Rhodopeptins (Mer-N1033), novel cyclic tetrapeptides with antifungal activity from Rhodococcus sp. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

Journal of Antibiotics

Volumn 52, Issue 8, 1999, Pages 695-699

  Chiba, Hiroyuki ^a   Agematu, Hitosi ^a   Kaneto, Rei ^a   Terasawa, Tadashi ^a   Sakai, Kazuya ^a   Dobashi, Kazuyuki ^a   Yoshioka, Takeo ^a  

^a MERCIAN CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIFUNGAL AGENT; RHODOPEPTIN; TETRAPEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG ISOLATION; NONHUMAN; PRIORITY JOURNAL; RHODOCOCCUS;

CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; RHODOCOCCUS;

EID: 0032873447     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.695     Document Type: Article

References (14)

1. CHIBA, H.; H. AGEMATU, K. DOBASHI & T. YOSHIOKA: Rhodopeptins, novel cyclic tetrapeptides with antifungal activity. II. Structure elucidation. J. Antibiotics 52: 700-709, 1999
2. LECHEVALIER, H. A.: Nocardioform Actinomycetes. In BERGEY'S Manual of Systematic Bacteriology. Vol 4. Eds., S. T. WILLIAMS et al., pp. 2348-2408, Williams & Wilkins Co., 1989
3. HASEGAWA, T.; M. TAKIZAWA & S. TANIDA: A rapid analysis for chemical grouping of aerobic actinomycetes. J. Gen. Appl. Microbiol. 29: 319-322, 1983
4. YANO, I. & I. TOMIYASU: In Manual for Identification of Actinomycetes, Ed., A. SEINO, pp. 104-130, The Society for Actinomycetes Japan, Tokyo, 1985
5. FUKAZAWA, Y.; T. NISHIKAWA, K. UCHIDA, T. SHINODA, K. NISHIMURA & T. HAMAMOTO: A proposal for the standardization in the field of medical mycology. Jpn. J. Med. Mycol. 32: 239-260, 1991
6. MOSMANN, T: Rapid colorimetric assay for cellular growth and survival. Application to proliferation and cytotoxicity assay. J. Immunol. Methods 65: 55-63, 1983
7. BENZ, F.; F. KNÜSEL, J. NÜESCH, H. TREICHLER, W. VOSER, R. NYFELER & W. KELLER-SCHIERLEIN: Echinocandin B, a new polypeptide antibiotic from Aspergillus nidurans var. echinulatus. Helv. Chim. Acta 57: 2459-2477, 1974
8. TAKESAKO, K.; K. IKAI, F. HARUNA, M. ENDO, K. SHIMANAKA, E. SONO, T. NAKAMURA, I. KATO & H. YAMAGUCHI: Aureobasidins, new antifungal antibiotics. Taxonomy, fermentation, isolation, and properties. J. Antibiotics 44: 919-924, 1991
9. BESSON, F.; F. PEYPOUX, G. MICHEL & L. DELCAMBE: Characterization of iturin A in antibiotics from various strains of Bacillus subtilis. J. Antibiotics 29: 1043-1049, 1976
10. CLOSSE, A. & R. HUGUENIN: Isolation and structure elucidation of chlamydocin. Helv. Chim. Acta 57: 533-545, 1974
11. HIROTA, A.; A. SUZUKI, K. AIZAWA & S. TAMURA: Structure of Cyl-2, a novel cyclotetrapeptide from Cylindrocladium scoparium. Agric. Biol. Chem. 37: 955-956, 1973
12. LEISCH, J. M.; C. C. SWEELEY, G. D. STAFFELD, M. S. ANDERSON, D. J. WEBER & R. P. SCHEFFER: Structure of HC-toxin, a cyclic tetrapeptide from Helminthosporium carbonum. Tetrahedron 38: 45-48, 1982
13. ITAZAKI, H.; K. NAGASHIMA, K. SUGITA, H. YOSHIDA, Y. KAWAMURA, Y. YASUDA, K. MaTSUMOTO, K. ISHII, N. UOTANI, H. NAKAI, A. TERUI, S. YOSHIMATSU, Y. IKENISHI & Y. NAKAGAWA: Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents. J. Antibiotics 43: 1524-1532, 1990
14. UMEHARA, K.; K. NAKAHARA, S. KIYOTO, M. IWAMI, M. OKAMOTO, H. TANAKA, M. KOHSAKA, H. AOKI & H. IMANAKA: Studies on WF-3161, a new antitumor antibiotic. J. Antibiotics 36: 478-482, 1983