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Volumn 29, Issue 21, 1999, Pages 3811-3820

A practical preparation of thiol carboxylic esters of 2-(isoxazolyl) acetic acids

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ESTER; THIOL DERIVATIVE;

EID: 0032871203     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919908086021     Document Type: Article
Times cited : (5)

References (23)
  • 8
    • 0000813083 scopus 로고
    • eds Trost, B.M. and Fleming, I., Pergamon Press, Oxford, ch.2.5
    • Voss, J. "Comprehensive Organic Synthesis," eds Trost, B.M. and Fleming, I., Pergamon Press, Oxford, 1991, vol. 6, ch.2.5, p. 435-459.
    • (1991) Comprehensive Organic Synthesis , vol.6 , pp. 435-459
    • Voss, J.1
  • 16
    • 85038148001 scopus 로고    scopus 로고
    • note
    • Preparation of the isobutyl ester 1 is the most efficient route to 2 since isobutyl vinylacetate is available for cycloaddition to form the substituted isoxazoline ring. The corresponding carboxylic acid, vinyl acetic acid, is far more expensive and the cycloaddition does not proceed well. Otherwise, we could have produced racemic 2 directly and used any of a number of means to form the thiolester for resolution to (R)-2.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.