-
2
-
-
0016764493
-
A controlled trial of azathioprine in Crohn's disease
-
JL Rosenberg B Levin AJ Wall JB Kirsner A controlled trial of azathioprine in Crohn's disease Dig Dis 20 1975 721 726
-
(1975)
Dig Dis
, vol.20
, pp. 721-726
-
-
Rosenberg, JL1
Levin, B2
Wall, AJ3
Kirsner, JB4
-
3
-
-
0018117298
-
Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease
-
DP O'Donoghue AM Dawson J Powell-Tuck RL Brown JE Lennard-Jones Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease Lancet 2 1978 955 957
-
(1978)
Lancet
, vol.2
, pp. 955-957
-
-
O'Donoghue, DP1
Dawson, AM2
Powell-Tuck, J3
Brown, RL4
Lennard-Jones, JE5
-
4
-
-
0018888679
-
Treatment of Crohn's disease with 6-mercaptopurine: a long-term, randomized, double-blind study
-
DH Present BI Korelitz N Wisch JL Glass DB Sachar BS Pasternack Treatment of Crohn's disease with 6-mercaptopurine: a long-term, randomized, double-blind study N Engl J Med 302 1980 981 987
-
(1980)
N Engl J Med
, vol.302
, pp. 981-987
-
-
Present, DH1
Korelitz, BI2
Wisch, N3
Glass, JL4
Sachar, DB5
Pasternack, BS6
-
6
-
-
0028790186
-
A controlled double blind study of azathioprine in the management of Crohn's disease
-
S Candy J Wright M Gerber G Adams M Gerig R Goodman A controlled double blind study of azathioprine in the management of Crohn's disease Gut 37 1995 674 678
-
(1995)
Gut
, vol.37
, pp. 674-678
-
-
Candy, S1
Wright, J2
Gerber, M3
Adams, G4
Gerig, M5
Goodman, R6
-
7
-
-
0000951627
-
6-Mercaptopurine (6MP) + prednisone therapy for newly diagnosed pediatric Crohn's disease (CD): a prospective, multicenter, placebo-controlled clinical trial (abstr)
-
J Markowitz K Grancher F Mandel F Daum the 6MP Collaborative Group 6-Mercaptopurine (6MP) + prednisone therapy for newly diagnosed pediatric Crohn's disease (CD): a prospective, multicenter, placebo-controlled clinical trial (abstr) Gastroenterology 114 1998 A1032
-
(1998)
Gastroenterology
, vol.114
, pp. A1032
-
-
Markowitz, J1
Grancher, K2
Mandel, F3
Daum, F4
the 6MP Collaborative Group5
-
8
-
-
0029134702
-
Azathioprine and 6-mercaptopurine in Crohn's disease: a meta-analysis
-
DC Pearson GR May GH Fick LR Sutherland Azathioprine and 6-mercaptopurine in Crohn's disease: a meta-analysis Ann Intern Med 122 1995 132 142
-
(1995)
Ann Intern Med
, vol.122
, pp. 132-142
-
-
Pearson, DC1
May, GR2
Fick, GH3
Sutherland, LR4
-
10
-
-
0025034447
-
Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thioguanine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients
-
GLC Chan GR Erfmann SA Gruber AJ Matas DM Canafax Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thioguanine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients J Clin Pharmacol 30 1990 358 363
-
(1990)
J Clin Pharmacol
, vol.30
, pp. 358-363
-
-
Chan, GLC1
Erfmann, GR2
Gruber, SA3
Matas, AJ4
Canafax, DM5
-
11
-
-
0024818659
-
Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia
-
L Lennard JS Lilleyman Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia J Clin Oncol 7 1989 1816 1823
-
(1989)
J Clin Oncol
, vol.7
, pp. 1816-1823
-
-
Lennard, L1
Lilleyman, JS2
-
12
-
-
0028054901
-
Kinetics of mercaptopurine and thioguanine nucleotides in renal transplant recipients during azathioprine treatment
-
S Bergan HE Rugstad O Bentdal L Endresen O Stokke Kinetics of mercaptopurine and thioguanine nucleotides in renal transplant recipients during azathioprine treatment Ther Drug Monit 16 1994 13 20
-
(1994)
Ther Drug Monit
, vol.16
, pp. 13-20
-
-
Bergan, S1
Rugstad, HE2
Bentdal, O3
Endresen, L4
Stokke, O5
-
13
-
-
0028881322
-
An intravenous loading dose of azathioprine decreases the time to response in patients with Crohn's disease
-
WJ Sandborn EC Van Os BJ Zins WJ Tremaine DC Mays JJ Lipsky An intravenous loading dose of azathioprine decreases the time to response in patients with Crohn's disease Gastroenterology 109 1995 1808 1817
-
(1995)
Gastroenterology
, vol.109
, pp. 1808-1817
-
-
Sandborn, WJ1
Van Os, EC2
Zins, BJ3
Tremaine, WJ4
Mays, DC5
Lipsky, JJ6
-
14
-
-
0018292707
-
Rederived values of the eight co-efficients of the Crohn's disease activity index (CDAI)
-
WR Best JN Becktel JW Singleton Rederived values of the eight co-efficients of the Crohn's disease activity index (CDAI) Gastroenterology 77 1979 843 846
-
(1979)
Gastroenterology
, vol.77
, pp. 843-846
-
-
Best, WR1
Becktel, JN2
Singleton, JW3
-
15
-
-
0018822866
-
Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
RN Weinshilboum SL Sladek Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity Am J Hum Genet 32 1980 651 662
-
(1980)
Am J Hum Genet
, vol.32
, pp. 651-662
-
-
Weinshilboum, RN1
Sladek, SL2
-
17
-
-
0028071632
-
Oral budesonide for active Crohn's disease
-
GR Greenberg BG Feagan F Martin LR Sutherland ABR Thomsen CN Williams LG Nilsson T Persson the Canadian Inflammatory Bowel Disease Study Group Oral budesonide for active Crohn's disease N Engl J Med 331 1994 836 841
-
(1994)
N Engl J Med
, vol.331
, pp. 836-841
-
-
Greenberg, GR1
Feagan, BG2
Martin, F3
Sutherland, LR4
Thomsen, ABR5
Williams, CN6
Nilsson, LG7
Persson, T8
the Canadian Inflammatory Bowel Disease Study Group9
-
18
-
-
0032491040
-
A comparison of budesonide and mesalamine for active Crohn's disease
-
OO Thomsen A Cortot D Jewell JP Wright T Winter FT Veloso M Vatn T Persson E Pettersson for the International Budesonide-Mesalamine Study Group A comparison of budesonide and mesalamine for active Crohn's disease N Engl J Med 339 1998 370 374
-
(1998)
N Engl J Med
, vol.339
, pp. 370-374
-
-
Thomsen, OO1
Cortot, A2
Jewell, D3
Wright, JP4
Winter, T5
Veloso, FT6
Vatn, M7
Persson, T8
Pettersson, E9
for the International Budesonide-Mesalamine Study Group10
-
19
-
-
0021835640
-
Phase 1 in a clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion
-
S Zimm LJ Ettinger JS Locenberg BA Kamen TJ Vietti J Belasco N Coglinao-Shutta F Balis LE Lavi JM Collins DG Poplack Phase 1 in a clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion Cancer Res 45 1985 1869 1873
-
(1985)
Cancer Res
, vol.45
, pp. 1869-1873
-
-
Zimm, S1
Ettinger, LJ2
Locenberg, JS3
Kamen, BA4
Vietti, TJ5
Belasco, J6
Coglinao-Shutta, N7
Balis, F8
Lavi, LE9
Collins, JM10
Poplack, DG11
-
20
-
-
0025160749
-
A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors
-
PC Adamson S Zimm AH Ragab SM Steinberg F Balis BA Kamen TJ Vietti A Gillespie DG Poplack A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors Cancer Chemother Pharmacol 26 1990 343 344
-
(1990)
Cancer Chemother Pharmacol
, vol.26
, pp. 343-344
-
-
Adamson, PC1
Zimm, S2
Ragab, AH3
Steinberg, SM4
Balis, F5
Kamen, BA6
Vietti, TJ7
Gillespie, A8
Poplack, DG9
-
21
-
-
0028899859
-
Methotrexate for the treatment of Crohn's disease
-
BG Feagan J Rochon RN Fedorak EJ Irvine G Wild L Sutherland AH Steinhart GR Greenberg R Gillies M Hopkins SB Hanauer JWD McDonald for the North American Crohn's Disease Study Group investigators Methotrexate for the treatment of Crohn's disease N Engl J Med 332 1995 292 297
-
(1995)
N Engl J Med
, vol.332
, pp. 292-297
-
-
Feagan, BG1
Rochon, J2
Fedorak, RN3
Irvine, EJ4
Wild, G5
Sutherland, L6
Steinhart, AH7
Greenberg, GR8
Gillies, R9
Hopkins, M10
Hanauer, SB11
McDonald, JWD12
for the North American Crohn's Disease Study Group investigators13
-
22
-
-
0028047268
-
Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease
-
EJ Irvine B Feagan J Rochon A Archambault RN Fedorak A Groll D Kinnear F Saibil JWD McDonald for the Canadian Crohn's Relapse Prevention Trial Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease Gastroenterology 106 1994 287 296
-
(1994)
Gastroenterology
, vol.106
, pp. 287-296
-
-
Irvine, EJ1
Feagan, B2
Rochon, J3
Archambault, A4
Fedorak, RN5
Groll, A6
Kinnear, D7
Saibil, F8
McDonald, JWD9
for the Canadian Crohn's Relapse Prevention Trial10
-
23
-
-
0025148411
-
A reversed-phase high-performance liquid chromatography approach in determining total red blood cell concentrations of 6-thioguanine, 6-mercaptopurine, methylthioguanine, and methylmercaptopurine in a patient receiving thiopurine therapy
-
GR Erdmann LA France BC Bostrom DM Canafax A reversed-phase high-performance liquid chromatography approach in determining total red blood cell concentrations of 6-thioguanine, 6-mercaptopurine, methylthioguanine, and methylmercaptopurine in a patient receiving thiopurine therapy Biomed Chromatogr 4 1990 47 51
-
(1990)
Biomed Chromatogr
, vol.4
, pp. 47-51
-
-
Erdmann, GR1
France, LA2
Bostrom, BC3
Canafax, DM4
-
24
-
-
0015220432
-
Controlled trial of azathioprine in Crohn's disease
-
J Rhodes D Bainton P Beck H Campbell Controlled trial of azathioprine in Crohn's disease Lancet 2 1971 1273 1276
-
(1971)
Lancet
, vol.2
, pp. 1273-1276
-
-
Rhodes, J1
Bainton, D2
Beck, P3
Campbell, H4
-
27
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease
-
SR Targan SB Hanauer SJH van Deventer L Mayer DH Present TAJ Braakman KL DeWoody TF Schaible P Rutgeerts the Crohn's Disease cA2 Study Group A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease N Engl J Med 337 1997 1029 1035
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, SR1
Hanauer, SB2
van Deventer, SJH3
Mayer, L4
Present, DH5
Braakman, TAJ6
DeWoody, KL7
Schaible, TF8
Rutgeerts, P9
the Crohn's Disease cA2 Study Group10
-
28
-
-
0025331198
-
Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
-
L Lennard JS Lilleyman J Van Loon RN Weinshilboum Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia Lancet 336 1990 225 229
-
(1990)
Lancet
, vol.336
, pp. 225-229
-
-
Lennard, L1
Lilleyman, JS2
Van Loon, J3
Weinshilboum, RN4
-
29
-
-
0032212759
-
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
-
AJ Black HL McLeod HA Capell RH Powrie LK Matowe SC Pritchard ESR Collie-Duguid DM Reid Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine Ann Intern Med 129 1998 716 718
-
(1998)
Ann Intern Med
, vol.129
, pp. 716-718
-
-
Black, AJ1
McLeod, HL2
Capell, HA3
Powrie, RH4
Matowe, LK5
Pritchard, SC6
Collie-Duguid, ESR7
Reid, DM8
-
30
-
-
0029794073
-
6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity
-
C Cuffari Y Theoret S Latour G Seidman 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity Gut 39 1996 401 406
-
(1996)
Gut
, vol.39
, pp. 401-406
-
-
Cuffari, C1
Theoret, Y2
Latour, S3
Seidman, G4
-
31
-
-
0028269944
-
Mercaptopurine metabolism and the risk of relapse in childhood lymphoblastic leukaemia
-
JS Lilleyman L Lennard Mercaptopurine metabolism and the risk of relapse in childhood lymphoblastic leukaemia Lancet 343 1994 1188 1190
-
(1994)
Lancet
, vol.343
, pp. 1188-1190
-
-
Lilleyman, JS1
Lennard, L2
-
32
-
-
0024457688
-
6-mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity
-
DH Present SJ Meltzer MP Krumholz A Wolke BI Korelitz 6-mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity Ann Intern Med 111 1989 641 649
-
(1989)
Ann Intern Med
, vol.111
, pp. 641-649
-
-
Present, DH1
Meltzer, SJ2
Krumholz, MP3
Wolke, A4
Korelitz, BI5
-
33
-
-
0027164795
-
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years experience
-
WR Connell MA Kamm JK Ritchie JE Lennard-Jones Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years experience Gut 34 1993 1081 1085
-
(1993)
Gut
, vol.34
, pp. 1081-1085
-
-
Connell, WR1
Kamm, MA2
Ritchie, JK3
Lennard-Jones, JE4
-
34
-
-
0031680256
-
Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease
-
BS Kirschner Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease Gastroenterology 115 1998 813 821
-
(1998)
Gastroenterology
, vol.115
, pp. 813-821
-
-
Kirschner, BS1
-
35
-
-
0020512528
-
Childhood leukemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia
-
L Lennard CA Rees JS Lilleyman JL Maddocks Childhood leukemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia Br J Clin Pharmacol 16 1983 359 363
-
(1983)
Br J Clin Pharmacol
, vol.16
, pp. 359-363
-
-
Lennard, L1
Rees, CA2
Lilleyman, JS3
Maddocks, JL4
-
36
-
-
0028293868
-
The role of leukopenia in the 6-mercaptopurine-induced remission of refractory Crohn's disease
-
T Colonna BI Korelitz The role of leukopenia in the 6-mercaptopurine-induced remission of refractory Crohn's disease Am J Gastroenterol 89 1994 362 366
-
(1994)
Am J Gastroenterol
, vol.89
, pp. 362-366
-
-
Colonna, T1
Korelitz, BI2
|