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Volumn 5, Issue 9, 1999, Pages 985-986

HIV-1 Nef protein: An invitation to a kill

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; VIRUS PROTEIN;

EID: 0032871336     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/12417     Document Type: Short Survey
Times cited : (7)

References (13)
  • 1
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    • Cullen, B.R. HIV-1 auxiliary proteins: Making connections in a dying cell. Cell 93, 685-692 (1998).
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    • Cullen, B.R.1
  • 2
    • 0025743306 scopus 로고
    • Importance of the nef gene for maintenance of high virus loads and for development of AIDS
    • Kestler, H.W. III et al. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65, 651-662 (1991).
    • (1991) Cell , vol.65 , pp. 651-662
    • Kestler H.W. III1
  • 3
    • 0032845027 scopus 로고    scopus 로고
    • HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages
    • Swingler, S. et al. HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nature Med. 5, 997-1003 (1999).
    • (1999) Nature Med. , vol.5 , pp. 997-1003
    • Swingler, S.1
  • 4
    • 0033578072 scopus 로고    scopus 로고
    • Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- And Vpu-inhibitable manner
    • Lama, J. et al. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9, 622-631 (1999).
    • (1999) Curr. Biol. , vol.9 , pp. 622-631
    • Lama, J.1
  • 5
    • 0033578016 scopus 로고    scopus 로고
    • Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
    • Ross, T.M. et al. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Curr. Biol. 9, 613-621 (1999).
    • (1999) Curr. Biol. , vol.9 , pp. 613-621
    • Ross, T.M.1
  • 6
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins, K. L. et al. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391, 397-401 (1998).
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1
  • 7
    • 0029089406 scopus 로고
    • Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys
    • Du, Z. et al. Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell 82, 665-674 (1995).
    • (1995) Cell , vol.82 , pp. 665-674
    • Du, Z.1
  • 8
    • 0030788298 scopus 로고    scopus 로고
    • A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation
    • Alexander, L. et al. A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation. J. Virol. 71, 6094-6099 (1997).
    • (1997) J. Virol. , vol.71 , pp. 6094-6099
    • Alexander, L.1
  • 9
    • 0028485232 scopus 로고
    • HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
    • Baur, A.S. et al. HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1, 373-384 (1994).
    • (1994) Immunity , vol.1 , pp. 373-384
    • Baur, A.S.1
  • 10
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    • Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
    • Skowronski, J. et al. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J. 12, 703-713 (1993).
    • (1993) EMBO J. , vol.12 , pp. 703-713
    • Skowronski, J.1
  • 11
    • 0028878783 scopus 로고
    • Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • Saksela, K. et al. Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J. 14, 484-491 (1995).
    • (1995) EMBO J. , vol.14 , pp. 484-491
    • Saksela, K.1
  • 12
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    • Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
    • Fackler, O.T. et al. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3, 729-739 (1999).
    • (1999) Mol. Cell , vol.3 , pp. 729-739
    • Fackler, O.T.1
  • 13
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    • Genotypic and phenotypic characterization of HIV-1 in patients with primary infection
    • Zhu, T. et al. Genotypic and phenotypic characterization of HIV-1 in patients with primary infection. Science 261, 1179-1181 (1993).
    • (1993) Science , vol.261 , pp. 1179-1181
    • Zhu, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.