Preferential inhibition of CYP1A enzymes in hepatic microsomes by mexiletine

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 24, Issue 2, 1999, Pages 149-153

  Konishi, Hiroki ^a   Morita, K ^a   Minouchi, T ^a   Yamaji, A ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE HOSPITAL   (Japan)

Author keywords

CYP1A; Enzyme inhibition; Mexiletine; Mouse hepatic microsome; Theophylline metabolism

Indexed keywords

BETA NAPHTHOFLAVONE; CYTOCHROME P450; LIVER ENZYME; MEXILETINE; THEOPHYLLINE;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DEMETHYLATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG OXIDATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; LIVER MICROSOME; MALE; MOUSE; NONHUMAN;

EID: 0032868390     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190360     Document Type: Article

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