M31, a murine homolog of drosophila HP1, is concentrated in the XY body during spermatogenesis

Cytogenetics and Cell Genetics

Volumn 86, Issue 1, 1999, Pages 83-88

  Motzkus, D ^a,c   Singh, P B ^b   Hoyer Fender, Sigrid ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c Niedersachsisches Inst P   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; CHROMOSOME INACTIVATION; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; HETEROCHROMATIN; KARYOTYPE 46,XY; MEIOSIS; MOUSE; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROTEIN DOMAIN; SEX CHROMOSOME; SPERMATOCYTE; SPERMATOGENESIS;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; CELL NUCLEUS; CHROMOSOMAL PROTEINS, NON-HISTONE; DOSAGE COMPENSATION, GENETIC; GENE SILENCING; HETEROCHROMATIN; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MEIOSIS; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MOLECULAR WEIGHT; MUTATION; PROTEIN ISOFORMS; SEX CHROMOSOMES; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0032869824     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Armstrong SJ, Húlten MA, Keohane AM, Turner BM: Different strategies of X-inactivation in germinal and somatic cells: histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline. Expl Cell Res 230:399-402 (1997).
2. Ayoub N, Richler C, Wahrman J: Xist RNA is associated with the transcriptionally inactive XY body in mammalian male meiosis. Chromosoma 106:1-10 (1997).
3. Bunick D, Johnson PA, Johnson TR, Hecht MB: Transcription of the testis-specific mouse protamine 2 gene in a homologous in vitro transcription system. Proc natl Acad Sci, USA 87:891-895 (1990).
4. Burgoyne PS, Mahadevaiah SK, Sutcliffe MJ, Palmer SJ: Fertility in mice requires X-Y pairing and a Y-chromosomal "spermiogenesis" gene mapping to the long arm. Cell 71:391-398 (1992).
5. Calenda A, Allenet B, Escalier D, Bach J-F, Garchon H-J: The meiosis-specific Xmr gene product is homologous to the lymphocyte Xlr protein and is a component of the XY body. EMBO J 13:100-109 (1994).
6. Dreesen TD, Henikoff S, Loughney KA: A pairing-sensitive element that mediates trans-inactivation is associated with the Drosophila brown gene. Genes Dev 5:331-340 (1991).
7. Handel MA, Park C, Kot M: Genetic control of sex-chromosome inactivation during male meiosis. Cytogenet Cell Genet 66:83-88 (1994).
8. Henikoff S, Dreesen TD: Trans-inactivation of the Drosophila brown gene: evidence for transcriptional repression and somatic pairing dependence. Proc natl Acad Sci, USA 86:6704-6708 (1989).
9. Horsley D, Hutchings A, Butcher GW, Singh PB: M32, a murine homologue of Drosophila heterochromatin protein 1 (HP1), localises to euchromatin within interphase nuclei and is largely excluded from constitutive heterochromatin. Cytogenet Cell Genet 73:308-311 (1996.).
10. Jaafar H, Gabriel-Robez O, Rumpler Y: Pattern of ribonucleic acid synthesis in vitro in primary spermatocytes from mouse testis carrying an X-autosome translocation. Chromosoma 98:330-334 (1989).
11. Kierszenbaum AL, Tres LL: Transcription sites in spread meiotic prophase chromosomes from mouse spermatocytes. J Cell Biol 63:923-935 (1974).
12. Kofman-Alfaro S, Chandley AC: Meiosis in the male mouse: an autoradiographic investigation. Chromosoma 31:404-420 (1970).
13. Kralewski M, Novello A, Benavente R: A novel Mr 77,000 protein of the XY body of mammalian spermatocytes: its localisation in normal animals and in Searle's translocation carriers. Chromosoma 106:160-167 (1997).
14. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685 (1970).
15. Latos-Bielenska A, Vogel W: Demonstration of replication patterns in the last premeiotic S-phase of male Chinese hamsters after BrdU pulse labeling. Chromosoma 101:279-283 (1992).
16. Lee JT, Jaenisch R: The (epi)genetic control of mammalian X-chromosome inactivation. Curr Op Genet Dev 7:274-280 (1997).
17. Lenhossek M: Untersuchungen über Spermatogenese. Arch Mikrosk Anat Entwicklungsmech 51:215-318 (1898).
18. Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R: Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 11:156-166 (1997).
19. Matsuda Y, Hirobe T, Chapman VM: Genetic basis of X-Y chromosome dissociation and male sterility in interspecific hybrids. Proc natl Acad Sci, USA 88:4850-4854 (1991).
20. McCarrey JR, Dilworth DD: Expression of Xist in mouse germ cells correlates with X-chromosome inactivation. Nature Genet 2:200-203 (1992).
21. McKee BD, Handel MA: Sex chromosomes, recombination, and chromatin conformation. Chromosoma 102:71-80 (1993).
22. McKee BD, Karpen GH: Drosophila ribosomal RNA genes function as an X-Y pairing site during male meiosis. Cell 61:61-72 (1990).
23. Monesi V: Differential rate of ribonucleic acid synthesis in the autosomes and sex chromosomes during male meiosis in the mouse. Chromosoma 17:11-21 (1965).
24. Nebel BR, Amarose AP, Hackett EM: Calendar of gametogenic development in the prepuberal male mouse. Science 134:832-833 (1961).
25. Oakberg EF: A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal. Am J Anat 99:391-413 (1956).
26. Odartchenko N, Pavillard M: Late DNA replication in male mouse meiotic chromosomes. Science 167:1133-1134 (1970).
27. Odorisio T, Rodriguez TA, Evans EP, Clarke AR, Burgoyne PS: The meiotic checkpoint monitoring synapsis eliminates spermatocytes via p53-independent apoptosis. Nature Genet 18:257-261 (1998).
28. Pardue, ML, Gall JG: Chromosomal localisation of mouse satellite DNA. Science 168:1356-1358 (1970).
29. Paro R, Hogness D: The polycomb protein shares a homologous domain with a heterochromatin associated protein of Drosophila. Proc natl Acad Sci, USA 88:263-267 (1991).
30. Peterson K, Wang G, Horsley D, Richardson JC, Sapienza C, Latham KE, Singh PB: The M31 gene has a complex developmentally regulated expression profile and may encode alternative protein products that possess diverse subcellular localisation patterns. J exp Zool 280:288-303 (1998).
31. Singer-Sam J, Robinson MO, Bellvé AR, Simon MI, Riggs AD: Measurement by quantitative PCR of changes in HPRT, PGK-1, APRT, MTase, and Zfy gene transcripts during mouse spermatogenesis. Nucl Acids Res 18:1255-1259 (1990).
32. Singh PB: Molecular mechanisms of cellular determination: their relation to chromatin structure and parental imprinting. J Cell Sci 107:2653-2668 (1994).
33. Singh PB, Huskisson NS: Chromatin complexes as aperiodic microcrystalline arrays that regulate genome organisation and expression. Dev Genet 22:85-99 (1998).
34. Singh PB, James TC: Chromobox genes and the molecular mechanisms of cellular determination, in Ohlsson R, Hall K, Ritzen M (eds): Genomic Imprinting: Causes and Consequences, pp 71-108 (Cambridge University Press, Cambridge 1995).
35. Singh PB, Miller JR, Pearce JJ, Burton RD, Paro R, James TC, Gaunt SJ: A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucl Acids Res 19:789-793 (1991).
36. Smith A, Benavente R: Meiosis-specific protein selectively associated with sex chromosomes of rat pachytene spermatocytes. Proc natl Acad Sci, USA 98:6938-6942 (1992).
37. Smith A, Benavente R: An Mr 51,000 protein of mammalian spermatogenic cells that is common to the whole XY body and centromeric heterochromatin of autosomes. Chromosoma 103:591-596 (1995).
38. Solari AJ: The behavior of the XY pair in mammals. Int J Cytol 38:273-317 (1974).
39. Tartof KD, Hobbs C, Jones M: A structural basis for variegating position effects. Cell 37:869-878 (1984).
40. Tease C, Cattanach BM: Sex chromosome pairing patterns in male mice of novel Sxr genotypes. Chromosoma 97:390-395 (1989).
41. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc natl Acad Sci, USA 76:4350-4354 (1979).
42. Wettstein D von, Rasmussen SW, Holm PB: The synaptonemal complex in genetic segregation. A Rev Genet 18:331-413 (1984).
43. Wreggett KA, Hill F, James PS, Hutchings A, Butcher GW, Singh PB: A mammalian homolog of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin. Cytogenet Cell Genet 66:99-103 (1994).