The synthesis and antibacterial activity of totarol derivatives. Part 1: Modifications of ring-C and pro-drugs

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 9, 1999, Pages 1953-1964

  Evans, Gary B ^a   Furneaux, Richard H ^a   Gravestock, Michael B ^b   Lynch, Gregory P ^a   Scott, G Kenneth ^c  

^a CALLAGHAN INNOVATION   (New Zealand)

^b ASTRAZENECA   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Antibacterials; Glycosides; Natural products; Terpenes and terpenoids

Indexed keywords

13 (ALPHA MANNOPYRANOSYLOXY)TOTARA 8,11,13 TRIENE; ALPHA MANNOPYRANOSIDE DERIVATIVE; ANTIINFECTIVE AGENT; METICILLIN; PENICILLIN DERIVATIVE; TOTAROL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG MANUFACTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ALKYLATION; ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE; CELL SURVIVAL; DITERPENES; ESTERIFICATION; GLYCOSYLATION; HUMANS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; PRODRUGS; SPECTRUM ANALYSIS;

EID: 0032870418     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00162-5     Document Type: Article

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