메뉴 건너뛰기




Volumn 146, Issue 1, 1999, Pages 10-18

The acetylcholinesterase inhibitor, ENA 713 (Exelon), attenuates the working memory impairment induced by scopolamine in an operant DNMTP task in rats

Author keywords

Delayed non matching to position task; ENA 713; Exelon; Rat; Scopolamine; Working memory

Indexed keywords

CHOLINESTERASE INHIBITOR; RIVASTIGMINE; SCOPOLAMINE;

EID: 0032872075     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130051082     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 0025824372 scopus 로고
    • Both fornix and anterior thalamic, but not mammillary, lesions disrupt delayed non-matching-to-position memory in rats
    • Aggleton JP, Keith AB, Sahgal A (1991) Both fornix and anterior thalamic, but not mammillary, lesions disrupt delayed non-matching-to-position memory in rats. Behav Brain Res 44: 151-161
    • (1991) Behav Brain Res , vol.44 , pp. 151-161
    • Aggleton, J.P.1    Keith, A.B.2    Sahgal, A.3
  • 2
    • 0029766994 scopus 로고    scopus 로고
    • Efficacy and safety results of the early phase studies with Exelon (ENA 713) in Alzheimer's disease: An overview
    • Anand R, Gharabawi G, Enz A (1996) Efficacy and safety results of the early phase studies with Exelon (ENA 713) in Alzheimer's disease: an overview. J Drug Dev Clin Pract 8:109-116
    • (1996) J Drug Dev Clin Pract , vol.8 , pp. 109-116
    • Anand, R.1    Gharabawi, G.2    Enz, A.3
  • 3
    • 0027969107 scopus 로고
    • Effects of disrupting the cholinergic system on short-term spatial memory in rats
    • Andrews JS, Jansen JHM, Linders S, Princen A (1994) Effects of disrupting the cholinergic system on short-term spatial memory in rats. Psychopharmacology 115:485-494
    • (1994) Psychopharmacology , vol.115 , pp. 485-494
    • Andrews, J.S.1    Jansen, J.H.M.2    Linders, S.3    Princen, A.4
  • 4
    • 0029835472 scopus 로고    scopus 로고
    • Effect of a thyrotrophin-releasing hormone analogue, RX77368, on ampa-induced septal-hippocampal lesioned rats in an operant delayed non-matching to position test
    • Ballard TM, Hunter AJ, Bennett GW (1996) Effect of a thyrotrophin-releasing hormone analogue, RX77368, on AMPA-induced septal-hippocampal lesioned rats in an operant delayed non-matching to position test. Psychopharmacology 127:265-275
    • (1996) Psychopharmacology , vol.127 , pp. 265-275
    • Ballard, T.M.1    Hunter, A.J.2    Bennett, G.W.3
  • 6
    • 0030608714 scopus 로고    scopus 로고
    • A behavioural analysis of the delayed non-matching to position task: The effects of scopolamine, lesions of the fornix and of the prelimbic region on mediating behaviours by rats
    • Chudasama Y, Muir JL (1997) A behavioural analysis of the delayed non-matching to position task: the effects of scopolamine, lesions of the fornix and of the prelimbic region on mediating behaviours by rats. Psychopharmacology 134:73-82
    • (1997) Psychopharmacology , vol.134 , pp. 73-82
    • Chudasama, Y.1    Muir, J.L.2
  • 7
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom J, Anand R, Veach J (1998) A randomized trial evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol 1:55-65
    • (1998) Int J Geriatr Psychopharmacol , vol.1 , pp. 55-65
    • Corey-Bloom, J.1    Anand, R.2    Veach, J.3
  • 8
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurones in Alzheimer's disease
    • Davies P, Maloney AJF (1976) Selective loss of central cholinergic neurones in Alzheimer's disease. Lancet ii:1403
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.F.2
  • 9
    • 0026005792 scopus 로고
    • The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents
    • Dawson GR, Bentley G, Draper F, Rycroft W, Iversen SD, Pagella PG (1991) The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents. Pharmacol Biochem Behav 39:865-871
    • (1991) Pharmacol Biochem Behav , vol.39 , pp. 865-871
    • Dawson, G.R.1    Bentley, G.2    Draper, F.3    Rycroft, W.4    Iversen, S.D.5    Pagella, P.G.6
  • 10
    • 0017652462 scopus 로고
    • Memory and cognitive function in man: Does the cholinergic system have a specific role?
    • Drachmann DA (1977) Memory and cognitive function in man: does the cholinergic system have a specific role? Neurology 27:783-790
    • (1977) Neurology , vol.27 , pp. 783-790
    • Drachmann, D.A.1
  • 11
    • 0026510182 scopus 로고
    • Behavioral microanalysis of spatial delayed alternation performance: Rehearsal through overt behavior, and effects of scopolamine and chlordiazepoxide
    • Dudchenko P, Sarter M (1992) Behavioral microanalysis of spatial delayed alternation performance: rehearsal through overt behavior, and effects of scopolamine and chlordiazepoxide. Psychopharmacology 107:263-270
    • (1992) Psychopharmacology , vol.107 , pp. 263-270
    • Dudchenko, P.1    Sarter, M.2
  • 12
    • 0022384940 scopus 로고
    • Comparative effects of cholinergic drugs and lesions of nucleus basalis or fimbria-fornix on delayed matching in rats
    • Dunnett SB (1985) Comparative effects of cholinergic drugs and lesions of nucleus basalis or fimbria-fornix on delayed matching in rats. Psychopharmacology 87:357-363
    • (1985) Psychopharmacology , vol.87 , pp. 357-363
    • Dunnett, S.B.1
  • 13
    • 0023697229 scopus 로고
    • Cholinergic grafts in the neocortex or hippocampus of aged rats: Reduction of delay-dependent deficits in the delayed non-matching to position task
    • Dunnett SB, Badman F, Rogers DC, Evenden JL, Iversen SD (1988) Cholinergic grafts in the neocortex or hippocampus of aged rats: reduction of delay-dependent deficits in the delayed non-matching to position task. Exp Neurol 102:57-64
    • (1988) Exp Neurol , vol.102 , pp. 57-64
    • Dunnett, S.B.1    Badman, F.2    Rogers, D.C.3    Evenden, J.L.4    Iversen, S.D.5
  • 15
    • 0027429837 scopus 로고
    • Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
    • Enz A, Amstutz R, Boddeke H, Gmelin G, Malanowski J (1993) Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease. Prog Brain Res 98:431-438
    • (1993) Prog Brain Res , vol.98 , pp. 431-438
    • Enz, A.1    Amstutz, R.2    Boddeke, H.3    Gmelin, G.4    Malanowski, J.5
  • 16
    • 0029129910 scopus 로고
    • Clinical classification of dementias
    • Gottfries CG (1995) Clinical classification of dementias. Arch Gerontol Geriatr 21:1-11
    • (1995) Arch Gerontol Geriatr , vol.21 , pp. 1-11
    • Gottfries, C.G.1
  • 17
    • 0029985614 scopus 로고    scopus 로고
    • Effects of infusion of cholinergic drugs into the prefrontal cortex area on delayed matching to position performance in the rat
    • Herremans AHJ, Hijzen TH, Welborn PFE, Olivier B, Slangen JL (1996) Effects of infusion of cholinergic drugs into the prefrontal cortex area on delayed matching to position performance in the rat. Brain Res 711:102-111
    • (1996) Brain Res , vol.711 , pp. 102-111
    • Herremans, A.H.J.1    Hijzen, T.H.2    Welborn, P.F.E.3    Olivier, B.4    Slangen, J.L.5
  • 18
    • 0029129912 scopus 로고
    • Disturbed visuo-spatial orientation in the early stage of Alzheimer's dementia
    • Kalman K, Magloczky E, Janka Z (1995) Disturbed visuo-spatial orientation in the early stage of Alzheimer's dementia. Arch Gerontol Geriatr 21:27-34
    • (1995) Arch Gerontol Geriatr , vol.21 , pp. 27-34
    • Kalman, K.1    Magloczky, E.2    Janka, Z.3
  • 19
    • 0028903561 scopus 로고
    • Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task
    • Kirkby DL, Jones DNC, Higgins GA (1995) Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task. Behav Brain Res 67:221-227
    • (1995) Behav Brain Res , vol.67 , pp. 221-227
    • Kirkby, D.L.1    Jones, D.N.C.2    Higgins, G.A.3
  • 21
    • 0029023752 scopus 로고
    • The effects of AMPA-induced lesions of the medial septum and vertical limb nucleus of the diagonal band of Broca on spatial delayed non-matching to sample and spatial learning in the water maze
    • McAlonan GM, Dawson GR, Wilkinson LO, Robbins TW, Everitt BJ (1995) The effects of AMPA-induced lesions of the medial septum and vertical limb nucleus of the diagonal band of Broca on spatial delayed non-matching to sample and spatial learning in the water maze. Eur J Neurosci 7:1034-1049
    • (1995) Eur J Neurosci , vol.7 , pp. 1034-1049
    • McAlonan, G.M.1    Dawson, G.R.2    Wilkinson, L.O.3    Robbins, T.W.4    Everitt, B.J.5
  • 22
    • 0025821246 scopus 로고
    • Reversal by tetrahydro-aminoacridine of scopolamine-induced memory and performance deficits in rats
    • Murray TK, Cross AJ, Green AR (1991) Reversal by tetrahydro-aminoacridine of scopolamine-induced memory and performance deficits in rats. Psychopharmacology 105:134-136
    • (1991) Psychopharmacology , vol.105 , pp. 134-136
    • Murray, T.K.1    Cross, A.J.2    Green, A.R.3
  • 24
    • 0031081195 scopus 로고    scopus 로고
    • SDZ ENA 713 facilitates central cholinergic function and ameliorates spatial memory impairment in rats
    • Ohara T, Tanaka K, Fukaya H, Demura N, Iimura A, Seno N (1997a) SDZ ENA 713 facilitates central cholinergic function and ameliorates spatial memory impairment in rats. Behav Brain Res 83:229-233
    • (1997) Behav Brain Res , vol.83 , pp. 229-233
    • Ohara, T.1    Tanaka, K.2    Fukaya, H.3    Demura, N.4    Iimura, A.5    Seno, N.6
  • 25
    • 0030941397 scopus 로고    scopus 로고
    • Ameliorating effects of SDZ ENA 713 on age-associated decreases in learning performance and brain choline acetyltransferase activity in rats
    • Ohara T, Fukaya H, Tanaka K, Seno N (1997b) Ameliorating effects of SDZ ENA 713 on age-associated decreases in learning performance and brain choline acetyltransferase activity in rats. Brain Res Bull 43:39-42
    • (1997) Brain Res Bull , vol.43 , pp. 39-42
    • Ohara, T.1    Fukaya, H.2    Tanaka, K.3    Seno, N.4
  • 26
    • 0017360731 scopus 로고
    • Necropsy evidence of central cholinergic deficits in senile dementia
    • Perry EK, Perry RH, Blessed G, Tomlinson BE (1977) Necropsy evidence of central cholinergic deficits in senile dementia. Lancet i:189
    • (1977) Lancet , vol.1 , pp. 189
    • Perry, E.K.1    Perry, R.H.2    Blessed, G.3    Tomlinson, B.E.4
  • 27
    • 0018078940 scopus 로고
    • Correlation of cholinergic abnormalities with senile placques and mental test scores in senile dementia
    • Perry EK, Tomlinson BE, Blessed G, Bergmann K, Gibson PH, Perry RH (1978) Correlation of cholinergic abnormalities with senile placques and mental test scores in senile dementia. BMJ 2:1457-1459
    • (1978) BMJ , vol.2 , pp. 1457-1459
    • Perry, E.K.1    Tomlinson, B.E.2    Blessed, G.3    Bergmann, K.4    Gibson, P.H.5    Perry, R.H.6
  • 28
    • 0030666425 scopus 로고    scopus 로고
    • Effects of scopolamine on delayed-matching-to-sample and paired associates tests of visual memory and learning in human subjects: Comparison with diazepam and implications for dementia
    • Robbins TW, Semple J, Kumar R, Truman MI, Shorter J, Ferraro A, Fox B, McKay G, Matthews K (1997) Effects of scopolamine on delayed-matching-to-sample and paired associates tests of visual memory and learning in human subjects: comparison with diazepam and implications for dementia. Psychopharmacology 134:95-106
    • (1997) Psychopharmacology , vol.134 , pp. 95-106
    • Robbins, T.W.1    Semple, J.2    Kumar, R.3    Truman, M.I.4    Shorter, J.5    Ferraro, A.6    Fox, B.7    McKay, G.8    Matthews, K.9
  • 30
    • 0023904094 scopus 로고
    • A comparative study of visuospatial memory and learning in Alzheimer-type dementia and Parkinson's disease
    • Sahakian BJ, Morris RG, Evenden JL, Heald A, Levy R, Philpot M, Robbins TW (1988) A comparative study of visuospatial memory and learning in Alzheimer-type dementia and Parkinson's disease. Brain 111:695-718
    • (1988) Brain , vol.111 , pp. 695-718
    • Sahakian, B.J.1    Morris, R.G.2    Evenden, J.L.3    Heald, A.4    Levy, R.5    Philpot, M.6    Robbins, T.W.7
  • 32
    • 0029947917 scopus 로고    scopus 로고
    • Effects of the selective angiotensin II receptor antagonists losartan and PD123177 in animal models of anxiety and memory
    • Shepherd J, Bill DJ, Dourish CT, Grewal SS, McLenachan A, Stanhope KJ (1996) Effects of the selective angiotensin II receptor antagonists losartan and PD123177 in animal models of anxiety and memory. Psychopharmacology 126:206-218
    • (1996) Psychopharmacology , vol.126 , pp. 206-218
    • Shepherd, J.1    Bill, D.J.2    Dourish, C.T.3    Grewal, S.S.4    McLenachan, A.5    Stanhope, K.J.6
  • 33
    • 0028810472 scopus 로고
    • Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: Effects of scopolamine, 8-OH-DPAT and EAA antagonists
    • Stanhope KJ, McLenachan AP, Dourish CT (1995) Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists. Psychopharmacology 122:268-280
    • (1995) Psychopharmacology , vol.122 , pp. 268-280
    • Stanhope, K.J.1    McLenachan, A.P.2    Dourish, C.T.3
  • 34
    • 0028007356 scopus 로고
    • Chronic administration of acetylcholinesterase inhibitor in the senescent rat brain
    • Tanaka K, Ogawa N, Asanuma M, Kondo Y, Mori A (1994) Chronic administration of acetylcholinesterase inhibitor in the senescent rat brain. Neurobiol Aging 15:721-725
    • (1994) Neurobiol Aging , vol.15 , pp. 721-725
    • Tanaka, K.1    Ogawa, N.2    Asanuma, M.3    Kondo, Y.4    Mori, A.5
  • 35
    • 0030446532 scopus 로고    scopus 로고
    • Cholinomimetic treatment of Alzheimer's disease
    • Thal LJ (1996) Cholinomimetic treatment of Alzheimer's disease. Prog Brain Res 109:299-309
    • (1996) Prog Brain Res , vol.109 , pp. 299-309
    • Thal, L.J.1
  • 36
    • 0028709150 scopus 로고
    • Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors
    • Weinstock M, Razin M, Chorev M, Enz A (1994) Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors. J Neural Transm (Suppl) 43:219-225
    • (1994) J Neural Transm (Suppl) , vol.43 , pp. 219-225
    • Weinstock, M.1    Razin, M.2    Chorev, M.3    Enz, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.