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Volumn 13, Issue 9, 1999, Pages 615-619

A rapid selection/amplification procedure for high-level expression of recombinant protein in a metal-amplifiable mammalian expression system

Author keywords

Amplification; Chinese hamster ovary cells; Metallothionein; Recombinant protein expression; Selection

Indexed keywords

CHO CELL; CLONE; EXPRESSION VECTOR; GENE AMPLIFICATION; GENETIC SCREENING; METALLOTHIONEIN; PROTEIN EXPRESSION; RECOMBINANT PROTEIN;

EID: 0032873911     PISSN: 0951208X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008926708028     Document Type: Article
Times cited : (8)

References (10)
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  • 2
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  • 3
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  • 4
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    • High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification
    • Cockett MI, Bebbington CR, Yarranton GT (1990) High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. Bio/Technology 8: 662-667.
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    • High frequency induction by 5-azacytidine of proline independence in CHO K1 cells
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  • 7
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    • Human metallothionein genes: Molecular cloning and sequence analysis of the mRNA
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  • 8
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    • Selection and coamplifiaction of heterologous genes in mammalian cells
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  • 9
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    • Hyperinducible gene expression from a metallothionein promoter containing additional metal-responsive elements
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.