Eye movements reflect impaired face processing in patients with schizophrenia

Biological Psychiatry

Volumn 46, Issue 7, 1999, Pages 963-969

  Manor, Barry R ^a   Gordon, Evian ^a,e   Williams, Leanne M ^b   Rennie, Chris J ^a   Bahramali, Homayoun ^a   Latimer, Cyril R ^c   Barry, Robert J ^d   Meares, Russell A ^a  

^a WESTMEAD HOSPITAL   (Australia)

^b UNIVERSITY OF NEW ENGLAND   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF WOLLONGONG   (Australia)

^e University of Sydney   (Australia)

Author keywords

Eye movements; Eye tracking; Face stimulus; Geometric stimulus; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EYE MOVEMENT; EYE TRACKING; FACE; FACIES; FEMALE; HUMAN; INFORMATION PROCESSING; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA;

ADULT; ATTENTION; EYE MOVEMENTS; FACIAL EXPRESSION; FEMALE; FIXATION, OCULAR; HUMANS; INTERPERSONAL RELATIONS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; REFERENCE VALUES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 0032873697     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00038-4     Document Type: Article

References (44)

1. Abel L.A., Levin S., Holzman P.S. Abnormalities of smooth pursuit and saccadic control in schizophrenia and affective disorders. Vision Res. 32:1992;1009-1014.
2. Diagnostic and Statistical Manual of Mental Disorders(DSM-IIIR). 3rd, Revised edn. 1987;American Psychiatric Press, Washington, DC.
3. Carter C.S., Robertson L.C., Chaderjian M.R., Celaya L.J., Nordahl T.E. Attentional asymmetry in schizophrenia controlled and automatic processes . Biol Psychiatr. 31:1992;909-918.
4. David A.S. Perceptual asymmetry for happy-sad chimeric faces effects of mood . Neuropsychologia. 27:1989;1289-1300.
5. David A.S., Cutting J.C. Affect, affective disorder and schizophrenia. A neuropsychological investigation of right hemisphere function. Brit J Psychiatry. 156:1990;491-495.
6. David A.S. Spatial and selective attention in the cerebral hemispheres in depression, mania, and schizophrenia. Brain Cognit. 23:1993;166-180.
7. Early T.S., Posner M.I., Reiman E.M., Raichle M.E. Hyperactivity of the left striato-pallidal projection. Part I: Lower level theory . Psychiatr Dev. 7:1989;85-108.
8. Frith C.D., Stevens M., Johnstone E.C., Owens D.G., Crow T.J. Integration of schematic faces and other complex objects in schizophrenia. J Nerv Ment Disease. 171:1983;34-39.
9. Gaebel W., Ulrich G., Frick K. Visuomotor performance of schizophrenic patients and normal controls in a picture viewing task. Biol Psychiatry. 22:1987;1227-1237.
10. Gaebel W. Visuomotor behavior in schizophrenia. Pharmacopsychiatry. 22:(suppl 1):1989;29-34.
11. Geschwind N. Specializations of the human brain. Sci Am. 241:1979;180-199.
12. Gordon E., Coyle S., Anderson J., Healey P., Cordaro J., Latimer C., Meares R. Eye movement response to a facial stimulus in schizophrenia. Biol Psychiatry. 31:1992;626-629.
13. Griffith J.H., Frith C.D., Eysenck S.B. Psychoticism and thought disorder in psychiatric patients. Brit J Soc Clin Psychol. 19:1980;65-71.
14. Griffiths A.N., Marshall R.W., Richens A. Saccadic eye movement analysis as a measure of drug effects on human psychomotor performance. Brit J Clin Pharmacol. 18:(suppl 1):1984;73S-82S.
15. Harvey S.A., Nelson E., Haller J.W., Early T.S. Lateralized attentional abnormality in schizophrenia is correlated with severity of symptoms. Biol Psychiatry. 33:1993;93-99.
16. Hemsley D.R. Schizophrenia - A cognitive model and its implications for psychological intervention. Behav Mod. 20:1996;139-169.
17. Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 13:1987;261-276.
18. Knight R.A., Elliott D.S., Freedman E.G. Short-term visual memory in schizophrenics. J Abnorm Psychol. 94:1985;427-442.
19. Kojima T., Matsushima E., Ando K., Ando H., Sakurada M., Ohta K., et al. Exploratory eye movements and neuropsychological tests in schizophrenic patients. Schizophr Bull. 18:1992;85-94.
20. Kurachi M., Matsui M., Kiba K., Suzuki M., Tsunoda M., Yamaguchi N. Limited visual search on the WAIS Picture Completion test in patients with schizophrenia. Schizophr Res. 12:1994;75-80.
21. Liddle P.F. The symptoms of chronic schizophrenia. A re-examination of the positive- negative dichotomy. Brit J Psychiatry. 151:1987;145-151.
22. Lipton R.B., Levy D.L., Holzman P.S., Levin S. Eye movement dysfunctions in psychiatric patients a review . Schizophr Bull. 9:1983;13-32.
23. Loftus G.R., Mackworth N.H. Cognitive determinants of fixation location during picture viewing. J Exp Psychol Hum Percept Perform. 4:1978;565-572.
24. Manor B.R., Gordon E., Touyz S.W. Consistency of the first fixation when viewing a standard geometric stimulus. Int J Psychophysiol. 20:1995;1-9.
25. Maruff P., Hay D., Malone V., Currie J. Asymmetries in the covert orienting of visual spatial attention in schizophrenia. Neuropsychologia. 33:1995;1205-1223.
26. Mazurski E.J., Bond N.W. A new series of slides depicting facial expressions of affect a comparison with the pictures of facial affect series . Aust J Psychol. 45:1993;41-47.
27. Noton D., Stark L. Eye movements and visual perception. Sci Am. 224:1971;35-43.
28. Park S., Holzman P.S. Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry. 49:1992;975-982.
29. Park S., Holzman P.S. Association of working memory deficit and eye tracking dysfunction in schizophrenia. Schizophr Res. 11:1993;55-61.
30. Phillips M.L., Young A.W., Senior C., Brammer M., Andrew C., Calder A.J., et al. A specific neural substrate for perceiving facial expressions of disgust. Nature. 389:1997;495-498.
31. Phillips M.L., David A.S. Visual scan paths are abnormal in deluded schizophrenics. Neuropsychologia. 35:1997;99-105.
32. Phillips M.L., David A.S. Viewing strategies for simple and chimeric faces an investigation of perceptual bias in normals and schizophrenic patients using visual scan paths . Brain Cognit. 35:1997;225-238.
33. Phillips M.L., David A.S. Abnormal visual scan paths a psychophysiological marker of delusions in schizophrenia . Schizophr Res. 29:1998;235-245.
34. Posner M.I., Early T.S., Reiman E.M., Pardo P.J., Dhawan M. Asymmetries in hemispheric control of attention in schizophrenia. Arch Gen Psychiatry. 45:1988;814-821.
35. Puce A., Allison T., Gore J.C., McCarthy G. Face-sensitive regions in human extrastriate cortex studied by functional MRI. J Neurophysiol. 74:1995;1192-1199.
36. Radant A.D., Hommer D.W. A quantitative analysis of saccades and smooth pursuit during visual pursuit tracking. A comparison of schizophrenics with normals and substance abusing controls. Schizophr Res. 6:1992;225-235.
37. Reuter-Lorenz P.A., Kinsbourne M., Moscovitch M. Hemispheric control of spatial attention. Brain Cognit. 12:1990;240-266.
38. Rey A. L'examen psychologique dans les cas d'encephalopathie traumatique (French). Arch Psychol. 28:1942;286-340.
39. Robins L.N., Wing J., Wittchen H.U., Helzer J.E., Babor T.F., Burke J., et al. The Composite International Diagnostic Interview (CIDI). Arch Gen Psychiatry. 45:1988;1069-1077.
40. Schwartz-Place E.J., Gilmore G.C. Perceptual organization in schizophrenia. J Abnorm Psychol. 89:1980;409-418.
41. Sergent J, Ohta S, MacDonald B, Zuck E, et al (1994): Segregated processing of facial identity and emotion in the human brain: a PET study. In: Bruce V, Humphreys GW, editors. Object and Face Recognition, 1(2/3) edn. Hove, England: Lawrence Erlbaum Associates, pp 349-369.
42. Silberman E.K., Weingartner H. Hemispheric lateralization of functions related to emotion. [Review] [155 refs]. Brain Cognit. 5:1986;322-353.
43. Streit M., Wolwer W., Gaebel W. Facial-affect recognition and visual scanning behaviour in the course of schizophrenia. Schizophr Res. 24:1997;311-317.
44. Wells D.S., Leventhal D. Perceptual grouping in schizophrenia replication of Place and Gilmore . J Abnorm Psychol. 93:1984;231-234.