Adult granulosa cell tumor of the ovary with foci of hepatic cell differentiation: A report of four cases and comparison with two cases of granulosa cell tumor with Leydig cells

American Journal of Surgical Pathology

Volumn 23, Issue 9, 1999, Pages 1089-1093

  Ahmed, Essam ^a   Young, Robert H ^b   Scully, Robert E ^b  

^a Memorial Health Care ^*  (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Granulosa cell tumor; Hepatocytes; Immunohistochemistry; Leydig cells; Ovary

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CELL DIFFERENTIATION; CELL TYPE; FEMALE; GRANULOSA CELL TUMOR; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; LIVER CELL; OVARY TUMOR;

ADULT; CELL DIFFERENTIATION; FEMALE; GRANULOSA CELL TUMOR; HUMANS; LEYDIG CELLS; LIVER; MALE; MIDDLE AGED; OVARIAN NEOPLASMS;

EID: 0032871257     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199909000-00012     Document Type: Article

References (18)

1. Chadha S, Hoonnebier WJ, Schaberg A. Raised serum alpha feto-protein in Sertoli-Leydig cell tumor (androblastoma) of ovary: report of two cases. Int J Gynecol Pathol 1987;6:82-8.
2. Chumas JC, Rosenwaks Z, Mann WJ, Finkel G, Pastore J. Sertoli-Leydig cell tumor of the ovary producing alpha-fetoprotein. Int J Gynecol Pathol 1984;3:213-9.
3. Donaldson ES, van Nagell JR Jr, Pursell S, Gay EC, Meeker WR, Kashmiri R, van deVoorde J. Multiple biochemical markers in patients with gynecologic malignancies. Cancer 1980;45:948-53.
4. Gagnon S, Tetu B, Silva EG, McCaughey WTE. Frequency of alpha-fetoprotein production by Sertoli-Leydig cell tumors of the ovary: an immunohistochemical study of eight cases. Mod Pathol 1989;2:63-7.
5. Garneau R, Cabanne F. Dysembryome ovarien de type enteroide et bilio-hepatoide avec hyperplasie fonctionelle de cellules sympathicotropes de Berger. A propos d'une observation. Ann Anat Pathol (Paris) 1968;13:423-31.
6. Iezzoni JC, Mills SE, Pelkey TJ, Stoler MH. Inhibin is not an immunohistochemical marker for hepatocellular carcinoma. An example of the potential pitfall in diagnostic immunohistochemistry caused by endogenous biotin. Am J Clin Pathol 1999;111:229-234.
7. Masson P, Theriault JP. Une forme inhabituelle de tumeur ovarienne: epitheliome biliohepatoide. Ann Anat Pathol (Paris) 1956; 1:7-18.
8. Mori H, Onji M, Yoshida A, Fukunishi R. Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Virchows Arch Pathol Anat 1980;387:107-16.
9. Nakashima N, Fukatsu T, Nagasaka T, Sobue M, Takeuchi J. The frequency and histology of hepatic tissue in germ cell tumors. Am J Surg Pathol 1987;11:682-92.
10. Nistal M, Redondo E, Paniagua R. Juvenile granulosa cell tumor of the testis. Arch Pathol Lab Med 1988;122:1129-32.
11. Nogales FF, Concha A, Plata C, Ruiz-Avila I. Granulosa cell tumor of the ovary with diffuse true hepatic differentiation simulating stromal luteinization. Am J Surg Pathol 1993;17:85-90.
12. Prat J, Bhan AK, Dickersin GR, Robboy SJ, Scully RE. Hepatoid yolk sac tumor of the ovary (endodermal sinus tumor with hepatoid differentiation): a light microscopic, ultrastructural and immunohistochemical study of seven cases. Cancer 1982;50:2355-68.
13. Price A, Russell P, Elliot P, Bannatyne P. Composite mucinous and granulosa cell tumor of ovary: case report of a unique neoplasm. Int J Gynecol Pathol 1990;9:372-8.
14. Talerman A. Ovarian Sertoli-Leydig cell tumor (androblastoma) with retiform pattern. A clinicopathologic study. Cancer 1987;60: 3056-64.
15. Ulbright TM, Roth LM, Brodhecker CA. Yolk sac differentiation in germ cell tumors. A morphologic study of 50 cases with emphasis on hepatic, enteric, and parietal yolk sac features. Am J Surg Pathol 1986;10:151-64.
16. Young RH, Kleinman GM, Scully RE. Glioma of the uterus. Report of a case with comments on histogenesis. Am J Surg Pathol 1981;5:695-9.
17. Young RH, Perez-Atayde AR, Scully RE. Ovarian Sertoli-Leydig cell tumor with retiform and heterologous elements. Am J Surg Pathol 1984;8:709-18.
18. Young RH, Prat J, Scully, RE. Ovarian Sertoli-Leydig cell tumors with heterologous elements. (1) Gastrointestinal epithelium and carcinoid: a clinicopathologic analysis of thirty-six cases. Cancer 1982;50:2448-56.