant'Ambrogio, and J. Widdicombe. 1988. Afferent neural pathways in cough and reflex bronchoconstriction. J. Appl. Physiol. 65:1007-1023.
9. Sant'Ambrogio, G. 1987. Afferent nerves in reflex bronchoconstriction. Bull. Eur. Physiopathol. Reapir. 23:81s-88s.
10. Widdicombe, J. G. 1995. Neurophysiology of the cough reflex. Eur. Respir. J. 8: 1193-1202.
11. Paintal, A. S. 1977. The nature and effects of sensory inputs into the respiratory centers. Fed. Proc. 36:2428-2432.
12. Pack, A. I. 1981. Sensory inputs to the medulla. Annu. Rev. Physiol. 43: 73-90.
13. Coleridge, H. M., and J. C. G. Coleridge. 1986. Reflexes evoked from tracheobronchial tree and lungs. In N. S. Cherniack and J. G. Widdicombe, editors. Handbook of Physiology. Section 3: The Respiratory System, Vol. II: Control of breathing, part 1, American Physiological Society, Bethesda, MD. 395-429.
14. Yu, J., and S. Mink. 1996. Activation of pulmonary rapidly adapting receptors does not induce bronchoconstriction in dogs. J. Appl. Physiol. 80:233-239.
15. Widdicombe, J. G. 1986. Role of the parasympathetic cholinergic system in normal and obstructed airway. Respiration 50(S2):1-8.
16. Amdur, M. O., and J. Mead. 1958. Mechanics of respiration in unanesthetized guinea-pigs. Am. J. Physiol. 192:364-368.
17. Yu, J., H. Schultz, J. Goodman, J. C. G. Coleridge, H. M. Coleridge, and B. Davis. 1989. Pulmonary rapidly adapting receptors reflexly increase airway secretion in dogs. J. Appl. Physiol. 67:682-687.
18. Yu, J., and A. M. Roberts. 1990. Indirect effects of histamine on pulmonary rapidly adapting receptors in cats. Respir. Physiol. 79:101-110.
19. Leff, A. R., N. M. Munoz, and B. Alderman. 1982. Measurement of airway response by isometric and nonisometric techniques in situ. J. Appl. Physiol. 52:1363-1367.
20. Yu, J., J. C. G. Coleridge, and H. M. Coleridge. 1987. Influence of lung stiffness on rapidly adapting receptors in rabbits and cats. Respir. Physiol. 68:161-176.
21. Pisarri, T. E., A. Jonzon, H. M. Coleridge, and J. C. G. Coleridge. 1992. Vagal afferent and reflex responses to changes in surface osmolarity in lower airways of dogs. J. Appl. Physiol. 73:2305-2313.
22. Kappagoda, C. T., G. C. W. Man, K. Ravi, and K. K. Teo. 1988. Reflex tracheal contraction during pulmonary venous congestion in the dog. J. Physiol. (Lund.) 402:335-346.
23. Roberts, A. M., J. Bhattacharya, H. D. Schultz, H. M. Coleridge, and J. C. G. Coleridge. 1986. Stimulation of vagal afferent C-fibers by lung edema in dogs. Circ: Res. 58:512-522.
24. Jonzon, A., T. E. Pisarri, A. M. Roberts, J. C. G. Coleridge, and H. M. Coleridge. 1988. Attenuation of naturally-evoked activity in pulmonary afferent fibers by vagal cooling. Respir. Physiol. 72:19-34.
25. Tatar, M., G. Sant'Ambrogio, and T. B. Sant'Ambrogio. 1994. Laryngeal and trachealbronchial cough in anesthetized dogs. J. Appl. Physiol. 76:2672-2679.
26. Mitchell, G. S., and E. H. Vidruk. 1985. Neural and humeral factors in control of tracheal caliber. J. Appl. Physiol. 59:198-204.
27. Widdicombe, J. G., and J. A. Nadel. 1963. Reflex effects of lung inflation on tracheal volume. J. Appl. Physiol. 18:681-686.
28. 1 but not the cough induced by hypotonie mist. Thorax 39:766-770.
29. Sheppard, D., N. W. Rizk, H. A. Boushey, and R. A. Bethel. 1983. Mechanism of cough and bronchoconstriction induced by distilled water aerosol. Am. Rev. Respir. Dis. 127:691-694.
30. Karczewski, W., and J. G. Widdicombe. 1969. The role of the vagus nerves in the respiratory and circulatory responses to intravenous histamine and phenyl diguanide in rabbits. J. Physiol. (Lond) 201:271-291.
31. Lee, B.-P., G. Sant'Ambrogio, and F. B. Sant'Ambrogio. 1992. Afferent innervation and receptors of the canine extrathoracic trachea. Respir. Physiol. 90:55-65.