Scale-up strategy for bioreactors with Newtonian and non-Newtonian broths

Bioprocess Engineering

Volumn 21, Issue 1, 1999, Pages 21-23

  Diaz, A ^a   Acevedo, F ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

ARTICLE; BIOREACTOR; CELL POPULATION; CONCENTRATION RESPONSE; FERMENTATION; FLOW KINETICS; GEOMETRY; MATHEMATICAL ANALYSIS; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PRIORITY JOURNAL;

EID: 0032866647     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004490050634     Document Type: Article

References (18)

1. 1. Metzner, A.B.; Pigford, R.L.: Scale-up theory and its limitations. In: Fleming, R. (Ed.): Scale-up in Practice, pp. 16-47. New York: Reinhold Publishing Corp. 1958
2. 2. Aiba, S.; Humphrey, A.E.; Millis, N.: Biochemical Engineering, 2nd ed., chap. 7. New York: Academic Press 1973a
3. 3. Wang, D.I-C.; Cooney, C.L.; Demain, A.L.; Dunnill, P.; Humphrey, A.E.; Lilly, M.D.: Fermentation & Enzyme Technology, chap. 10. New York: J. Wiley & Sons 1979
4. 4. Ju, L.K.; Chase, G.G.: Improved scale-up strategies of bioreactors. Bioprocess Eng. 8 (1992) 49-53
5. 5. Aiba, S.; Humphrey, A.E.; Millis, N.: op. cit., pp. 165-167, 1973b
6. 6. Einsele, A.: Scaling of bioreactors, theory and reality. Paper 4.13, V International Fermentation Symposium, Berlin 1976
7. 7. Sumino, Y.; Kanzaki, T.; Fukuda, H.: Oxygen transfer in L-glutamic acid fermentation by oleic acid-requiring organism. J. Ferment. Technol. 46 (1968) 1040-1047
8. 8. Pirt, S.J.: Principles of Microbe and Cell Cultivation, pp. 111-112. Oxford: Blackwell Scientific Publications 1975
9. 9. Wang, D.I-C.; Fewkes, R.C.J.: Effect of operating and geometric parameters on the behavior of non-Newtonian, mycelial, antibiotic fermentations. Dev. Ind. Microbiol. 18 (1977) 39-56
10. 10. Konstantinov, K.B.; Nishio, N.; Seki, T.; Yoshida, T.: Physiologically motivated strategies for control of the fed-batch cultivation of recombinant Escherichia coli for phenylalanine production. J. Ferment. Bioeng. 71 (1991) 3350-3355
11. 11. Leitão, J.H.; Sá-Correia, I.: Oxygen-dependent alginate synthesis and enzymes in Pseudomonas aeruginosa. J. Gen. Microbiol. 139 (1993) 441-445
12. 12. Peña, C.; Galindo, E.: Effect of dissolved oxygen during culture of Azotobacter vinelandii on the production and composition of alginate. Paper P4-16, X International Biotechnology Symposium, Sydney 1996
13. 13. Razo-Flores, E.; Pérez, F.; de la Torre, M.: Scale-up of Bacillus thuringensis fermentation based on oxygen transfer. J. Ferment. Biotechnol. 83 (1997) 561-564
14. 14. Michel, B.J.; Miller, S.A.: Power requirements of gas-liquid agitated systems. AIChE Journal 8 (1962) 262-266
15. 15. Rushton, J.H.; Costick, E.W.; Everett, H.J.: Power characteristics of mixing impellers. Part 2. Chem. Eng. Progr. 46 (1950) 467-476
16. 16. Fukuda, H.; Sumino, Y.; Kanzaki, T.: Scale-up of fermentors. (I) Modified equations for volumetric oxygen transfer coefficient. J. Ferment Technol. 46 (1968) 829-837
17. 17. Taguchi, H.; Imanaka, T.; Teramoto, S.; Takatsu, M.: Scale-up of glucoamylase fermentation by Endomyces sp. J. Ferment. Technol. 46 (1968) 823-828
18. 18. Blanch, H.W.; Clark, D.S.: Biochemical Engineering, pp. 357. New York: M. Dekker 1996