CD44 is an independent prognostic factor in conventional renal cell carcinomas

Journal of Urology

Volumn 161, Issue 6, 1999, Pages 1984-1987

  Paradis, Valérie ^a   Ferlicot, Sophie ^a   Ghannam, Elie ^a   Zeimoura, Leila ^a   Blanchet, Pascal ^a   Eschwége, Pascal ^a   Jardin, Alain ^a   Benoît, Gérard ^a   Bedossa, Pierre ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

CD44 expression; Conventional renal cell carcinoma; Immunostaining

Indexed keywords

GLYCOPROTEIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CELL INTERACTION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SURVIVAL RATE;

EID: 0032866750     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)68869-6     Document Type: Article

References (22)

1. Störkel, S., Ebbe, J., Adlakha, K., Amin, M., Blute, M. L., Bostwick, D. G., Darson, M., Delahunt, B. and Ickowski, K: Classification of renal cell carcinoma: workgroup No. 1. Cancer, 80: 987, 1997.
2. Medeiros, L. J., Gelb, A. B. and Weiss, L. M.: Renal cell carcinoma. Prognostic significance of morphologic parameters in 121 cases. Cancer, 61: 1639, 1988.
3. Helpap, B.: Grading and prognostic significance of urologic carcinomas. J. Urol., 48: 245, 1992.
4. Fuhrman, S. A., Lasky, L. C. and Limas, C.: Prognostic significance of morphologic parameters in renal cell carcinoma. Am. J. Surg. Pathol., 6: 655, 1982.
5. Flint, A., Grossman, H. B., Liebert, M., Lloyd, R. V. and Bromberg, J.: DNA and PCNA content of renal cell carcinoma and prognosis. Am. J. Clin. Pathol., 103: 14, 1995.
6. Grignon, D. J., Abdel-Malak, M., Mertens, W., Koster, J., Keeney, M., Sakr, W. and Shepherd, R. R.: Prognostic significance of cellular proliferation in renal cell carcinoma: a comparison of synthesis-phase fraction and proliferating cell nuclear antigen index. Mod. Pathol., 8: 18, 1995.
7. Gelb, A. B., Sudilowsky, D., Wu, C. D., Weiss, L. M. and Meideros, L. J.: Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma. Cancer, 80: 1768, 1997.
8. Kaufmann, M., Heider, K. H., Sinn, H. P., von Minckwitz, G., Ponta, H. and Herrlich, P.: CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet, 345:615, 1995.
9. Heider, K. H., Ratschek, M., Zatloukal, K. and Adolf, G. R.: Expression of CD44 isoforms in human renal cell carcinomas. Virchows Arch., 428: 267, 1996.
10. Terpe, H. J., Störkel, S., Zimmer, U., Anquez, V., Fischer, C., Pantel, K. and Günthert, U.: Expression of CD44 isoforms in renal cell tumors: positive correlation to tumor differentiation. Am. J. Pathol., 148: 453, 1996.
11. Fleming, I. D., Cooper, J. S., Henson, D. E., Hutter, R. V. P., Kennedy, B. J., Murphy, G. P., O'Sullivan, B., Sobin, L. H. and Yarbro, J. W.: American Joint Committee on Cancer. Manual for Staging of Cancer. Philadelphia: Lippincott-Raven, 1997.
12. Lannigan, D., Conroy, R., Barry-Walsh, C., Loftus, B., Royston, D. and Leader, M.: A comparative analysis of grading systems in renal adenocarcinoma. Histopathology, 24: 473, 1994.
13. Hofmockel, G., Tsatalpas, P., Muller, H., Dämmrich, J., Foot, M., Maurer-Schultze, B., Müller-Hermelink, H. K. and Frohmüller, H. G. W.: Significance of conventional and new prognostic factors for locally confined renal cell carcinoma. Cancer, 76: 296, 1995.
14. Moch, H., Sauter, G., Buchholz, N., Gasser, T. C., Bubendorf, L., Waldman, F. M. and Mihatsch, M. J.: Epidermal growth factor receptor expression is associated with rapid tumor cell prolferation in renal cell carcinoma. Hum. Pathol., 28: 1255, 1997.
15. Matsumara, Y. and Tarin, D.: Significance of CD44 gene products for cancer diagnosis and disease evaluation. Lancet, 340: 1053, 1992.
16. Screaton, G. R., Bell, M. V., Jackson, D. G., Cornelis, F. B., Gerth, U. and Bell, J. I.: Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci., 89: 12160, 1992.
17. Günthert, U., Hofmann, M., Rudy, W., Reber, S., Zöller, M., Haussmann, I., Matzku, S., Wenzel, A., Ponta, H. and Herrlich, P.: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell, 65: 13, 1991.
18. Stauder, R., Eisterer, W., Thaler, J. and Günthert, U.: CD44 variant isoforms in non-Hodgkin's lymphoma: a new independent prognostic factor. Blood, 85: 2885, 1995.
19. Tanabe, K. K., Ellis, L. M. and Saya, H.: Expression of CD44R1 adhesion molecule in colon carcinomas and metastases. Lancet, 341: 725, 1993.
20. Mayer, B., Jauch, K. W., Günthert, U., Figdor, C. G., Schildberg, F. W., Funke, I. and Johnson, J. P.: De novo expression of CD44 and survival in gastric cancer. Lancet, 342: 1019, 1993.
21. Van Poppel, H., Vandendriessche, H., Boel, K., Mertens, V., Goethuys, H., Haustermans, K., Van Damme, B. and Baert, L.: Microscopic vascular invasion is the most relevant prognosticator after radical nephrectomy for clinically nonmetastatic renal cell carcinoma. J. Urol., 168: 45, 1997.
22. Griffioen, A. W., Coenen, M. J., Damen, C. A., Hellwig, S. M., van Weering, D. H., Vooys, W., Blijham, G. H. and Groenewegen, G.: CD44 is involved in tumor angiogenesis; an activation antigen on human endothelial cells. Blood, 90: 1150, 1997.